Protein Alignment Cyp4d20 and cyp4b1.2

DIOPT Version :10

• Sequence 1: NP_647723.2
• Gene: Cyp4d20 / 38311
• FlyBaseID: FBgn0035344
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: NP_001017348.1
• Gene: cyp4b1.2 / 550102
• XenbaseID: XB-GENE-963387
• Length: 515
• Species: Xenopus tropicalis
• Alignment Length: 516
• Identity: 178/516 - (34%)
• Similarity: 270/516 - (52%)
• Gaps: 40/516 - (7%)

  Fly     2 WLTLITGALILLLTWDFGRKRQRVLAFEKSAIPGPISIPILGCGLQALHLG--AENIIGWVGEKF 64
            ::.|:...|:||..:.. ..|.|..|......|||.:..:.|...|....|  .:.::.||
 Frog    24 FVALLCVVLLLLKAYAL-YSRGRRFAAALVPFPGPPAHWLYGHVNQFRRDGKDLDRLMVWV---- 83

  Fly    65 DKYGKTFRFWILGE---SLIYTKDLQYFETILS-STTLLEKGQLYEYLRPFLNDGLLVSTGRKWH 125
            :||...|..|| |:   :||.| |..|.:.:.. |......|  |.:|.|::..|||:.:|..|.
 Frog    84 NKYPNAFPLWI-GKFFGTLIIT-DPDYAKVVFGRSDPKTSTG--YNFLVPWIGKGLLILSGNTWF 144

  Fly   126 ARRKIFTHAFHFKVLEHYVEIMDRHSSVMVDNLRKVADGKTAVDMLKYVSLAALDVITEAAMGVQ 190
            ..|::.|..||:.||:.||.::...:.:|:|.|...::...:|::.::|||..||.|.:.|....
 Frog   145 QHRRLITPGFHYDVLKPYVSLISDSTKIMLDELDVYSNKDESVELFQHVSLMTLDSIMKCAFSYH 209

  Fly   191 VNAQNDPDFPYIKALKSVVYIQPDRMFRFSRRYNWLFPLAAPLLHR-QLLSDIRVMHDFTDKVIS 254
            .|.|.|.|..||:|:..:.::...|:..|....|.::.|:.   |. :.....|::|..|||||.
 Frog   210 SNCQTDKDNDYIQAVYDLSWLTQQRIRTFPYHSNLIYFLSP---HGFRFRKACRIVHLHTDKVIG 271

  Fly   255 ERRETVRRAKADGTYRPLSLGDAE-IGSKSQMALLDILLQS-SINNQPLSDADIREEVDTFMFEG 317
            :|::.:.           |..:.| :..|..:..|||||.| ..|.|.||..|:|.|||||||||
 Frog   272 QRKKLLE-----------SKEELEKVQKKRHLDFLDILLCSKDENGQGLSHEDLRAEVDTFMFEG 325

  Fly   318 DDTTSSGVSHALYAIARHPEVQQRIFEELQRVLGPDASAPVTQAQLQDLKYLDCVIKETMRLYPP 382
            .||||||:|..||.:|.|||.||:..||:...||...:  :....|..:.|....|||::|||||
 Frog   326 HDTTSSGISWILYCMATHPEHQQKCREEISEALGERQT--MEWDDLNRMPYTTMCIKESLRLYPP 388

  Fly   383 VPAIGRHAQKELEIGD-KTIPANTSIYLVLYYAHRDANYFPDPLSFRPERFLEDQEQGHNTFAYV 446
            ||::.|...|.:...| :::||...:.|.:|..||:.|.:.||..|.|.||..:.....::.|:|
 Frog   389 VPSVSRELAKPITFHDGRSLPAGMLVSLQIYAIHRNPNVWKDPEIFDPLRFSPENSSKRHSHAFV 453

  Fly   447 PFSAGPKNCIGQKFAVLEMKVLISKVLRFYELLPLGEELKPML---NFILRSASGINVGLR 504
            ||:|||:|||||.||:.||||.::..|:.:||.|  :..||.|   ..:|||.:||:|.|:
 Frog   454 PFAAGPRNCIGQNFAMNEMKVAVALTLKRFELSP--DLSKPPLKQPQLVLRSKNGIHVYLK 512

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d20	NP_647723.2	CYP4	68..501	CDD:410721	159/443 (36%)
cyp4b1.2	NP_001017348.1	CYP4B-like	76..510	CDD:410771	163/459 (36%)