Protein Alignment Cyp4d20 and Cyp26c1

DIOPT Version :10

• Sequence 1: NP_647723.2
• Gene: Cyp4d20 / 38311
• FlyBaseID: FBgn0035344
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: NP_001098671.1
• Gene: Cyp26c1 / 546726
• MGIID: 2679699
• Length: 518
• Species: Mus musculus
• Alignment Length: 513
• Identity: 120/513 - (23%)
• Similarity: 198/513 - (38%)
• Gaps: 98/513 - (19%)

  Fly     4 TLITGALIL-------LLTWDFGRKRQRVLAFEKSAIPGPISIPILGCGLQALHLGAENIIGWV- 60
            ||:...|:|       .|.|...|.....|...|    |.:..|..|   :.||        |:
Mouse    18 TLLCAGLLLGLAQQLWTLRWTLSRDWASTLPLPK----GSMGWPFFG---ETLH--------WLV 67

  Fly    61 -GEKF-----DKYGKTFRFWILGESLIYTKDLQYFETILSSTTLLEKGQLYEYLRPFL-NDGLLV 118
             |.:|     ::||..|:..:||..:|.....:...|||.....|.:.|..:.....| :..||.
Mouse    68 QGSRFHSSRRERYGTVFKTHLLGRPVIRVSGAENVRTILLGEHRLVRSQWPQSAHILLGSHTLLG 132

  Fly   119 STGRKWHARRKIFTHAFHFKVLEHYVEIMDRHSSVMVDNLRKVADGKTAVDMLKYVSLAALDVIT 183
            :.|.....|||:....|....||.:|   .|....:...:|.....:..|.:.:........:..
Mouse   133 AVGEPHRQRRKVLARVFSRSSLEQFV---PRLQGALRREVRSWCAAQRPVAVYQAAKALTFRMAA 194

  Fly   184 EAAMGVQVNAQNDPDFPYIKALKSVVYIQPDRMFRFSRRYNWLFPLAAPLLHRQLLSDIRV---M 245
            ...:|:|::.....:..:                .|.:....||.|...:....|...||.   :
Mouse   195 RILLGLQLDEARCTELAH----------------TFEQLVENLFSLPLDVPFSGLRKGIRARDQL 243

  Fly   246 HDFTDKVISERRETVRRAKADGTYRPLSLGDAEIGSKSQMALLDILLQSSINNQPLSDADIREEV 310
            ::..|:.::|:.:..:.|:.         |||        .||.|.....:.::| |..:::|..
Mouse   244 YEHLDEAVAEKLQEKQTAEP---------GDA--------LLLIINSARELGHEP-SVQELKELA 290

  Fly   311 DTFMFEGDDTTSSGVSHALYAIARHPEVQQRIFEELQ------------RVLG--PDASA--PVT 359
            ...:|....||:|..:..:..:.:||....:|.:||.            |..|  ||...  .::
Mouse   291 VELLFAAFFTTASASTSLILLLLQHPAAITKIQQELSAQGLGRACTCTPRASGSPPDCGCEPDLS 355

  Fly   360 QAQLQDLKYLDCVIKETMRLYPPVPAIGRHAQKELEIGDKTIPANTSIYLVLYYAHRD-----AN 419
            .|.|..|:|:|||:||.:||.|||....|.|.:..|:....||...|:    .|:.||     |.
Mouse   356 LAMLGRLRYVDCVVKEVLRLLPPVSGGYRTALRTFELDGYQIPKGWSV----MYSIRDTHETAAV 416

  Fly   420 YFPDPLSFRPERF-LE--DQEQGHNTFAYVPFSAGPKNCIGQKFAVLEMKVLISKVLR 474
            |...|..|.|||| :|  |.......|.|:||..|.::|:||:.|...:::|..:::|
Mouse   417 YRSPPEGFDPERFGVESGDARGSGGRFHYIPFGGGARSCLGQELAQAVLQLLAVELVR 474

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d20	NP_647723.2	CYP4	68..501	CDD:410721	102/435 (23%)
Cyp26c1	NP_001098671.1	cytochrome_P450	59..504	CDD:477761	109/468 (23%)