Protein Alignment Cyp4d20 and Cyp4a1

DIOPT Version :10

• Sequence 1: NP_647723.2
• Gene: Cyp4d20 / 38311
• FlyBaseID: FBgn0035344
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: NP_787031.1
• Gene: Cyp4a1 / 50549
• RGDID: 68945
• Length: 509
• Species: Rattus norvegicus
• Alignment Length: 534
• Identity: 169/534 - (31%)
• Similarity: 268/534 - (50%)
• Gaps: 86/534 - (16%)

  Fly     6 ITGALILLL-TWDFGRKRQRVL-AFEKSAIPGPISIPILGCGLQALHLGAENIIGWV-------G 61
            :.|.|:||: ...|..:||.:| ||::  .|.|           ..|        |.       |
  Rat    24 VLGLLLLLVKAVQFYLQRQWLLKAFQQ--FPSP-----------PFH--------WFFGHKQFQG 67

  Fly    62 EK--------FDKYGKTFRFWILGES---LIYTKDLQYFETILSSTTLLEKGQLYEYLRPFLNDG 115
            :|        .:.:...|..|..|..   ::|..|  |.:.||..:.....| :|..|.|::..|
  Rat    68 DKELQQIMTCVENFPSAFPRWFWGSKAYLIVYDPD--YMKVILGRSDPKANG-VYRLLAPWIGYG 129

  Fly   116 LLVSTGRKWHARRKIFTHAFHFKVLEHYVEIMDRHSSVMVDNLRKVADGKTAVDMLKYVSLAALD 180
            ||:..|:.|...|::.|.|||:.:|:.||:.|.....:|:|...::|...:::::.:::||..||
  Rat   130 LLLLNGQPWFQHRRMLTPAFHYDILKPYVKNMADSIRLMLDKWEQLAGQDSSIEIFQHISLMTLD 194

  Fly   181 VITEAAMGVQVNAQNDPDF-PYIKALKSV----------VYIQPDRMFRFSRRYNWLFPLAAPLL 234
            .:.:.|.....:.|.|.:: .||:|:.::          ::.|.|.::.||.. ..||..|..|
  Rat   195 TVMKCAFSHNGSVQVDGNYKSYIQAIGNLNDLFHSRVRNIFHQNDTIYNFSSN-GHLFNRACQL- 257

  Fly   235 HRQLLSDIRVMHDFTDKVISERRETVRRAKADGTYRPLSLGDAE-IGSKSQMALLDILLQSSI-N 297
                      .||.||.||..|::.::.|           |:.| :..|.::..|||||.:.: |
  Rat   258 ----------AHDHTDGVIKLRKDQLQNA-----------GELEKVKKKRRLDFLDILLLARMEN 301

  Fly   298 NQPLSDADIREEVDTFMFEGDDTTSSGVSHALYAIARHPEVQQRIFEELQRVLGPDASAPVTQAQ 362
            ...|||.|:|.|||||||||.|||:||||...||:|.|||.|||..||:|.|||..:|  :|...
  Rat   302 GDSLSDKDLRAEVDTFMFEGHDTTASGVSWIFYALATHPEHQQRCREEVQSVLGDGSS--ITWDH 364

  Fly   363 LQDLKYLDCVIKETMRLYPPVPAIGRHAQKELEIGD-KTIPANTSIYLVLYYAHRDANYFPDPLS 426
            |..:.|....|||.:|||||||.|.|.....:...| :::|....:.|.:|..|.:...:|:|..
  Rat   365 LDQIPYTTMCIKEALRLYPPVPGIVRELSTSVTFPDGRSLPKGIQVTLSIYGLHHNPKVWPNPEV 429

  Fly   427 FRPERFLEDQEQGHNTFAYVPFSAGPKNCIGQKFAVLEMKVLISKVLRFYELLPLGEELK-PMLN 490
            |.|.||..|..:  ::.:::|||.|.:||||::||:.||||:::..|..:||||...::. |:..
  Rat   430 FDPSRFAPDSPR--HSHSFLPFSGGARNCIGKQFAMSEMKVIVALTLLRFELLPDPTKVPIPLPR 492

  Fly   491 FILRSASGINVGLR 504
            .:|:|.:||.:.|:
  Rat   493 LVLKSKNGIYLYLK 506

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d20	NP_647723.2	CYP4	68..501	CDD:410721	152/450 (34%)
Cyp4a1	NP_787031.1	CYP4B-like	71..504	CDD:410771	152/462 (33%)