DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cyp4d20 and Cyp313b1

DIOPT Version :9

Sequence 1:	NP_647723.2	Gene:	Cyp4d20 / 38311	FlyBaseID:	FBgn0035344	Length:	510	Species:	Drosophila melanogaster
Sequence 2:	NP_001287239.1	Gene:	Cyp313b1 / 41019	FlyBaseID:	FBgn0037601	Length:	502	Species:	Drosophila melanogaster

Alignment Length:	485	Identity:	129/485 - (26%)
Similarity:	237/485 - (48%)	Gaps:	41/485 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 LLLTWDF---GRKRQRVLAFEKSAIPGPISIPILGCGLQALHLGAENIIGWVGEKFDKYGKTFRF 73
            |||.|.:   .|:|...:|::   :.|||..|::|.|||.::  .|..:.::.....::...|..
  Fly    11 LLLAWLYFLWSRRRYYKVAWQ---LRGPIGWPLIGMGLQMMN--PETFLQYMDGLSRQFKAPFIS 70

  Fly    74 WILGESLIYTKDLQYFETILSSTTLLEKGQLYEYLRPFLNDGLLVSTGRKWHARRKIFTHAFHFK 138
            |:.....:|..|....|.||:||....||..|.::...:.|||..|:..:||..|::...||..:
  Fly    71 WMGTSCFLYINDPHSVEQILNSTHCTNKGDFYRFMSSAIGDGLFTSSSPRWHKHRRLINPAFGRQ 135

  Fly   139 VLEHYVEIMDRHSSVMVD--NLRKVADGKTAVDMLKYVSLAALDVITEAAMGVQVNAQNDPDFPY 201
            :|.:::.|.:..:.|::.  .|..|..|| .:::.:.:....|:...:..||.::|.|:|.....
  Fly   136 ILSNFLPIFNAEAEVLLQKLELEGVQHGK-RLEIYQILKKIVLEAACQTTMGKKMNFQHDGSLCI 199

  Fly   202 IKALKSVVYIQPDRMFRFSRRYNWLFPLAAPLLHRQ------LLSDIRVMHDFTDKVISERRETV 260
            .||...:..:...||..     .||:|   .|::|:      ....:.::..|.::::    |.:
  Fly   200 FKAYNGLTEVCVKRMLS-----PWLYP---DLIYRRSGLFRLQQKVVGILFGFIEQLL----EPI 252

  Fly   261 RRAKADGTYRPLSLGDAEIGSKSQMALLDILLQSSINNQPLSDADIREEVDTFMFEGDDTTSSGV 325
            ....|..:.......:.|:..||:...:: .::..:....||..|:|:|.:..:....:|||:.:
  Fly   253 VSVVAANSNPDQQRSEMEMRGKSKAIFIE-QVREHVERGQLSWQDVRDEANVTIAATFETTSTAL 316

  Fly   326 SHALYAIARHPEVQQRIFEELQRVLGPDASAPVTQAQLQDLKYLDCVIKETMRLYPPVPAIGRHA 390
            ...:..:|.||..|:::.:||...|.|  |..:...|||.|:|.:.||.|.|||:.|||.:.|.|
  Fly   317 YFTILCLAMHPCYQEKLHKELVTELPP--SGDINLEQLQRLEYTEMVINEAMRLFAPVPMVLRSA 379

  Fly   391 QKELEI----GDKTIPANTSIYLVLYYAHRDANYFPDPLS--FRPE-RFLEDQEQGHNTFAYVPF 448
            .:::::    |:..||..|.|.:.:|...||...: .|||  :.|: .|..|..|.| .||:|||
  Fly   380 DQDIQLKRGDGEFLIPRGTQIGIDIYNMQRDERVW-GPLSRTYNPDAHFGLDSPQRH-AFAFVPF 442

  Fly   449 SAGPKNCIGQKFAVLEMKVLISKVLRFYEL 478
            :.|.:.|||.::|.:.||:|::::.|.|.:
  Fly   443 TKGLRMCIGYRYAQMLMKLLLARIFRSYRI 472

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d20	NP_647723.2	p450	34..493	CDD:278495	122/460 (27%)
Cyp313b1	NP_001287239.1	p450	33..474	CDD:299894	122/460 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	101	1.000	Domainoid score	I1781
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	170	1.000	Inparanoid score	I1543
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X23
	5	4.970