Protein Alignment Cyp4d20 and Cyp6a8

DIOPT Version :10

• Sequence 1: NP_647723.2
• Gene: Cyp4d20 / 38311
• FlyBaseID: FBgn0035344
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: NP_523749.2
• Gene: Cyp6a8 / 36666
• FlyBaseID: FBgn0013772
• Length: 506
• Species: Drosophila melanogaster
• Alignment Length: 549
• Identity: 131/549 - (23%)
• Similarity: 236/549 - (42%)
• Gaps: 120/549 - (21%)

  Fly     9 ALILLLTWDFGRKRQRVLAFEKSAIPGPISIPILGCGLQALHLGAENI-----IGWVGEKFDKYG 68
            ||:.:||:...||   :..|::..||           ..|.||...|:     ...:.|.|..:.
  Fly    13 ALLAILTYYIHRK---LTYFKRRGIP-----------FVAPHLIRGNMEELQKTKNIHEIFQDHY 63

  Fly    69 KTFR--------FWILGESLIYTKDLQYFETIL--SSTTLLEKGQLYEYLRPFLNDGLLVSTGRK 123
            ..||        |:.......:..||:..:.||  ..:....||..|......::..|....|.:
  Fly    64 NKFRESKAPFVGFFFFQSPAAFVIDLELAKQILIKDFSNFSNKGIFYNEKDDPISAHLFNLDGAQ 128

  Fly   124 WHARRKIFTHAF---HFKVL-EHYVEIMDRHSSVMVDNLRKVADGKTAVDMLKYVSLAALDVITE 184
            |...|...:..|   ..|:: ...|.:.:...:||.:.:.|    .:.:::...|:...:|||..
  Fly   129 WRLLRNKLSSTFTSGKMKLMYPTVVSVANEFMTVMHEKVPK----NSVLEIRDLVARFTVDVIGT 189

  Fly   185 AAMGVQVNAQND--PDFPYIKALKSVVYIQPDRMFRFSRRYNWL---FPLAAPLLHRQLLSDIRV 244
            .|.|:|.|:..|  .:|.|. ..:|:|          .:|:..|   |..:.|.|.|: |..:|.
  Fly   190 CAFGIQCNSLRDEKAEFLYF-GKRSLV----------DKRHGTLLNGFMRSYPKLARK-LGMVRT 242

  Fly   245 ---MHDFTDKVISE-----RRETVRRAKADGTYRPLSLGDAEIGSKSQMALLDILLQSSINNQ-- 299
               :.:|..::::|     .:|.::|..                      .:|:|::  :.||
  Fly   243 APHIQEFYSRIVTETVAVREKEHIKRND----------------------FMDMLIE--LKNQKE 283

  Fly   300 -PLSDADI-----REEV--DTFMF--EGDDTTSSGVSHALYAIARHPEVQQRIFEELQRVLGPDA 354
             .|.:.|:     .|||  ..|:|  .|.:|:||.:..|||.:|::|::|.::..|::.|: ...
  Fly   284 MTLENGDVVRGLTMEEVLAQAFVFFIAGFETSSSTMGFALYELAKNPDIQDKVRAEVEEVI-EQH 347

  Fly   355 SAPVTQAQLQDLKYLDCVIKETMRLYPPVPAIGRHAQKE----------LEIGDKTIPANTSIYL 409
            ....|....:|||||:.|:.||:|||..||.:.|.|.|.          :|.|...|..:::|
  Fly   348 DQNFTYECTKDLKYLNQVLDETLRLYTIVPNLDRMAAKRYVVPGHPNFVIEAGQSVIIPSSAI-- 410

  Fly   410 VLYYAHRDANYFPDPLSFRPERFLEDQEQGHNTFAYVPFSAGPKNCIGQKFAVLEMKVLISKVLR 474
                 |.|.:.:|:|..||||||..::..|..:.|::||..||:||||.:|..::.::.::.::|
  Fly   411 -----HHDPSIYPEPFEFRPERFSPEESAGRPSVAWLPFGDGPRNCIGLRFGQMQARIGLALLIR 470

  Fly   475 FYELLPLGEELKPML----NFILRSASGI 499
            .::.....:...|::    :|:|....||
  Fly   471 NFKFSTCSKTPNPLVYDPKSFVLGVKDGI 499

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d20	NP_647723.2	CYP4	68..501	CDD:410721	116/485 (24%)
Cyp6a8	NP_523749.2	CYP6-like	70..500	CDD:410679	114/478 (24%)