Protein Alignment Cyp4d20 and Cyp4e2

DIOPT Version :10

• Sequence 1: NP_647723.2
• Gene: Cyp4d20 / 38311
• FlyBaseID: FBgn0035344
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: NP_477117.2
• Gene: Cyp4e2 / 35822
• FlyBaseID: FBgn0014469
• Length: 526
• Species: Drosophila melanogaster
• Alignment Length: 554
• Identity: 200/554 - (36%)
• Similarity: 298/554 - (53%)
• Gaps: 77/554 - (13%)

  Fly     1 MWLTL-ITGALILLL-------TWDFGRKRQRVLAFEKSAIPGPISIPILGCGLQALHLG----- 52
            ||..| |..||.|||       |:    :|:|||    :...||..:|::|   .|..:|
  Fly     1 MWFVLYIFLALPLLLVAYLELSTF----RRRRVL----NKFNGPRGLPLMG---NAHQMGKNPSE 54

  Fly    53 -AENIIGWVGEKFDKYGK-TFRFWILGESLIYTKDLQYFETILSSTTLLEKGQLYEYLRPFLNDG 115
             .:.:..|    :.:||| .|.|||...|.:.....:|.|.||||.||:.|..:|:...|:|..|
  Fly    55 ILDTVFSW----WHQYGKDNFVFWIGTYSNVLVTSSKYLEFILSSQTLITKSDIYQLTHPWLGLG 115

  Fly   116 LLVSTGRKWHARRKIFTHAFHFKVLEHYVEIMDRHSSVMVDNLRKVADGKTAVDMLKYVSLAALD 180
            ||.|||.|||..||:.|.||||.:|:.:.|:|:.:|:..:.:|:.||.|....|..:......||
  Fly   116 LLTSTGSKWHKHRKMITPAFHFNILQDFHEVMNENSTKFIKHLKTVAAGDNIFDFQEQAHYLTLD 180

  Fly   181 VITEAAMGVQVNAQNDPDFPYIKALKSVVYIQPDRMFRFSRRYNWLFPLAA--PLLHRQLLSDIR 243
            ||.:.||||.:||..:.....::|.|.:.|....|.|...:|...|:.||.  |...|.|    :
  Fly   181 VICDTAMGVSINAMENRSSSIVQAFKDMCYNINMRAFHPLKRNELLYRLAPDYPAYSRTL----K 241

  Fly   244 VMHDFTDKVISERRETVRRAKADGTYRPLSLGDAEIGSKSQMALLDILLQSSINNQPLSDADIRE 308
            .:.|||:::|::|.|    |...|.   :|....:..::.:||.||.||.|:|:.:||:..::.|
  Fly   242 TLQDFTNEIIAKRIE----AHKSGA---VSTNAGDEFTRKKMAFLDTLLSSTIDGRPLNSKELYE 299

  Fly   309 EVDTFMFEGDDTTSSGVSHALYAIARHPEVQQRIFEELQRVLG-PDASAPVTQAQLQDLKYLDCV 372
            ||.||||||.|||:||||.|:|.::||.:.|:::|:|.:.|:| .:.....|..::..:||||..
  Fly   300 EVSTFMFEGHDTTTSGVSFAVYLLSRHQDEQRKLFKEQREVMGNSELGRDATFQEISQMKYLDLF 364

  Fly   373 IKETMRLYPPVPAIGRHAQKELEIGDKTIPANTSIYLVLYYAHRDANYFPDPLSFRPERFLEDQE 437
            |||..|:||.||.|||..:|:..|....:|..|::.|.|.....:...|.||..|||||| |.::
  Fly   365 IKEAQRVYPSVPFIGRFTEKDYVIDGDLVPKGTTLNLGLVMLGYNEKVFKDPHKFRPERF-ELEK 428

  Fly   438 QGHNTFAYVPFSAGPKNCIGQKFAVLEMKVLISKVLRFYELLPLGEEL----------------- 485
            .|  .|.||||||||:||||||||:||:|.::||::|.:|:||..:||
  Fly   429 PG--PFEYVPFSAGPRNCIGQKFALLEIKTVVSKIIRNFEVLPALDELVSKDGYISTTIGLPDAE 491

  Fly   486 -----------KPMLNFI--LRSASGINVGLRPR 506
                       .|:|:.:  |:|.:|:.:.|:.|
  Fly   492 RKKRDPYRHKYDPILSAVLTLKSENGLYIRLKER 525

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d20	NP_647723.2	CYP4	68..501	CDD:410721	176/466 (38%)
Cyp4e2	NP_477117.2	CYP4	68..520	CDD:410721	175/465 (38%)