Protein Alignment Cyp4d20 and Cyp4e3

DIOPT Version :9

• Sequence 1: NP_647723.2
• Gene: Cyp4d20 / 38311
• FlyBaseID: FBgn0035344
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: NP_523527.1
• Gene: Cyp4e3 / 34291
• FlyBaseID: FBgn0015035
• Length: 526
• Species: Drosophila melanogaster
• Alignment Length: 547
• Identity: 195/547 - (35%)
• Similarity: 301/547 - (55%)
• Gaps: 60/547 - (10%)

  Fly     1 MWLTLITGALILLLTWDF-----GRKRQRVLAFEKSAIPGPISIPILGCGLQALHLGAENIIGWV 60
            |||.::...::.|:|..:     .::||.:..|.     ||..:||||   .|..:| :|....:
  Fly     1 MWLAVLALLVLPLITLVYFERKASQRRQLLKEFN-----GPTPVPILG---NANRIG-KNPAEIL 56

  Fly    61 GEKFD---KYGK-TFRFWILGESLIYTKDLQYFETILSSTTLLEKGQLYEYLRPFLNDGLLVSTG 121
            ...||   .||| .|.|||...|.|...:.:..|.||:|..|::|..:|:.|.|:|..|||.|.|
  Fly    57 STFFDWWYDYGKDNFLFWIGYSSHIVMTNPKQLEYILNSQQLIQKSTIYDLLHPWLGHGLLTSFG 121

  Fly   122 RKWHARRKIFTHAFHFKVLEHYVEIMDRHSSVMVDNLRKVADGKTAVDMLKYVSLAALDVITEAA 186
            .|||..||:.|.:|||.:|:.:.|:|:.:|:..:..|:|.:.|.|.:|..::.:...||||.:.|
  Fly   122 SKWHKHRKMITPSFHFNILQDFHEVMNENSAKFMTQLKKASAGDTIIDFQEHANYLTLDVICDTA 186

  Fly   187 MGVQVNAQNDPDFPYIKALKSVVYIQPDRMFRFSRRYNWLFPLAAPLLHRQLLSDIRVMHDFTDK 251
            |||.:||....|...::|.:.:.|....|.|...:|.|.:|.|.......|  ..::.:.|||..
  Fly   187 MGVPINAMEQRDSSIVQAFRDMCYNINMRAFHPFKRSNRVFSLTPEFSAYQ--KTLKTLQDFTYD 249

  Fly   252 VISERRETVRRAKADGTYRPLSLGDAEIGSKSQMALLDILLQSSINNQPLSDADIREEVDTFMFE 316
            :|.:|...::...:...:.| ||      .:.:||.||.||.|:|:.:||:..:|.|||.|||||
  Fly   250 IIEKRVYALQNGGSKEDHDP-SL------PRKKMAFLDTLLSSTIDGRPLTRQEIYEEVSTFMFE 307

  Fly   317 GDDTTSSGVSHALYAIARHPEVQQRIFEELQRVLGPDASAPVTQAQLQDLKYLDCVIKETMRLYP 381
            |.|||:||||.::|.::|||:||::::.|...|:|.|.:..|:..::..:||||..|||..|:||
  Fly   308 GHDTTTSGVSFSVYLLSRHPDVQRKLYREQCEVMGHDMNRSVSFQEIAKMKYLDLFIKEAQRVYP 372

  Fly   382 PVPAIGRHAQKELEIGDKTIPANTSIYLVLYYAHRDANYFPDPLSFRPERFLEDQEQGHNTFAYV 446
            .||.|||:..|:.:|....:|..|::.|.|.....:...|.||..||||||   :|:....|.|:
  Fly   373 SVPFIGRYCDKDYDINGSIVPKGTTLNLALILLGYNDRIFKDPHHFRPERF---EEEKPAPFEYL 434

  Fly   447 PFSAGPKNCIGQKFAVLEMKVLISKVLRFYELLPLGEEL-------------------------- 485
            ||||||:||||||||:||:|.:||||:|.:|:||..:||
  Fly   435 PFSAGPRNCIGQKFALLELKTVISKVVRSFEVLPAVDELVSTDGRLNTYLGLAPDEKLKREAGRH 499

  Fly   486 --KPMLNFI--LRSASGINVGLRPRKA 508
              .|:|:.:  |:|.:|:::.||.|::
  Fly   500 KYDPILSAVLTLKSDNGLHLRLRERRS 526

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d20	NP_647723.2	p450	34..493	CDD:278495	181/492 (37%)
Cyp4e3	NP_523527.1	p450	35..468	CDD:278495	175/448 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45449023
Domainoid	1	1.000	101	1.000	Domainoid score	I1781
eggNOG	1	0.900	-	-		E33208_3B9GY
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	170	1.000	Inparanoid score	I1543
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D10482at33392
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	1	1.000	-	-		mtm8393
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24291
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X23
	10	9.900