Protein Alignment Cyp4d20 and Cyp4a8

DIOPT Version :9

• Sequence 1: NP_647723.2
• Gene: Cyp4d20 / 38311
• FlyBaseID: FBgn0035344
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: XP_038965258.1
• Gene: Cyp4a8 / 266674
• RGDID: 628846
• Length: 510
• Species: Rattus norvegicus
• Alignment Length: 517
• Identity: 159/517 - (30%)
• Similarity: 262/517 - (50%)
• Gaps: 48/517 - (9%)

  Fly     4 TLITGALILLLTWDFGRKRQRVLAFEKSAIPGPISIPILGCGLQALHLGAENIIGWVGEKF-DKY 67
            |::|..|:|..|..|...|:.:|...:. .|.|.|....|..|..|          |.::| |..
  Rat    23 TVLTVLLLLFKTAQFYLHRRWLLRATQQ-FPSPPSHWFFGHKLSFL----------VDQEFQDIL 76

  Fly    68 GKTFRF------WILGESL-IYTKDLQYFETILSSTTLLEKGQLYEYLRPFLNDGLLVSTGRKWH 125
            .:...|      |:.|.:: |...|..|.:.||..:. .:....|.:|.|::..|||:..|:.|.
  Rat    77 TRVKNFPSACPQWLWGSNVRIQVYDPDYMKLILGRSD-PKSHHSYRFLAPWIGYGLLLLNGQTWF 140

  Fly   126 ARRKIFTHAFHFKVLEHYVEIMDRHSSVMVDNLRKVADGKTAVDMLKYVSLAALDVITEAAMGVQ 190
            ..|::.|.|||:..|:.||.||.....:|:|...::....:.:::.::::|..||.|.:.|...:
  Rat   141 QHRRMLTPAFHYDTLKPYVGIMADSVRIMLDKWEQIVGQDSTLEIFQHITLMTLDTIMKCAFSQE 205

  Fly   191 VNAQNDPDF-PYIKALKSVVYIQPDRMFRFSRRYNWLFPLAAPLLHRQLLSDIRVMHDFTDKVIS 254
            .:.|.|..: .||||::.:..:...|:.....:.:.::.|::.  .|:..|..::.|:.||:||.
  Rat   206 GSVQLDRKYKSYIKAVEDLNNLSFFRIRNIFHQNDIIYSLSSN--GRKARSAWQLAHEHTDQVIK 268

  Fly   255 ERRETVRRAKADGTYRPLSLGDAE----IGSKSQMALLDILLQSSI-NNQPLSDADIREEVDTFM 314
            .|:              ..|.|.|    :..|.::..|||||.:.| |...|||.|:|.||||||
  Rat   269 SRK--------------AQLQDEEELQKVKQKRRLDFLDILLFARIENGSSLSDKDLRAEVDTFM 319

  Fly   315 FEGDDTTSSGVSHALYAIARHPEVQQRIFEELQRVLGPDASAPVTQAQLQDLKYLDCVIKETMRL 379
            |||.|||:||:|...||:|.:||.||...:|:|.:||..||  :|...|..:.|....|||.:|:
  Rat   320 FEGHDTTASGISWIFYALATNPEHQQGCRKEIQSLLGDGAS--ITWDDLDKMPYTTMCIKEALRI 382

  Fly   380 YPPVPAIGRHAQKELEIGD-KTIPANTSIYLVLYYAHRDANYFPDPLSFRPERFLEDQEQGHNTF 443
            ||||.|:.|.....:...| :::|...::.|..|..|.:...:|:|..|.|.||.  .|...::.
  Rat   383 YPPVTAVSRMLSTPVTFPDGRSLPKGITVMLSFYGLHHNPTVWPNPEVFDPYRFA--PESSRHSH 445

  Fly   444 AYVPFSAGPKNCIGQKFAVLEMKVLISKVLRFYELLPLGEELK-PMLNFILRSASGINVGLR 504
            :::|||.|.:||||::||:.|:||.::..|..:||||....:. |:...:|:|.:||.:.|:
  Rat   446 SFLPFSGGARNCIGKQFAMNELKVAVALTLLRFELLPDPTRIPIPIPRLVLKSKNGIYLRLK 507

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d20	NP_647723.2	p450	34..493	CDD:278495	146/474 (31%)
Cyp4a8	XP_038965258.1	CYP4B-like	72..505	CDD:410771	143/453 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166348495
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3B9GY
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.750