Protein Alignment Cyp4d20 and erg11

DIOPT Version :9

• Sequence 1: NP_647723.2
• Gene: Cyp4d20 / 38311
• FlyBaseID: FBgn0035344
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: NP_592990.1
• Gene: erg11 / 2542599
• PomBaseID: SPAC13A11.02c
• Length: 495
• Species: Schizosaccharomyces pombe
• Alignment Length: 508
• Identity: 112/508 - (22%)
• Similarity: 201/508 - (39%)
• Gaps: 63/508 - (12%)

  Fly     1 MWLTLITGALILLLTWDFGRKRQRVLAFEKSAIPGPIS---IPILGCGLQALHLGAENIIGWVGE 62
            |..:|::..|.:.|.|..|....: |....|..| ||.   ||.:|   .|:..|.:..: :..|
pombe     1 MAFSLVSILLSIALAWYVGYIINQ-LTSRNSKRP-PIVFHWIPFVG---SAVAYGMDPYV-FFRE 59

  Fly    63 KFDKYGKTFRFWILGESLIYTKDLQYFETILSSTTL-LEKGQLYEYLRP--FLNDGLLVSTGRKW 124
            ...|||..|.|..:|..:.....:|..:.:.:.... |...:.|.:|..  |..|.:.......:
pombe    60 CRAKYGDVFTFVCMGRKMTAFLGVQGNDFLFNGKLADLNAEEAYSHLTTPVFGKDVVYDIPNHVF 124

  Fly   125 HARRKIFTHAFHFKVLEHYVEIMDRHSSVMVDNLRKVADGKTAV-DMLKYVSLAALDVITEAAMG 188
            ...:|.......|.....||.::.......:........||..| |:||.:.:..:...:....|
pombe   125 MEHKKFIKSGLGFSQFRSYVPLILNEMDAFLSTSPDFGPGKEGVADLLKTMPVMTIYTASRTLQG 189

  Fly   189 VQVNAQNDPDFPYIKALKSVVYIQPDRMFRFSRRYNWLFP-LAAPLLHRQLLSDIRVMHDFTDKV 252
            .:|....|..|       :.:|...|:.|   ...|::|| |..|...|:..:. ::|.....|:
pombe   190 AEVRKGFDAGF-------ADLYHDLDQGF---SPVNFVFPWLPLPRNRRRDRAH-KIMQKTYLKI 243

  Fly   253 ISERRETVRRAKADGTYRPLSLGDAEIGSKSQMALLDILLQSSINNQPLSDADIREEVDTFMFEG 317
            |.:||.:......|..:..:|.                   ...:.:||.:.:|...:...:..|
pombe   244 IKDRRSSTENPGTDMIWTLMSC-------------------KYRDGRPLKEHEIAGMMIALLMAG 289

  Fly   318 DDTTSSGVSHALYAIARHPEVQQRIFEELQRVLGPDASAPVTQAQLQDLKYLDCVIKETMRLYPP 382
            ..|:::.:...|..:...||:.:.::||.:||:|.:......  |.:|:..|:.||:||:||:||
pombe   290 QHTSAATIVWVLALLGSKPEIIEMLWEEQKRVVGENLELKFD--QYKDMPLLNYVIQETLRLHPP 352

  Fly   383 VPAIGRHAQKELEI-GDK-TIPANTSIYLVLYYAHRDANYFPDPLSFRPERFLEDQEQGHN---- 441
            :.:..|..:::|.: |.| .||||..:.........:..||.....|.|:|:.:...:..|
pombe   353 IHSHMRKVKRDLPVPGSKIVIPANNYLLAAPGLTATEEEYFTHATDFDPKRWNDRVNEDENAEQI 417

  Fly   442 -----------TFAYVPFSAGPKNCIGQKFAVLEMKVLISKVLRFYELLPLGE 483
                       ...|:||.||...|||::||.:.:..:|||.:..|....:|:
pombe   418 DYGYGLVTKGAASPYLPFGAGRHRCIGEQFAYMHLSTIISKFVHDYTWTLIGK 470

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d20	NP_647723.2	p450	34..493	CDD:278495	104/475 (22%)
erg11	NP_592990.1	CypX	28..495	CDD:225035	105/480 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	101	1.000	Domainoid score	I1781
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	102	1.000	Inparanoid score	I1639
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.960