Protein Alignment Cyp4d20 and Cyp2ab1

DIOPT Version :10

• Sequence 1: NP_647723.2
• Gene: Cyp4d20 / 38311
• FlyBaseID: FBgn0035344
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: XP_017172441.1
• Gene: Cyp2ab1 / 224044
• MGIID: 3644957
• Length: 459
• Species: Mus musculus
• Alignment Length: 507
• Identity: 110/507 - (21%)
• Similarity: 195/507 - (38%)
• Gaps: 137/507 - (27%)

  Fly    67 YGKTFRFWILGESLIYTKDLQYFETILSSTTLLEKGQLYEYLRPFLND-----GLLVSTGRKWHA 126
            :|..|..|:....::.....:..:..|.|.:....|:   .|.||..|     |::.|.|..|..
Mouse    23 HGSVFTVWLGSTPIVVLSGFRAVKEALVSNSEQFSGR---PLTPFFRDLFGEKGVICSNGLTWRQ 84

  Fly   127 RRKIFTHAFHFKVLEHYVEIMDRHSSVMVDNLRKVADGKTAVDM-LKYVSLAALDVITEAAMGVQ 190
            :|:.                       .:..||::..||.|::: |::          |||...:
Mouse    85 QRRF-----------------------CLTTLRELGLGKQALEVQLQH----------EAAELAK 116

  Fly   191 VNAQN-----DPDFPYIKALKSVV--------YIQPDRMF-----------RFS----RRYNWLF 227
            |..|.     ||..|.|::...|:        ::..:.:|           .|:    ||...:|
Mouse   117 VFLQEEGRAFDPQIPIIRSTTRVIGTLVFGHHFLSEEPIFLELIQAINLGLAFASTIWRRLYDMF 181

  Fly   228 P-----LAAPLLHRQLLSDIRVMHDFTDKVISERRETVRRAKADGTYRPLSLG------DAEIGS 281
            |     |:.|  |:::......:..|....|.  |..:|.|:|...:....|.      |..:.:
Mouse   182 PWALRHLSGP--HQKIFQYHEAVRGFIRHEII--RHKLRTAEAPKDFINCYLSQITKAIDDPVST 242

  Fly   282 KSQMALLDILLQSSINNQPLSDADIREEVDTFMFEGDDTTSSGVSHALYAIARHPEVQQRIFEEL 346
            .|:..|:.::                  :|.|: .|.|||::.:..||..:..|..:|:|:.:||
Mouse   243 FSEENLIQVV------------------IDLFL-GGTDTTATTLHWALIYLVHHRAIQERVQQEL 288

  Fly   347 QRVLGPDASAPVTQAQLQDLKYLDCVIKETMRLYPPVPAIG--RHAQKELEIGDKTIPANT---- 405
            ..:||  |:..:.....:.|.|...|:.|..|| ..|.|:|  |.......:....:|..|
Mouse   289 DEMLG--AAQTICYEDRERLPYTRAVLHEVQRL-SSVVAVGAVRQCVTSTWMHGYYVPKGTIILP 350

  Fly   406 SIYLVLYYAHRDANYFPDPLSFRPERFLEDQEQGHNTFAYVPFSAGPKNCIGQKFAVLEMKVLIS 470
            ::..|||    |...:..|..|.|..||:.........|::|||||.:.|.|::.|.:|:.::.:
Mouse   351 NLASVLY----DPECWESPHQFNPGHFLDKDGNFVANEAFLPFSAGHRVCPGEQLARMELFLMFA 411

  Fly   471 KVLRFYEL-LPLGEE-----------LKPM---LNFILRSASGINVGLRPRK 507
            .:||.::. ||.|.:           |:|.   :..:||.:|     |.||:
Mouse   412 TLLRTFQFQLPEGSQDLGLEYVFGGTLQPQPQKICAVLRQSS-----LSPRE 458

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d20	NP_647723.2	CYP4	68..501	CDD:410721	107/498 (21%)
Cyp2ab1	XP_017172441.1	CYP2AB1-like	23..445	CDD:410760	104/487 (21%)