Protein Alignment Cyp4d20 and cyp-13A2

DIOPT Version :10

• Sequence 1: NP_647723.2
• Gene: Cyp4d20 / 38311
• FlyBaseID: FBgn0035344
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: NP_496109.1
• Gene: cyp-13A2 / 188360
• WormBaseID: WBGene00011676
• Length: 515
• Species: Caenorhabditis elegans
• Alignment Length: 534
• Identity: 126/534 - (23%)
• Similarity: 216/534 - (40%)
• Gaps: 107/534 - (20%)

  Fly    30 KSAIPGPISIPILGCGLQALHLGAENIIGWVGEKFDKYGKTFRFWILGESLIYTKDLQYFETILS 94
            :..:.||...|.:|.....|......:|. :||...||||.:.         ||...|      .
 Worm    30 RKGVKGPRGRPFVGVLDVLLEHETPGLIK-LGEWTKKYGKVYG---------YTDGTQ------R 78

  Fly    95 STTLLEKGQLYE-YLRPFLN---------DG---------LLVSTGRKWHARRKIFTHAFHFKVL 140
            :..:.:...::| :::.|.|         .|         ||.:.|.:|...|.|.:.:|....|
 Worm    79 TLVVADPAMVHEIFVKQFDNFYGRKLNPIQGNPEKEQRVHLLAAQGYRWKRLRTISSQSFSNASL 143

  Fly   141 EHYVEIMDRHSSVMVDNLRKVADGKTAVDMLKYVSLAALDVITEAAMGVQ---------VNAQND 196
            :.....::..:..::.::.|...|...:|||::.....:|||...|||..         ||...:
 Worm   144 KKMKRTVEDSALELLRHIEKQTAGGEQIDMLRFYQEYTMDVIGRFAMGQTDSMMFKNPIVNVVRE 208

  Fly   197 PDFPYIKALKSVVYIQPDRMFRFSRRYNWLFPLAAPLLHRQLLSDI---RVM------------- 245
            ......|.|..:..:.|. :.:|.|...:.||.........::.|:   |:.
 Worm   209 IFCGSRKNLMLICQVFPP-IGQFIRDLTFKFPRIPAFKLYSIMQDVVAARIAQREREKGAESGEP 272

  Fly   246 HDFTDKVISERRETV---RRAKADGTYRPLSLGDAEIGSKSQMALLDILLQSSINNQPLSDADIR 307
            .||.|..:..|.:.|   ..|:.|.:.|.|.:                       .:.||..::.
 Worm   273 QDFIDLFLDARSDDVDFSAEAREDFSKRNLKI-----------------------TKELSADEVV 314

  Fly   308 EEVDTFMFEGDDTTSSGVSHALYAIARHPEVQQRIFEELQRVLGPDASAPVTQAQLQDLKYLDCV 372
            .:...|:..|.|||:..:|:..|.:|.:|::|:::.||:.|..|   ::.|...:|..|||:|||
 Worm   315 GQCFLFLIGGFDTTALSLSYVTYLLAVNPKIQEKVIEEIAREFG---TSEVEFEKLGRLKYMDCV 376

  Fly   373 IKETMRLYPPVPAI--GRHAQKELEIGDKTIPANTSIYLVLYYAHRDANYF-PDPLSFRPERFLE 434
            |||.:||| |:.:|  .|...|...:....|.|...:.:..:..|.|...: .|...|:|||:..
 Worm   377 IKEALRLY-PLASISNSRKCMKTTTVNGVKIEAGVYVQMDTWSLHYDPELWGEDVKEFKPERWST 440

  Fly   435 DQEQGHNTFAYVPFSAGPKNCIGQKFAVLEMKVLISKVLRFYEL-------LPLGEELKPMLNFI 492
            |:...|.. ||:||..||:.|||.:.|::|.|:|::.:|:.|..       :||     .::...
 Worm   441 DEPLEHKG-AYLPFGLGPRQCIGMRLAIMEQKILLTHLLKNYTFETGNKTRIPL-----KLVGSA 499

  Fly   493 LRSASGINVGLRPR 506
            ..|...:.|.||||
 Worm   500 TTSPEDVFVHLRPR 513

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d20	NP_647723.2	CYP4	68..501	CDD:410721	111/489 (23%)
cyp-13A2	NP_496109.1	CYP3A-like	65..508	CDD:410678	113/491 (23%)