Protein Alignment Cyp4d20 and cyp-13A10

DIOPT Version :10

• Sequence 1: NP_647723.2
• Gene: Cyp4d20 / 38311
• FlyBaseID: FBgn0035344
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: NP_496085.3
• Gene: cyp-13A10 / 174522
• WormBaseID: WBGene00014254
• Length: 519
• Species: Caenorhabditis elegans
• Alignment Length: 528
• Identity: 131/528 - (24%)
• Similarity: 222/528 - (42%)
• Gaps: 106/528 - (20%)

  Fly     4 TLITGAL-ILLLTWDFGRKRQRVLAFEKSAIPGPISIPILGC---GLQALHLGAENIIGWVGEKF 64
            ||..|.: ..|..|.:.|:|         .||||:..|::|.   .|::.:.....|..|.....
 Worm    10 TLFIGFISYYLWIWTYWRRR---------GIPGPLGYPLVGSFPKTLKSEYPQYLQIRDWTKLYG 65

  Fly    65 DKYGKTFRFWILGESLIYTKDLQYFETILSSTTLLEKGQLYEY-------LRPFLND-------G 115
            ..||.|       |..|.|       .|:|...::.:..:.:|       |.|...|       .
 Worm    66 PIYGYT-------EGTIKT-------LIVSDIDIVRQIFVEQYDNFYGRKLNPIQGDPEKDERTN 116

  Fly   116 LLVSTGRKWHARRKIFTHAFHFKVLEHYVEIMDRHSSVMVDNLRKVADGKTAVDMLKYVSLAALD 180
            |..:.|.:|...|.|.:..|....|......::..:..::.::.:.......:|||::.....:|
 Worm   117 LFSAQGFRWKRLRAISSPTFSNNSLRKINVTVEDSAMELLRHIEEQTSEGQQIDMLQFYQEFTMD 181

  Fly   181 VITEAAMGVQVNAQ--NDPDFPYIKAL-----KSV-----VYIQPDRMFRFSRRYNWLFPL--AA 231
            .|...||| |.::|  .:|...:::|:     |.:     |:....::|||   :...|||  ||
 Worm   182 TIGRIAMG-QTDSQMFKNPLLKFVRAIFGDNRKHIPLIGGVFPTLAQVFRF---FMLKFPLLGAA 242

  Fly   232 PLLH-------------------RQLLSDIRVMHDFTDKVISERRETVRRAKADGTYRPLSLGDA 277
            ..:|                   |:...:|....||.|..:..|.:.|...:.:.       ||.
 Worm   243 NFIHVNKTVVTAVQNRIDQRENDRKNGIEIGEPQDFIDLFLEARADDVEHFQENN-------GDF 300

  Fly   278 EIGSKSQMALLDILLQSSINNQPLSDADIREEVDTFMFEGDDTTSSGVSHALYAIARHPEVQQRI 342
               ||:          ||..|:.|:..:|..:...|:..|.|||:..:|:..:.:|.|||||:::
 Worm   301 ---SKT----------SSYGNRQLTTQEIVGQCLVFLIAGFDTTALSLSYTTFLLATHPEVQKKL 352

  Fly   343 FEELQR-VLGPDASAPVTQAQLQDLKYLDCVIKETMRLYP-PVPAIGRHAQKELEIGDKTIPANT 405
            .||::| .:.|..|..    .|..|||:||:||||:|||| ...|..|...:..::|:..:...|
 Worm   353 QEEIERECIEPSISFD----HLSKLKYMDCIIKETLRLYPLGTMANSRRCMRATKLGNVEVEVGT 413

  Fly   406 SIYLVLYYAHRDANYF-PDPLSFRPERFLEDQ-EQGHNTFAYVPFSAGPKNCIGQKFAVLEMKVL 468
            .:.:..:..|.|...: .|...|:|||:|:.. :|......|:.|..||:.|:|.:.|.:|.|:|
 Worm   414 MVQVDTWSLHTDTKIWGDDAKEFKPERWLDPNCDQVFQKGGYISFGLGPRQCVGMRLAYMEEKML 478

  Fly   469 ISKVLRFY 476
            ::.:||.|
 Worm   479 LAHILRKY 486

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d20	NP_647723.2	CYP4	68..501	CDD:410721	114/460 (25%)
cyp-13A10	NP_496085.3	CYP3A-like	64..509	CDD:410678	115/465 (25%)