Protein Alignment Cyp4d20 and CYP4A11

DIOPT Version :10

• Sequence 1: NP_647723.2
• Gene: Cyp4d20 / 38311
• FlyBaseID: FBgn0035344
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: NP_000769.2
• Gene: CYP4A11 / 1579
• HGNCID: 2642
• Length: 519
• Species: Homo sapiens
• Alignment Length: 463
• Identity: 152/463 - (32%)
• Similarity: 240/463 - (51%)
• Gaps: 48/463 - (10%)

  Fly    62 EKFDKYGKTF----RFWILGESL-IYTKDLQYFETILSSTTLLEKGQLYEYLRPFLNDGLLVSTG 121
            ::..|:.:||    ..|:.|..: :...|..|.:.||..:.....|. |.:|.|::..|||:..|
Human    73 QRIQKWVETFPSACPHWLWGGKVRVQLYDPDYMKVILGRSDPKSHGS-YRFLAPWIGYGLLLLNG 136

  Fly   122 RKWHARRKIFTHAFHFKVLEHYVEIMDRHSSVMVDNLRKVADGKTAVDMLKYVSLAALDVITEAA 186
            :.|...|::.|.|||:.:|:.||.:|.....||:|...::....:.:::.::|||..||.|.:.|
Human   137 QTWFQHRRMLTPAFHYDILKPYVGLMADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKCA 201

  Fly   187 MGVQVNAQNDPDF-PYIKALKSV----------VYIQPDRMFRFSRRYNWLFPLAAPLLHRQLLS 240
            ...|.:.|.|.:. .||:|:..:          .:.|.|.::..:....|        .||.
Human   202 FSHQGSIQVDRNSQSYIQAISDLNNLVFSRVRNAFHQNDTIYSLTSAGRW--------THRA--- 255

  Fly   241 DIRVMHDFTDKVISERRETVRRAKADGTYRPLSLGDAE-IGSKSQMALLDILLQSSI-NNQPLSD 303
             .::.|..||:||..|:..:::.           |:.| |..|..:..|||||.:.: |...|||
Human   256 -CQLAHQHTDQVIQLRKAQLQKE-----------GELEKIKRKRHLDFLDILLLAKMENGSILSD 308

  Fly   304 ADIREEVDTFMFEGDDTTSSGVSHALYAIARHPEVQQRIFEELQRVLGPDASAPVTQAQLQDLKY 368
            .|:|.|||||||||.|||:||:|..|||:|.||:.|:|..||:..:||..||  :|...|..:.|
Human   309 KDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCREEIHSLLGDGAS--ITWNHLDQMPY 371

  Fly   369 LDCVIKETMRLYPPVPAIGRHAQKELEIGD-KTIPANTSIYLVLYYAHRDANYFPDPLSFRPERF 432
            ....|||.:|||||||.|||.....:...| :::|....:.|.:|..|.:...:|:|..|.|.||
Human   372 TTMCIKEALRLYPPVPGIGRELSTPVTFPDGRSLPKGIMVLLSIYGLHHNPKVWPNPEVFDPFRF 436

  Fly   433 LEDQEQGHNTFAYVPFSAGPKNCIGQKFAVLEMKVLISKVLRFYELLPLGEELK-PMLNFILRSA 496
            .....|  ::.|::|||.|.:||||::||:.|:||..:..|..:||||....:. |:...:|:|.
Human   437 APGSAQ--HSHAFLPFSGGSRNCIGKQFAMNELKVATALTLLRFELLPDPTRIPIPIARLVLKSK 499

  Fly   497 SGINVGLR 504
            :||::.||
Human   500 NGIHLRLR 507

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d20	NP_647723.2	CYP4	68..501	CDD:410721	149/452 (33%)
CYP4A11	NP_000769.2	CYP4B-like	74..505	CDD:410771	150/458 (33%)