Protein Alignment Cyp4d20 and Cyp51

DIOPT Version :10

• Sequence 1: NP_647723.2
• Gene: Cyp4d20 / 38311
• FlyBaseID: FBgn0035344
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: NP_064394.2
• Gene: Cyp51 / 13121
• MGIID: 106040
• Length: 503
• Species: Mus musculus
• Alignment Length: 471
• Identity: 115/471 - (24%)
• Similarity: 198/471 - (42%)
• Gaps: 99/471 - (21%)

  Fly    39 IPILGCGLQALHLGAENIIGWVGEKFDKYGKTFRFWILGESLIY--------------TKDLQYF 89
            ||.||   .|:..| ::.|.::...::|||..|.|.::|::..|              .:||...
Mouse    68 IPFLG---HAIAFG-KSPIEFLENAYEKYGPVFSFTMVGKTFTYLLGSDAAALLFNSKNEDLNAE 128

  Fly    90 ETILSSTT-LLEKGQLYEYLRP-FLNDGLLVSTGRKWHARRKIFTHAFHFKVLEHYVEIMDRHSS 152
            |.....|| :..||..|:.... ||....::.:|          .:..|||   .||.|:::.:.
Mouse   129 EVYGRLTTPVFGKGVAYDVPNAIFLEQKKIIKSG----------LNIAHFK---QYVPIIEKEAK 180

  Fly   153 VMVDNLRKVADGKTAVDMLKYVSLAALDVIT--EAAMGVQVNAQNDPDFPYIKALKSVVYIQPDR 215
            ....:..:  .|:..|    :.:|:.|.::|  ....|.::.:|       :....:.:|...|.
Mouse   181 EYFQSWGE--SGERNV----FEALSELIILTASHCLHGKEIRSQ-------LNEKVAQLYADLDG 232

  Fly   216 MFRFSRRYNWLFPLAAPL--------LHRQLLSDIRVMHDFTDKVISERR------ETVRRAKAD 266
            .|..:.   ||.|...||        .||::       .:...|.|.:||      |.:.:...|
Mouse   233 GFTHAA---WLLPAWLPLPSFRRRDRAHREI-------KNIFYKAIQKRRLSKEPAEDILQTLLD 287

  Fly   267 GTYRPLSLGDAEIGSKSQMALLDILLQSSINNQPLSDADIREEVDTFMFEGDDTTSSGVSHALYA 331
            .||:                          :.:||:|.:|...:...:..|..|:|:..:...:.
Mouse   288 STYK--------------------------DGRPLTDEEISGMLIGLLLAGQHTSSTTSAWMGFF 326

  Fly   332 IARHPEVQQRIFEELQRVLGPDASAPVTQAQLQDLKYLDCVIKETMRLYPPVPAIGRHAQKELEI 396
            :|:...:|::.:.|.:.|.|.|. .|:|..||:||..||..||||:||.||:..:.|.|:....:
Mouse   327 LAKDKPLQEKCYLEQKAVCGEDL-PPLTYDQLKDLNLLDRCIKETLRLRPPIMTMMRMAKTPQTV 390

  Fly   397 GDKTIPANTSIYLVLYYAHRDANYFPDPLSFRPERFLEDQEQGHNTFAYVPFSAGPKNCIGQKFA 461
            ...|||....:.:......|..:.:.:.|.|.|:|:|:|.......||||||.||...|:|:.||
Mouse   391 AGYTIPPGHQVCVSPTVNQRLKDSWAERLDFNPDRYLQDNPASGEKFAYVPFGAGRHRCVGENFA 455

  Fly   462 VLEMKVLISKVLRFYE 477
            .:::|.:.|.:||.||
Mouse   456 YVQIKTIWSTMLRLYE 471

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d20	NP_647723.2	CYP4	68..501	CDD:410721	106/442 (24%)
Cyp51	NP_064394.2	CYP51-like	88..499	CDD:410668	108/447 (24%)