Protein Alignment Cyp4d20 and cyp26c1

DIOPT Version :10

• Sequence 1: NP_647723.2
• Gene: Cyp4d20 / 38311
• FlyBaseID: FBgn0035344
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: XP_031761583.1
• Gene: cyp26c1 / 100489980
• XenbaseID: XB-GENE-1219115
• Length: 608
• Species: Xenopus tropicalis
• Alignment Length: 605
• Identity: 124/605 - (20%)
• Similarity: 204/605 - (33%)
• Gaps: 200/605 - (33%)

  Fly     6 ITGALILL-----------LTWDFGRKRQRVLAFEKSAIPGPISIPILGCGLQALHLGAENIIGW 59
            :|.||.|:           |.|...|.|...|...|    |.:..|..|   :.||        |
 Frog    16 LTSALSLVLLLAASHQLWSLRWHSTRDRGSSLPLPK----GSMGWPFFG---ETLH--------W 65

  Fly    60 V--GEKF-----DKYGKTFRFWILGESLIYTKDLQYFETILSSTTLLEKGQLYEYLRPFLNDGLL 117
            :  |..|     :|||..|:..:||:.:|.....:....||.....|...|..:..:..|....|
 Frog    66 LVQGSSFHSSRREKYGNIFKTHLLGKPVIRVTGAENIRKILLGEHHLVSTQWPQSTQIILGSNTL 130

  Fly   118 V-STGRKWHARRKIFTHAFHFKVLEHYVEIMDRHSSVMVDNLRKVADGKTAVDMLKYVSLAALDV 181
            . |.|.....:||:.:.......||.|:..:  |.:|..: :|....|...|.||.........:
 Frog   131 SNSIGELHRQKRKMMSKVLSSAALESYLPRI--HEAVRWE-VRSWCRGVGPVSMLSCAKALTFRI 192

  Fly   182 ITEAAMGVQVNAQNDPDFPYI-KALKSVVYIQPDRMFRFSRRYNWLFPLAAPLLHRQLLSDIR-- 243
            .....:|:.:   .|..|..: :..:.:|    :.:|        ..||..|      .|.:|
 Frog   193 AARILLGLSL---TDTQFQELTRTFEQLV----ENLF--------CLPLDIP------FSGLRKG 236

  Fly   244 -----VMHDFTDKVISERRETVRRAKADGTYRPLSLGDAEIGSKSQMALLDILLQSS------IN 297
                 .:|.:.::.|.|     :.:|.|    |.:..||          ||.|:.|:      ||
 Frog   237 MKARDTLHQYMEEAIKE-----KLSKRD----PDACEDA----------LDYLINSAKEGGKEIN 282

  Fly   298 NQPLSDADIREEVDTFMFEGDDTTSSGVSHALYAIARHPEVQQRIFEELQR-------------- 348
            .|.|.::.|.     .:|....||:|..:..:..:.:||....:|.:||..
 Frog   283 MQELKESAIE-----LIFAAFLTTASASTSLVLLLLKHPSAIHKIRQELASHGLSEHCEQCLPAT 342

  Fly   349 ------------------------VLGPDA----------------------------------- 354
                                    |:|.:.
 Frog   343 ENPNNNILQDNGHQCLTAGCQLPLVMGTEGQVKTLWEQTKQLLTDRTDQDPQNSLSSKNLVNGEN 407

  Fly   355 ---SAP---------------------------VTQAQLQDLKYLDCVIKETMRLYPPVPAIGRH 389
               .||                           ::..:|:.|.|||||:||.:||.|||....|.
 Frog   408 RIQEAPCSHDKSNCSPVPGKLQNSVFEGTCQQNISLEKLKSLHYLDCVVKEVLRLLPPVSGGYRT 472

  Fly   390 AQKELEIGDKTIPANTSIYLVLYYAHRDANYFPDPLSFRPERFLEDQEQGH-NTFAYVPFSAGPK 453
            |.:..|:....||...|:...:...|..|..:.:...|.||||..::::|. ..|.|:||..|.:
 Frog   473 ALQTFELDGYQIPKGWSVMYSIRDTHETAAVYQNAEMFDPERFSTERDEGKLGRFNYIPFGGGAR 537

  Fly   454 NCIGQKFAVLEMKVLISKVL 473
            :|||::.|.:.:|:|..:::
 Frog   538 SCIGKELAQIILKILAMELV 557

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d20	NP_647723.2	CYP4	68..501	CDD:410721	104/525 (20%)
cyp26c1	XP_031761583.1	cytochrome_P450	59..588	CDD:477761	112/558 (20%)