Protein Alignment Cyp4d20 and Cyp3a59

DIOPT Version :10

• Sequence 1: NP_647723.2
• Gene: Cyp4d20 / 38311
• FlyBaseID: FBgn0035344
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: NP_001098630.1
• Gene: Cyp3a59 / 100041449
• MGIID: 3769707
• Length: 503
• Species: Mus musculus
• Alignment Length: 513
• Identity: 137/513 - (26%)
• Similarity: 244/513 - (47%)
• Gaps: 75/513 - (14%)

  Fly     2 WLTLITGALILLL--TWDFGRKRQRVLAFEKSAIPGPISIPILGC------GLQALHLGAENIIG 58
            |:.|:|..:...:  |:..|       .|:|..||||..:|:.|.      |:
Mouse    12 WVLLVTSLVFFYIYGTYSHG-------LFKKLGIPGPKPLPLFGTIFNYFDGM------------ 57

  Fly    59 WVGEKFD-----KYGKTFRFWILGESLIYTKDLQYFETILSSTTLLEKGQLYEYL--RP------ 110
            |   |||     ||||.:.|::..:.::...|.:..:.:|..       :.|...  ||
Mouse    58 W---KFDEDCYKKYGKIWGFYVGPKPILAIMDPEIIKIVLVK-------ECYSVFTNRPTLGPVG 112

  Fly   111 FLNDGLLVSTGRKWHARRKIFTHAFHFKVLEHYVEIMDRHSSVMVDNLRKVADGKTAVDMLKYVS 175
            ||...:.:|...:|...|.:.:..|....|:....||.::..::|.|||:..:....::|.....
Mouse   113 FLKKSITISEDEEWKRLRTLLSPTFTSGKLKEMFPIMRQYGDILVRNLRREEEKGEPINMKDIFG 177

  Fly   176 LAALDVITEAAMGVQVNAQNDPDFPYIKALKSVVYIQPDRMFRFSRRYNWLFPLAAPLLHRQLLS 240
            ..::||||..:.||.:::.|:|..|:::..|.::..:....|..|   ..|||...|:.....||
Mouse   178 AYSMDVITGTSFGVNIDSLNNPQNPFVQKTKKILKFKIFDPFLLS---TILFPFLTPIYEMLNLS 239

  Fly   241 -----DIRVMHDFTDKVISERRETVRRAKADGTYRPLSLGDAEIGSKSQMALLDILLQSSINNQP 300
                 .:.....|..::..||..:.::.:.|.....::..::: |.:||.|
Mouse   240 IFPRDSMNFFKKFVKRMKKERLASKQKNRVDFLQLMMNTQNSK-GQESQKA-------------- 289

  Fly   301 LSDADIREEVDTFMFEGDDTTSSGVSHALYAIARHPEVQQRIFEELQRVLGPDASAPVTQAQLQD 365
            |||.::..:...|:|.|.|.||:.:|..:|.:|.||:||:::.:|:.|.| |: .||||...|.|
Mouse   290 LSDLEMAAQAVIFIFGGYDATSTSISLIMYELATHPDVQKKLQDEIDRTL-PN-KAPVTYDALMD 352

  Fly   366 LKYLDCVIKETMRLYPPVPAIGRHAQKELEIGDKTIPANTSIYLVLYYAHRDANYFPDPLSFRPE 430
            ::|||.|:.|::||||....:.|.::|::||....||..|.:.:.:|..||:..|:|:|..|.|.
Mouse   353 MEYLDMVVNESLRLYPTAIRLERVSKKDVEINGVFIPKGTVVMIPIYPLHRNPEYWPEPQEFCPG 417

  Fly   431 RFLEDQEQGHNTFAYVPFSAGPKNCIGQKFAVLEMKVLISKVLRFYELLPLGEELKPM 488
            ||.::.|...:.:.|:||..||:||:..:||::.||:.:..||:.:.:.|..|...|:
Mouse   418 RFSKENEGNIDPYIYMPFGNGPRNCLDMRFALISMKLAVIGVLQNFTVQPCEETQIPL 475

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d20	NP_647723.2	CYP4	68..501	CDD:410721	117/434 (27%)
Cyp3a59	NP_001098630.1	CYP3A	67..492	CDD:410743	119/436 (27%)