| Sequence 1: | NP_001286919.1 | Gene: | Svil / 38306 | FlyBaseID: | FBgn0266696 | Length: | 4526 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_071292.1 | Gene: | Flii / 14248 | MGIID: | 1342286 | Length: | 1271 | Species: | Mus musculus |
| Alignment Length: | 1433 | Identity: | 280/1433 - (19%) |
|---|---|---|---|
| Similarity: | 493/1433 - (34%) | Gaps: | 425/1433 - (29%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 3202 ENSTPKHDDAVSLVRNLSTLGQPRSLARDDAAGNCASASEGESSGGREIEAIIKNSAVARRRRQQ 3266
Fly 3267 QQQSQQQNQPDGNLVAKSKSHSGI-SAP----IGLG------------PQLPPLPLGGGFVKLRH 3314
Fly 3315 VAKEEDTSSSSNT---SSAKESP-----DKKDLRQEQAEASGDSSHPTALPQFLQGVQRSSTEVM 3371
Fly 3372 G--------------PDQRSLVISKTGSIAERLAALHKSGEDDWKKRISKRDEVDDVHRENF--- 3419
Fly 3420 VNESLSL----------------AHSLSDKPLPPS-----------------PLIPTSLEGGKVS 3451
Fly 3452 DRLSKLKCNSENWKQRIEQTDAKKFTVAGRLQKKAQSPVELQFERSANDAAKKCPMLEVRSANQP 3516
Fly 3517 QLGLAKSPSMMVTSSTSTNSTSKSAL-RSLSVNPEEEGPTSLSRSNSSSSESDGERKSPQNAKQN 3580
Fly 3581 KELANNKSAAAPTNVGAR----IQVPRLDDKETF---------------ENF--------FSSKP 3618
Fly 3619 KKEENVQLEISAFDDIKPT-----------ERLVSKRHVQGPKGRRAARNPLKSLAAREDISSEY 3672
Fly 3673 TEMRSGIAERELRRLKL----ESYGHNANLAAEAIAGLASVEDFKSVALRSSSIPLQQMWLPHKP 3733
Fly 3734 VMLLHVKGRTHVQTRLVEPV---HTSLNRGDCFILVAGSQLFRYVGSFANVIEISRSKKICAAIV 3795
Fly 3796 ENKDLGCTATQEVILTDGKYLKERQWRQFWQLLGKKEDDQSDIAECGHADED------------- 3847
Fly 3848 --DVFESSLIETNKIYEYQDEALIPLEKFWGCIPKVD----------MLDTRKVLVFDFGSELYV 3900
Fly 3901 WNGKNAPSDAKRAAMRLAQEHFGAENSADYADCYLNPLNYVAIVGRRENTKYAKRCAQRPEWCVL 3965
Fly 3966 GKITQNMETVLFKEKFSDWPEIEREDLEKDYLSN--GVHMVRALNGTALHKGE------------ 4016
Fly 4017 --PYQEPNLVLEQANLGRGNFYYDTDTMRHFDVITKSTDKWQIHEFNFDAANNRDDYGHFYSAES 4079
Fly 4080 YIV---RWI---YQISVTVRELSGKVSNRSTVGRD--------------RCVYFTWQGQDSSANE 4124
Fly 4125 KGAAALLTVELDKE-------KGAQMRVSQGDECTAFVRLF-RQMWQHRGRKEQCLERHSEWRLY 4181
Fly 4182 QLQGNVSEE-TIIKEVVCQSSHLRSRSSMLL-----IHGSQGNVIVWHGSKSAPHTRNVAVGVAQ 4240
Fly 4241 DLIKTVPKDLFSAETANLTEVEEGSDDDQ-CKKALGLKDERNEYGSLLKSTKSFDYQIRIFNFSS 4304
Fly 4305 TQGVFKALELSDPLRCQDLHSPYPFSQSQLYNARQPTIFLLDDGDELWLWMGWWPLE-DVKINTD 4368
Fly 4369 ERSSPTNENRAGVNRWISERRAALETAVDYWRAKHGENENEPFHGIKGQVVWAGLEPLAFKALFP 4433
Fly 4434 DWT 4436 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Svil | NP_001286919.1 | gelsolin_S2_like | 3733..3825 | CDD:200445 | 17/94 (18%) |
| gelsolin_like | 3859..3965 | CDD:200436 | 22/115 (19%) | ||
| ADF_gelsolin | <4069..4158 | CDD:301701 | 24/115 (21%) | ||
| gelsolin_S5_like | 4176..4279 | CDD:200444 | 26/109 (24%) | ||
| ADF_gelsolin | 4328..4435 | CDD:301701 | 22/107 (21%) | ||
| VHP | 4492..4526 | CDD:280388 | |||
| Flii | NP_071292.1 | Interaction with LRRFIP1 and LRRFIP2. /evidence=ECO:0000250 | 1..427 | 80/417 (19%) | |
| LRR_RI | <2..137 | CDD:238064 | 15/85 (18%) | ||
| leucine-rich repeat | 10..34 | CDD:275380 | |||
| LRR_8 | 33..91 | CDD:290566 | 9/39 (23%) | ||
| leucine-rich repeat | 35..57 | CDD:275380 | |||
| leucine-rich repeat | 58..80 | CDD:275380 | 6/20 (30%) | ||
| LRR_RI | 89..352 | CDD:238064 | 56/301 (19%) | ||
| leucine-rich repeat | 106..128 | CDD:275380 | 2/21 (10%) | ||
| leucine-rich repeat | 129..152 | CDD:275380 | 8/22 (36%) | ||
| LRR_8 | 131..186 | CDD:290566 | 13/62 (21%) | ||
| leucine-rich repeat | 153..175 | CDD:275380 | 4/29 (14%) | ||
| leucine-rich repeat | 176..199 | CDD:275380 | 2/22 (9%) | ||
| leucine-rich repeat | 200..224 | CDD:275380 | 8/30 (27%) | ||
| LRR_8 | 223..281 | CDD:290566 | 14/75 (19%) | ||
| leucine-rich repeat | 225..247 | CDD:275380 | 1/21 (5%) | ||
| leucine-rich repeat | 248..270 | CDD:275380 | 8/39 (21%) | ||
| leucine-rich repeat | 271..318 | CDD:275380 | 7/46 (15%) | ||
| leucine-rich repeat | 319..341 | CDD:275380 | 6/27 (22%) | ||
| gelsolin_S1_like | 492..604 | CDD:200446 | 17/127 (13%) | ||
| Interaction with ACTL6A. /evidence=ECO:0000250 | 495..827 | 72/424 (17%) | |||
| gelsolin_like | 619..703 | CDD:200436 | 17/93 (18%) | ||
| gelsolin_S3_like | 723..837 | CDD:200448 | 30/157 (19%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 951..977 | 4/25 (16%) | |||
| gelsolin_like | <981..1036 | CDD:200436 | 13/57 (23%) | ||
| gelsolin_S5_like | 1055..1154 | CDD:200444 | 26/107 (24%) | ||
| Gelsolin-like 4 | 1070..1117 | 13/46 (28%) | |||
| gelsolin_S6_like | 1165..1264 | CDD:200447 | 31/147 (21%) | ||
| Gelsolin-like 5 | 1178..1220 | 15/55 (27%) | |||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 0 | 0.000 | Not matched by this tool. | |||
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 1 | 1.010 | - | - | D1376537at2759 | |
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| 2 | 1.920 | |||||