Protein Alignment CG9004 and AgaP_AGAP011285

DIOPT Version :9

• Sequence 1: NP_647717.1
• Gene: CG9004 / 38303
• FlyBaseID: FBgn0035336
• Length: 854
• Species: Drosophila melanogaster
• Sequence 2: XP_309361.4
• Gene: AgaP_AGAP011285 / 1270646
• VectorBaseID: AGAP011285
• Length: 988
• Species: Anopheles gambiae
• Alignment Length: 1004
• Identity: 375/1004 - (37%)
• Similarity: 531/1004 - (52%)
• Gaps: 199/1004 - (19%)

  Fly     6 KKEAKAKPL-TRKEQRKQKSEFKKQNKRLYFAGKTNGTQRVAAAAEALAAQSQLGKNKKKKRSKK 69
            :|.:||..: |||:.||:|.:.||.| |..:..::...::...|.:        |:::|:...|
Mosquito    16 RKSSKAPAVKTRKDLRKEKRQQKKLN-RFNYHNRSRKERQGQGAGD--------GRHQKQHGGK- 70

  Fly    70 PKIINPDEIPKEQLLSGEIDS---DDDESIDS-DFSDAEVDALLPAREKMEVYEPLGKKVKKTTG 130
                    ...:|...|:.:|   ||||.|.| ||||.|...  ....|...::|:.|......
Mosquito    71 --------FAHDQQSDGDDESEVFDDDEEIPSDDFSDEEDSG--KGMAKGSKHQPVSKPYTSQL- 124

  Fly   131 GAIQRQDEEAVRRKELRQQKELESKSKKQRIKQLRIENEEDDREINKLEKKLKLNKSKDKNRLVR 195
                    |..|.||:.:.:..|...|..|||||...||||||.|.|.||.||:|:.::|.. :.
Mosquito   125 --------EVEREKEIMELRRYEEGLKSNRIKQLEAANEEDDRVIEKYEKLLKINRRRNKEG-IP 180

  Fly   196 KMFNDGLDYLLD----------------------------------------------------- 207
            |.|||||||.|:
Mosquito   181 KSFNDGLDYALELCTDESIRKMYEAAKEAAELEENSGDEFVEDLKQAVGGKLNVEPKEDSGEPSK 245

  Fly   208 ---------------------------FVLDD--------------------------------- 212
                                       |.|||
Mosquito   246 RTKKRKEKLSPKERKRVEKLKKIEEKYFGLDDMDDDLGEYDSEMEQEEEVADENGGESDYSENDE 310

  Fly   213 ------------------EEEKR--------KWEEKQ-----ERKKKL----KEQQEKEEAGMWS 242
                              ||||.        |.:|||     |.|||.    |...:.||...:.
Mosquito   311 LYDSDEEEDDELESDEEREEEKNGKRVKFAPKEKEKQSKNGKETKKKATGKQKASSDSEEEPEYD 375

  Fly   243 DEEEDKEDRDEPMDNFSEDDSGSEGEDDDEDLTGEEEQSEEDSEQEENAPKIKEDIYGRKRDAEG 307
            |||:|.:|.|:.:|:..:|:|||:...|.||  |.:..:::|.       ...|||||||||..|
Mosquito   376 DEEQDFDDEDDGLDDLFDDESGSDDPSDGED--GSKSSTKKDD-------GTWEDIYGRKRDKAG 431

  Fly   308 NILPDPVELEASAAGQKYIPPHQRALMAASA-----GSSEKQAEILARLLKQCKGLLNRLSEANL 367
            ||:.:. ...|.|.|.||:|||.||.:.|.|     .:..||.|.|.||.:..||.:|||:|:|:
Mosquito   432 NIIKED-NSSAGATGGKYVPPHLRAKLEAEAAAKGNATDPKQQERLQRLQRTLKGQINRLAESNV 495

  Fly   368 HKIAAGIEELYMKNSRYNMNETLTKLIQEALLGYTRTNERMVQEHMVLLAYLHAQVGSEIGAHFL 432
            |:|:..::.|||:|:|::||.|||.||.||.:..|.|.||||.|||:|:|.|||.||.|:|:.||
Mosquito   496 HRISITLDNLYMQNARHDMNSTLTALILEATVVPTLTPERMVLEHMLLVAILHANVGGEVGSQFL 560

  Fly   433 QTFVELFDGYVKNIATLEVEDKQLNNLVLVLCYMYLFKIYELNLLMELIGKLSDQLCEKSVECLL 497
            :|.|..|...:..|.|...|.|||:|.|.::|::|.|.|.:..::.|::.||.....||:|||:|
Mosquito   561 ETIVGRFLELLGEIETTPNEAKQLDNCVQLMCHLYTFDIVKCKIVHEVMQKLIQCFNEKAVECIL 625

  Fly   498 LIFQSIGFRLRKDDPLAFKTMMQKVQSQIASAPLELKENPRLRFMVDILNAVKNNNMQKLPQYDP 562
            |:.:::||.||||||||.|.::..:|.:.|:||.:||.:||:::|::||.|||||||.|:|||||
Mosquito   626 LVLRTVGFILRKDDPLALKELIIAIQKKAANAPDKLKNDPRVKYMLEILLAVKNNNMSKIPQYDP 690

  Fly   563 ELAENLRKRLKAMLKNDRYVVTLNITLEDLLRADKVGKWWIVGSAWTGNLDEMGSAKQKQDKNSS 627
            .|.|:.||.||.|:...:||.:|||.:||:::..:.||||:|||||.|..|...:...|....|:
Mosquito   691 TLVEHFRKLLKGMINTGKYVSSLNIGIEDIVKIPERGKWWLVGSAWLGAKDAGPNTGGKPGTTST 755

  Fly   628 KSANGGFADQLLELARKQQMNTAERRNIFCIIMSAADYVDAFEKILHLSLKDQRAVAYVIIHCAL 692
            .:....:::|||||||:|:|||.:|||.|||||||.||:|||||:|.|::||.|.:..|||||||
Mosquito   756 STGEAQYSEQLLELARQQRMNTDDRRNAFCIIMSAEDYLDAFEKLLRLAIKDLRILVSVIIHCAL 820

  Fly   693 NEKRANPYYAHLALKFCQFNRKYQLAFQFASWDRINDIEKLSKPQIRNLASFLQQVILAAGLQLS 757
            .||..||||:.||.|||.::|:||||.|:|.|||:.:|..|.:.|:||||.|:..:|...||.||
Mosquito   821 AEKDYNPYYSVLAQKFCDYDRRYQLAIQYALWDRLKEIHSLQQQQVRNLARFITHLIGEGGLALS 885

  Fly   758 VLKVVDFMQLDKLSFYFMKEVMVRLLLANDEREIYQTFERVAKNTKLQQFKQSVRLFLQHFLLQ- 821
            .|||||..::||::...|:::|:.|||..||.:..|.|.|::.:.||:.||..:|||:.|||.:
Mosquito   886 CLKVVDLAEIDKVNLRLMRQIMLGLLLMEDENKCLQVFSRISASFKLKAFKDGIRLFMHHFLARG 950

  Fly   822 EEQLDKLKLKDEDRQLLQQRVDHIDKLLA 850
            ....:...|.:|..||||:|:...|:|||
Mosquito   951 SSSANSSSLPEEQVQLLQERIKQADELLA 979

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9004	NP_647717.1	MIF4G	352..553	CDD:280935	94/200 (47%)
		MA3	652..755	CDD:280933	60/102 (59%)
AgaP_AGAP011285	XP_309361.4	MIF4G	480..681	CDD:280935	94/200 (47%)
		MA3	780..882	CDD:280933	59/101 (58%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	191	1.000	Domainoid score	I6754
eggNOG	1	0.900	-	-		E1_KOG2141
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H39776
Inparanoid	1	1.050	584	1.000	Inparanoid score	I2500
OMA	1	1.010	-	-		QHG53878
OrthoDB	1	1.010	-	-		D189414at33208
OrthoFinder	1	1.000	-	-		FOG0004175
OrthoInspector	1	1.000	-	-		otm50695
Panther	1	1.100	-	-	LDO	PTHR18034
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2926
TreeFam	1	0.960	-	-
	13	12.940