Protein Alignment MsR1 and srw-101

DIOPT Version :10

• Sequence 1: NP_001261324.1
• Gene: MsR1 / 38298
• FlyBaseID: FBgn0035331
• Length: 556
• Species: Drosophila melanogaster
• Sequence 2: NP_001024317.1
• Gene: srw-101 / 3565911
• WormBaseID: WBGene00005848
• Length: 359
• Species: Caenorhabditis elegans
• Alignment Length: 420
• Identity: 87/420 - (20%)
• Similarity: 166/420 - (39%)
• Gaps: 111/420 - (26%)

  Fly    30 YVSLVVCILGTIANTLNIIVLTRREMRSPT-NAILTGLAVADLAVMLE--YIPYTIHDY-----I 86
            :|:.::.:.....|..::|:|||:.||:.: |..:.|:|:.||...|.  |..:::.|:     |
 Worm    27 FVNFILSVFSIFINIFHVIILTRKSMRATSINVFMIGIAICDLCTTLTTVYRYFSLVDFEYPECI 91

  Fly    87 LTDSLPREEKLSYSWACFIKFHSIFAQVLHTISIWLTVTLAVWRYIAVGYPQKNRVWCGMRTTII 151
            .:|||.:....:.||:  :::|      ....|.||.:.:|                 |:|..|:
 Worm    92 TSDSLVKAYADAMSWS--VQYH------FKRCSSWLGILMA-----------------GVRILIM 131

  Fly   152 -TITTAYVVCVLVVSPSLYLITAITEYVDQLDMNGKVINSIPMTQYVIDYRNELLSARTAALNAT 215
             .|:.|             ..:.|.:.:..:.:...|.....:...|..|..:::..||..|  :
 Worm   132 RKISNA-------------KFSKIMKPIFGISLMAIVFGISGILTTVWQYECQVIENRTYPL--S 181

  Fly   216 PTSAPLNETVWLNASTLLTSTTTAAPPTPSPVVRNVTVYRLYHSDLALHNASLQNATFLIYSVVI 280
            |..|...:...:...:|:.        .|...|.:|.:.|.|               |:..|::.
 Worm   182 PNCAEHQDIHGVFRFSLIL--------RPVSTVADVVILRSY---------------FISDSIIS 223

  Fly   281 KLIPCIALTILSVRLILALLEAKRRRKKLTSKPATPGASNGTKSPANGKAADRPRKNSKTLEKEK 345
            .|||.|:..:|:|.||       |..:||.                  |:..|..:...|.|.|:
 Worm   224 SLIPGISFPLLAVVLI-------REIRKLE------------------KSRTRAIRTLSTAENEE 263

  Fly   346 QTDRTTRMLLAVLLLFLITEFPQGIMGLLNAVL--GDVFYLQCYLR-LSDLM---DILALINSSI 404
            :...:|:::..:.:...::|.|.|::.:.....  ||:     .:| |:||:   .|||...|.:
 Worm   264 KYGLSTKLIGLMTVAAFLSETPLGLISIFKQFFTKGDI-----NIRLLTDLVIYFTILATFVSIL 323

  Fly   405 NFILYCSMSKQFRTTFTLLFRPKFLDKWLP 434
            :.:|...||.::..|...:|.   :.|.||
 Worm   324 HPVLCLLMSSKYCETLRKMFG---ISKTLP 350

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MsR1	NP_001261324.1	7tmA_FMRFamide_R-like	28..420	CDD:410630	82/404 (20%)
		TM helix 1	28..53	CDD:410630	5/22 (23%)
		TM helix 2	59..84	CDD:410630	7/27 (26%)
		TM helix 3	105..135	CDD:410630	5/29 (17%)
		TM helix 4	147..167	CDD:410630	4/20 (20%)
		TM helix 5	269..294	CDD:410630	7/24 (29%)
		TM helix 6	345..375	CDD:410630	4/29 (14%)
		TM helix 7	388..413	CDD:410630	9/28 (32%)
srw-101	NP_001024317.1	7TM_GPCR_Srw	27..345	CDD:402097	84/413 (20%)
		TM helix 1	30..49	CDD:410628	3/18 (17%)
		TM helix 2	58..80	CDD:410628	7/21 (33%)
		TM helix 3	103..125	CDD:410628	7/46 (15%)
		TM helix 4	150..166	CDD:410628	1/15 (7%)
		TM helix 5	213..236	CDD:410628	9/37 (24%)
		TM helix 6	269..291	CDD:410628	4/21 (19%)
		TM helix 7	307..332	CDD:410628	7/24 (29%)