Protein Alignment MsR1 and srw-102

DIOPT Version :10

• Sequence 1: NP_001261324.1
• Gene: MsR1 / 38298
• FlyBaseID: FBgn0035331
• Length: 556
• Species: Drosophila melanogaster
• Sequence 2: NP_001024316.1
• Gene: srw-102 / 3565707
• WormBaseID: WBGene00005849
• Length: 366
• Species: Caenorhabditis elegans
• Alignment Length: 434
• Identity: 92/434 - (21%)
• Similarity: 168/434 - (38%)
• Gaps: 131/434 - (30%)

  Fly    17 MDNFHTSYKNMHGY---VSLVVCILGTIANTLNIIVLTRREMR-SPTNAILTGLAVADLAVMLEY 77
            :.|......|:..|   .:|.:.::..|.|..:|:||:.:.|| |.||.||.||:::||.:.:.
 Worm    10 LQNVENVVNNIGLYFQRANLFLSLMSIILNVFHILVLSNKSMRTSSTNVILIGLSISDLGIAMS- 73

  Fly    78 IPYTIH-----------DYILTDSLPREEKLSYSWACFIKFHSIFAQVLHTISIWLTVTLAVWRY 131
               |::           :.|...||.:......:|:..|.|        ...|.:|.|.:|..||
 Worm    74 ---TMYKQMFMVDPQNSECITATSLSKVYMDITAWSVLIYF--------RRCSSFLGVLMASVRY 127

  Fly   132 IAVGYPQKNRVWCGMRTTIITITTAYVVCVLVVSPSLYLITAITEYVDQLDMNGKVINSIPMTQY 196
            :.:..|..:|.....:.::....|..|.|:
 Worm   128 VIMKKPTVSRYSNWSKPSVGWTLTGSVFCI----------------------------------- 157

  Fly   197 VIDYRNELLSARTAALNATPTSAPLNETVWLNASTLLTSTTTAAPPTPSPVVRNVTVYRLYHSDL 261
                 :.||                  |::..|..::.:..||..|......:|:.....|...|
 Worm   158 -----SGLL------------------TIFYQARWIVVANQTAPLPITCAQFQNLNSKPPYSVIL 199

  Fly   262 ALH----NASLQNATFLIYSVVI-KLIPCIALTILSVRLILALLEAKRRRKKLTSKPATPGASNG 321
            | |    |.::.:.:::|..|:| :.|||:|..||::.|:..|...|              .:|.
 Worm   200 A-HIFSANDAIIHRSYMIMDVLISRFIPCVAFIILTIALLRILQSIK--------------ITNL 249

  Fly   322 TKSPANGKAADRPRKNSKTLEKEKQTDRTTRMLLAVLLLFLITEFPQGIMGLLNAVLGDVFY--- 383
            |:           ||:|  :..:::.|.:|::::.:...|::.|.|.|::     .:|.|.:
 Worm   250 TR-----------RKSS--VHHDEKRDLSTKLIVVMTFTFVLIETPLGMI-----YMGRVIFDKN 296

  Fly   384 LQCYLRLSDLMDILALINSSINFIL---YC-SMSKQFRTTFTLL 423
            |...|..:||. :..|:..:||.||   :| .||.|:|.|..|:
 Worm   297 LMITLLSTDLA-VYFLMLVTINSILHPTFCILMSSQYRNTIRLM 339

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MsR1	NP_001261324.1	7tmA_FMRFamide_R-like	28..420	CDD:410630	88/418 (21%)
		TM helix 1	28..53	CDD:410630	7/27 (26%)
		TM helix 2	59..84	CDD:410630	9/35 (26%)
		TM helix 3	105..135	CDD:410630	8/29 (28%)
		TM helix 4	147..167	CDD:410630	3/19 (16%)
		TM helix 5	269..294	CDD:410630	9/25 (36%)
		TM helix 6	345..375	CDD:410630	6/29 (21%)
		TM helix 7	388..413	CDD:410630	9/28 (32%)
srw-102	NP_001024316.1	7TM_GPCR_Srw	27..341	CDD:402097	89/417 (21%)
		TM helix 1	29..48	CDD:410628	6/18 (33%)
		TM helix 2	57..79	CDD:410628	8/25 (32%)
		TM helix 3	102..124	CDD:410628	6/29 (21%)
		TM helix 4	149..165	CDD:410628	6/73 (8%)
		TM helix 5	212..235	CDD:410628	9/22 (41%)
		TM helix 6	266..286	CDD:410628	5/19 (26%)
		TM helix 7	301..329	CDD:410628	9/28 (32%)