Protein Alignment MsR1 and srw-123

DIOPT Version :10

• Sequence 1: NP_001261324.1
• Gene: MsR1 / 38298
• FlyBaseID: FBgn0035331
• Length: 556
• Species: Drosophila melanogaster
• Sequence 2: NP_001023706.1
• Gene: srw-123 / 3565663
• WormBaseID: WBGene00005870
• Length: 365
• Species: Caenorhabditis elegans
• Alignment Length: 439
• Identity: 83/439 - (18%)
• Similarity: 149/439 - (33%)
• Gaps: 177/439 - (40%)

  Fly    35 VCILGTIANTLNIIVLTRREMR-SPTNAILTGLAVADL---------------AVMLEYIPYTIH 83
            :.|...:.|.::..:|||:.|| |..|.::..:|..|:               .:..|.:....:
 Worm    45 ISISSILINLVHFFILTRKPMRTSSINILMAAVAFFDIFTSLLPIEVLFERYKDIFFECLSLDTY 109

  Fly    84 DYILTDSLPREEKLSYSWACFIKFHSIFAQVLHTISIWLTVTLAVWR-----------YIAVGYP 137
            ..:||.:|....| .||..|               |.||...:|..|           |.|:|.|
 Worm   110 GLVLTKALLTVVK-DYSRRC---------------STWLIFFIAFIRTLIIQNPLSSKYEALGKP 158

  Fly   138 QKNRVWCGMRTTIITITTAYVVCVLVVSPSLYLITAITEYVDQLDMNGKVINSIPMTQYVIDYRN 202
                     :.:||.||.   :||:.:..|::.... .::|:.:..:    :..|.|.|:::..:
 Worm   159 ---------KASIIVITG---ICVVTLPISMFKFLE-NQFVESMPRD----SCAPNTTYIVNVLS 206

  Fly   203 ELLSARTAALNATPTSAPLNETVWLNASTLLTSTTTAAPPTPSPVVRNVTVYRLYHSDLALHNAS 267
            ||.                                          ::|..:...|.
 Worm   207 ELF------------------------------------------MKNDGIVMKYF--------- 220

  Fly   268 LQNATFLIYSVVIKLIPCIALTILSVRLILALLEAKRRRKKLTSKPATPGASNGTKSPANGKAAD 332
                 :|..|.:..:||||.|.|:::.|:..|.:..::|.|::|      .||...|  .||:.
 Worm   221 -----YLFNSSISDIIPCILLLIVTILLVWNLFKTSKKRTKISS------VSNNRNS--RGKSG- 271

  Fly   333 RPRKNSKTLEKEKQTDRTTRMLLAVLLLFLITEFPQGIM--------------GLLNAVLGDVFY 383
                                ::|.|.::|.:.|.|.|:.              .:||. .|.:|
 Worm   272 --------------------LVLCVAIMFFVVECPYGLSVGSAWIFIHAPGAHNMLNQ-FGAIF- 314

  Fly   384 LQCYLRLSDLMDILALINSSINFILYCSMSKQFRTTFTLLF-----RPK 427
                       .:|..:|:..:.|:...||.|:|:|...:|     |||
 Worm   315 -----------SMLITLNTCTHLIVCLFMSSQYRSTTIQVFSCGRIRPK 352

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MsR1	NP_001261324.1	7tmA_FMRFamide_R-like	28..420	CDD:410630	78/425 (18%)
		TM helix 1	28..53	CDD:410630	4/17 (24%)
		TM helix 2	59..84	CDD:410630	4/39 (10%)
		TM helix 3	105..135	CDD:410630	7/40 (18%)
		TM helix 4	147..167	CDD:410630	6/19 (32%)
		TM helix 5	269..294	CDD:410630	8/24 (33%)
		TM helix 6	345..375	CDD:410630	6/43 (14%)
		TM helix 7	388..413	CDD:410630	3/24 (13%)
srw-123	NP_001023706.1	7TM_GPCR_Srw	45..347	CDD:402097	80/432 (19%)
		TM helix 2	70..95	CDD:410630	3/24 (13%)
		TM helix 3	115..145	CDD:410630	10/45 (22%)
		TM helix 4	159..179	CDD:410630	7/22 (32%)
		TM helix 5	217..242	CDD:410630	9/38 (24%)
		TM helix 6	269..294	CDD:410630	7/45 (16%)
		TM helix 7	308..333	CDD:410630	6/37 (16%)