Protein Alignment MsR1 and srw-89

DIOPT Version :10

• Sequence 1: NP_001261324.1
• Gene: MsR1 / 38298
• FlyBaseID: FBgn0035331
• Length: 556
• Species: Drosophila melanogaster
• Sequence 2: NP_001024046.1
• Gene: srw-89 / 3564804
• WormBaseID: WBGene00005836
• Length: 361
• Species: Caenorhabditis elegans
• Alignment Length: 399
• Identity: 95/399 - (23%)
• Similarity: 146/399 - (36%)
• Gaps: 105/399 - (26%)

  Fly    31 VSLVVCILGTIANTLNIIVLTRREMR-SPTNAILTGLAVADLAVMLEYIPYTIHDYILTDSLPRE 94
            :..::..:|.:.|.|:|.:|||:.|. |..|:|:.|:|:.|...|:    ..:.:.||..||.:|
 Worm    32 IEFLMAKIGAVLNILHIFILTRKSMMISSVNSIMIGIAICDCICMI----IIVKNGILVRSLVQE 92

  Fly    95 --EKLSYSWACFIKFHSIFAQVLHTISIWLTVTLAVWRYIAVGYPQKNRVWC-----GMRTTIIT 152
              ..||...|.|..|.:.....|...|.||.:.:||.||..:......|...     |::.:||.
 Worm    93 CAPPLSQFEAQFDFFLTAVHNALRRCSAWLGMLVAVVRYFVIRNVTNIRAQVSIPKYGVKVSIIA 157

  Fly   153 ITTAYVVCVLVVSPSLYLITAITEYVDQLDMNGKVINSIPMTQYVIDYRNELLSARTAALNATPT 217
            ..|:.|..:.     .|.      :||.|::
 Worm   158 FFTSCVASIF-----FYF------HVDILEV---------------------------------- 177

  Fly   218 SAPLNETVWLNASTLLTSTTTAAPPTPSPVVRNVTVYRLYHSDLALHNASLQNATFLIYSVVIKL 282
                  ..|...|.....|...|.|....|...:..:         :||........:..|..||
 Worm   178 ------ATWTPKSDCEDFTDMTARPVHGQVSNEIFEW---------NNALFAKLRLYMECVFSKL 227

  Fly   283 IPCIALTILSVRLILALLEAKRRRKKLTSKPATPGASNGTKSPANGKAADRPRKNSKTLEKEKQT 347
            |.|.||.|||..||   .|.|                         |:|:...|:.|...|
 Worm   228 ITCFALPILSGLLI---TEMK-------------------------KSAEVSIKSFKKSRK---- 260

  Fly   348 DRTTRMLLAVLLLFLITEFPQGIMGLLNAV-LGDVFYLQCYLRLSDLMDILALINSSINFILYCS 411
            |.||.:.:.:.:.:.::|||.||:....|| .|::.||.....:......|..||:||:.::..|
 Worm   261 DLTTVITICIAISYFVSEFPLGIIYFYKAVWRGNLTYLNLAENVKLFCHSLFTINASIHCLICFS 325

  Fly   412 MSKQFRTTF 420
            ||.|:|.||
 Worm   326 MSHQYRKTF 334

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MsR1	NP_001261324.1	7tmA_FMRFamide_R-like	28..420	CDD:410630	93/397 (23%)
		TM helix 1	28..53	CDD:410630	6/21 (29%)
		TM helix 2	59..84	CDD:410630	6/24 (25%)
		TM helix 3	105..135	CDD:410630	9/29 (31%)
		TM helix 4	147..167	CDD:410630	4/19 (21%)
		TM helix 5	269..294	CDD:410630	10/24 (42%)
		TM helix 6	345..375	CDD:410630	8/29 (28%)
		TM helix 7	388..413	CDD:410630	6/24 (25%)
srw-89	NP_001024046.1	7TM_GPCR_Srw	32..339	CDD:402097	95/399 (24%)
		TM helix 2	62..85	CDD:410628	6/26 (23%)
		TM helix 3	106..128	CDD:410628	5/21 (24%)
		TM helix 4	152..168	CDD:410628	4/20 (20%)
		TM helix 5	215..238	CDD:410628	9/22 (41%)
		TM helix 6	264..286	CDD:410628	6/21 (29%)
		TM helix 7	302..327	CDD:410628	6/24 (25%)