DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment MsR1 and Proc-R

DIOPT Version :9

Sequence 1:	NP_001261324.1	Gene:	MsR1 / 38298	FlyBaseID:	FBgn0035331	Length:	556	Species:	Drosophila melanogaster
Sequence 2:	NP_001014723.1	Gene:	Proc-R / 31408	FlyBaseID:	FBgn0029723	Length:	545	Species:	Drosophila melanogaster

Alignment Length:	563	Identity:	119/563 - (21%)
Similarity:	206/563 - (36%)	Gaps:	167/563 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 LVVC--ILGTIANTLNIIVLTRREMRSPTNAILTGLAVADLAVMLEYIPYTIHDYILTDSLPREE 95
            ||.|  ::|.:.|:::|.||||:.||..||..||.||:.|:|       |.....||  ||...:
  Fly    46 LVPCVFVIGLLGNSVSIYVLTRKRMRCTTNIYLTALAITDIA-------YLTCQLIL--SLQHYD 101

  Fly    96 KLSYSWACFIKFHSIFAQVLHT---ISIWLTVTLAVWRYIAVGYPQKNRVWCGMRTTIITITTAY 157
            ...|.:..:.:.:..|..:..:   |||::.|...:.|:||:.||.|.:.:|........|....
  Fly   102 YPKYHFKLYWQLYGYFVWLCDSFGYISIYIAVCFTIERFIAIRYPLKRQTFCTESLAKKVIAAVA 166

  Fly   158 VVCVLVVSPSLY--LITAITEYVDQL--DMNGKVINSIPMTQYVIDYRNELLSARTAALNATPTS 218
            :.|:|....:.:  .||..|..:|..  ..|..|.|..||....:        |.|..|...|..
  Fly   167 IFCLLSTLSTAFEHTITIGTRQIDDAYQPCNQTVANISPMPPPPV--------AVTPPLATPPLP 223

  Fly   219 APLNETVWLNASTLLTSTTTAAP---------------------------------PTPSPVV-- 248
            .|  .|:|.:..:.:.|||:.:.                                 ||....:
  Fly   224 TP--ATIWQSPDSAMESTTSGSSNQLVDWGSGSGDGEPENIPRHRRHWQSSGFVTLPTLRKTLEE 286

  Fly   249 -------------------------RNVTVYRLYHSDLALHNAS--LQNATFL-----------I 275
                                     |:...:.:.::|....|.:  .||.|:.           :
  Fly   287 QDQKVADAAQRSGVTESLLQLWRRKRSAENHNINNTDAFAFNVTEYCQNVTYYNHGLSELGYDEL 351

  Fly   276 YS--------VVIKLIPCIALTILSVRLILALLEAKRRRKKLTSKPATPGASNGTKSPANGKAAD 332
            ||        :|..:.|.:.|...:..|||.:..:|..|..||:              |:.....
  Fly   352 YSYLWNLFTLLVFVVFPLLLLATFNSILILLVHRSKNLRGDLTN--------------ASSIRRT 402

  Fly   333 RPRKNSKTLEKEKQTDRTTRMLLAVLLLFLITEFPQGIMGLLNAVLGDVFYLQCYLR----LSDL 393
            :.:.||.......|.:|.|..|:||:|:|::.:.|..|..::|.      |::..:.    ..::
  Fly   403 KRKSNSGLKGSVSQENRVTITLIAVVLMFIVCQLPWAIYLIVNQ------YMEIQIGTQVVAGNV 461

  Fly   394 MDILALINSSINFILYCSMSKQFRTTFTLLFRPKFLDKWLPVAQDEMAAARAERSAVAPVLEKGR 458
            .::||.::::.||.|||.:|.::|.|                .::.:...|..|       ...|
  Fly   462 CNLLASLHAASNFFLYCVLSDKYRKT----------------VRELITGYRYRR-------RHAR 503

  Fly   459 QQPQVVMASTTTNITQVTNLXH----------RRSRGRRTLLS 491
            ....:.:..|||.:||: |..|          ||:|....|::
  Fly   504 NNTSLYVPHTTTTLTQI-NGDHYGSNYGGAGSRRNRNTGRLIA 545

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MsR1	NP_001261324.1	7tm_4	30..427	CDD:304433	105/487 (22%)
Proc-R	NP_001014723.1	7tm_4	52..>183	CDD:304433	38/139 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45467297
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840