Protein Alignment MsR1 and Gpr139

DIOPT Version :10

• Sequence 1: NP_001261324.1
• Gene: MsR1 / 38298
• FlyBaseID: FBgn0035331
• Length: 556
• Species: Drosophila melanogaster
• Sequence 2: NP_001019412.1
• Gene: Gpr139 / 293545
• RGDID: 1311729
• Length: 345
• Species: Rattus norvegicus
• Alignment Length: 409
• Identity: 100/409 - (24%)
• Similarity: 155/409 - (37%)
• Gaps: 148/409 - (36%)

  Fly    30 YVSLVVCILGTIANTLNIIVLTR---REMRSPTNAILTGLAVADLAVM--LEYIPYTIHDYILTD 89
            |.|.::| ||..||.|.:|:|::   |..:|..|.:| .||.||:.|:  :.::.:.:.|:|||.
  Rat    24 YYSFLLC-LGLPANILTVIILSQLVARRQKSSYNYLL-ALAAADILVLFFIVFVDFLLEDFILTM 86

  Fly    90 SLPR-EEKLSYSWACFIKFHSIFAQVLHTISIWLTVTLAVWRYIAVGYPQKNRVWCGMRTTIITI 153
            .:|. .:|:..    .::|.||     || |||:||.|.|.|||||.:|.|.........|...|
  Rat    87 QMPPIPDKIIE----VLEFSSI-----HT-SIWITVPLTVDRYIAVCHPLKYHTVSYPARTRKVI 141

  Fly   154 TTAYVVCVLVVSPSLYLITAITEYVDQLDMNGKVINSIPMTQYVIDYRNELLSARTAALNATPTS 218
            .:.|:.|.|...|..:.....||                  .|:....:.:|
  Rat   142 LSVYITCFLTSIPYYWWPNIWTE------------------DYISTSMHHVL------------- 175

  Fly   219 APLNETVWLNASTLLTSTTTAAPPTPSPVVRNVTVYRLYHSDLALHNASLQNATFLIYSVVIKLI 283
                  ||::.                                           |.:|     |:
  Rat   176 ------VWIHC-------------------------------------------FTVY-----LV 186

  Fly   284 PCIALTILSVRLILALLEAKRRRKKLTSKPATPGASNGTKSPANGKAADRPRKNSKTLEKEKQTD 348
            ||....||:     :::..|.|||   |.....|.|.|
  Rat   187 PCSIFFILN-----SIIVYKLRRK---SNFRLRGYSTG--------------------------- 216

  Fly   349 RTTRMLLAVLLLFLITEFPQGIM---GLLNAVLGDVFYLQCYLRLSDLMDILALINSSINFILYC 410
            :||.:|..:..:|.....|:.||   .|..|.:.:.:.:...|   |:.::|||:|::|||.|||
  Rat   217 KTTAILFTITSIFATLWAPRIIMILYHLYGAPIQNPWLVHIML---DVANMLALLNTAINFFLYC 278

  Fly   411 SMSKQFRT----TFTLLFR 425
            .:||:|||    |...||:
  Rat   279 FISKRFRTMAAATLKALFK 297

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MsR1	NP_001261324.1	7tmA_FMRFamide_R-like	28..420	CDD:410630	97/402 (24%)
		TM helix 1	28..53	CDD:410630	10/25 (40%)
		TM helix 2	59..84	CDD:410630	7/26 (27%)
		TM helix 3	105..135	CDD:410630	16/29 (55%)
		TM helix 4	147..167	CDD:410630	5/19 (26%)
		TM helix 5	269..294	CDD:410630	7/24 (29%)
		TM helix 6	345..375	CDD:410630	8/32 (25%)
		TM helix 7	388..413	CDD:410630	12/24 (50%)
Gpr139	NP_001019412.1	7tmA_GPR139	19..288	CDD:320585	97/398 (24%)
		TM helix 1	20..46	CDD:320585	10/22 (45%)
		TM helix 2	54..79	CDD:320585	7/25 (28%)
		TM helix 3	93..123	CDD:320585	17/39 (44%)
		TM helix 4	135..155	CDD:320585	5/19 (26%)
		TM helix 5	172..197	CDD:320585	10/96 (10%)
		TM helix 6	213..245	CDD:320585	9/58 (16%)
		TM helix 7	256..281	CDD:320585	12/27 (44%)