Protein Alignment MsR1 and srw-103

DIOPT Version :10

• Sequence 1: NP_001261324.1
• Gene: MsR1 / 38298
• FlyBaseID: FBgn0035331
• Length: 556
• Species: Drosophila melanogaster
• Sequence 2: NP_503489.2
• Gene: srw-103 / 191411
• WormBaseID: WBGene00005850
• Length: 368
• Species: Caenorhabditis elegans
• Alignment Length: 472
• Identity: 104/472 - (22%)
• Similarity: 189/472 - (40%)
• Gaps: 153/472 - (32%)

  Fly    17 MDNFHTSYKNMH---------GY----VSLVVCILGTIANTLNIIVLTRREMR-SPTNAILTGLA 67
            |.:....|:|:.         ||    .:.::.::..:.|..:|.:|.|:.|| |.||.||.||:
 Worm     1 MSSPFVDYENLEDVQEVVSGIGYHIHRANFILSLISVLVNLAHITILCRKSMRTSATNVILIGLS 65

  Fly    68 VADLAVMLEYIPYTIHDYILTDSLPREEKLSYS--WACFIKFHSIFAQVLH---TISIWLTVTLA 127
            ::|:.:::.    |::.::........:.::.|  |..::.. ::::..:|   .:| ||.|.:|
 Worm    66 ISDMCIVMT----TVYKHLFMIDFENSDCMTSSLRWKIYVDM-TVWSIQIHFRRCVS-WLGVLMA 124

  Fly   128 VWRYIAV--------GYPQKNRV-WCGMRTTIITITTAYVVCVLVVSPSLYLITAITEYVDQLDM 183
            ..|::.|        |...|.:| |             |:  :||||....|.||..:....:..
 Worm   125 TVRFVIVKKMTTSRFGNWSKPKVGW-------------YM--ILVVSCISALQTAFYQSRWMVVE 174

  Fly   184 NGKVINSIPMTQYVIDYRNELLSARTAALNATPTSAPLNETVWLNASTLLTSTTTAAPPTPSPVV 248
            |    .|||:                          |:|..::...|              ..|.
 Worm   175 N----RSIPL--------------------------PVNCALYQKIS--------------RRVQ 195

  Fly   249 RNVTVYRLYHSDLALHNASLQNATFLIYSVVIKLIPCIALTILSVRLILALLEAKRRRKKLTSKP 313
            .:|.:...::||    :..:..:...:.:||.|.|||:|.:||:|.|:.||.:.|:
 Worm   196 FSVMLNDFFNSD----DQFVLRSYLTVDAVVTKFIPCVAFSILTVLLLHALQKLKK--------- 247

  Fly   314 ATPGASNGTKSPANGKAADRPRKNSKTLEKEKQTDRTTRMLLAVLLLFLITEFPQGIMGLLNAVL 378
              .|.|.|             ||...|.|.:|  |.:|::::.:.:.|||.|.|.|::.|:.|
 Worm   248 --SGESIG-------------RKTGSTNEDKK--DLSTKLIIFMTISFLIIEAPLGVIYLVKA-- 293

  Fly   379 GDVFYLQCYLRLSDLMDILA-----------LINSSINFILYCSMSKQFRTTFTLLFRPKFLDKW 432
                   ||.| :|.:.||:           .:||.|:.|....||.|:|.|         :.|.
 Worm   294 -------CYDR-NDAISILSSDFVVYFSMLVTVNSIIHPIFCILMSSQYRDT---------IRKM 341

  Fly   433 LPVAQDEMAAARAERSA 449
            |.|.:....|::..:::
 Worm   342 LGVTKKTKIASQKNKTS 358

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MsR1	NP_001261324.1	7tmA_FMRFamide_R-like	28..420	CDD:410630	96/430 (22%)
		TM helix 1	28..53	CDD:410630	5/37 (14%)
		TM helix 2	59..84	CDD:410630	8/24 (33%)
		TM helix 3	105..135	CDD:410630	8/40 (20%)
		TM helix 4	147..167	CDD:410630	5/19 (26%)
		TM helix 5	269..294	CDD:410630	9/24 (38%)
		TM helix 6	345..375	CDD:410630	10/29 (34%)
		TM helix 7	388..413	CDD:410630	8/35 (23%)
srw-103	NP_503489.2	7TM_GPCR_Srw	28..345	CDD:402097	97/430 (23%)
		TM helix 2	57..84	CDD:410630	8/30 (27%)
		TM helix 3	102..132	CDD:410630	7/31 (23%)
		TM helix 4	146..169	CDD:410630	10/37 (27%)
		TM helix 5	212..237	CDD:410630	9/24 (38%)
		TM helix 6	262..292	CDD:410630	10/31 (32%)
		TM helix 7	306..331	CDD:410630	4/24 (17%)