Protein Alignment MsR1 and srw-109

DIOPT Version :10

• Sequence 1: NP_001261324.1
• Gene: MsR1 / 38298
• FlyBaseID: FBgn0035331
• Length: 556
• Species: Drosophila melanogaster
• Sequence 2: NP_503261.2
• Gene: srw-109 / 191334
• WormBaseID: WBGene00005856
• Length: 357
• Species: Caenorhabditis elegans
• Alignment Length: 450
• Identity: 96/450 - (21%)
• Similarity: 166/450 - (36%)
• Gaps: 153/450 - (34%)

  Fly    19 NFHTSYKN----MHGY---VSLVVCILGTIANTLNIIVLTRREMR-SPTNAILTGLAVADLAVML 75
            ||...::|    :..|   |..::.|:..|.|.|:.:::||:.:| |..|.::.|:.|.|:..||
 Worm     8 NFIQKFQNVLNLLEKYAFLVQFILAIISFILNLLHFVIITRKSIRISSINCLMVGVTVCDICRML 72

  Fly    76 EYIPYTIHDYILTDSLPREEKLSYSWACFIKFH----SIFAQ-VLHTISIWLTVTLAVWRYIAVG 135
            .    ||:.|:..:.|...|.::.|  .:||.:    |.:.| .....|.||.:.:|..|||.:
 Worm    73 T----TIYRYLELEDLEYPECITVS--SYIKAYLDITSWWLQDYFRRCSSWLDIFIANVRYIIM- 130

  Fly   136 YPQKNRVWCGMRTT--------IITITTAYVVCVLVVSPSLYLITAITEYVDQLDM-------NG 185
                 |...|.|.:        .|.:|..:....|:.|..||.|    :.|::.|:       ..
 Worm   131 -----RKVSGARNSKTAQSKLGFILMTLVFCTSNLIQSMCLYSI----QIVEKRDIFLFSNCAEH 186

  Fly   186 KVINSIPMTQYVIDYRNELLSARTAALNATPTSAPLNETVWLNASTLLTSTTTAAPPTPSPVVRN 250
            :.||.:  .:|.|:.|                                        |.|:
 Worm   187 QDINKV--YKYTINLR----------------------------------------PIPT----- 204

  Fly   251 VTVYRLYHSDLALHNASLQNATFLIYSVVIK-LIPCIALTILSVRLILALLEAKRRRKKLTSKPA 314
                         .|..|...|::...|:.. .:|..|..||:|.|:      ::.:|...|:|.
 Worm   205 -------------DNKMLLIRTYIFLDVIFSHFLPSQAFPILTVLLL------RKIQKMEKSRPV 250

  Fly   315 TPGASNGTKSPANGKAADRPRKNSKTLEKEKQTDRTTRMLLAVLLLFL-ITEFPQGIMGLLNAVL 378
            .                    :|::..|..:.    ...|...|::|| |:.|      |.:|.|
 Worm   251 V--------------------RNNRVAENNED----KHPLSTNLIIFLTISSF------LADAPL 285

  Fly   379 GDVFYLQCYL-----RLSDLMDILALIN--SSINF----ILYCSMSKQFRTTFTLLFRPK 427
            |.:..::.::     |:..|.|::..:|  |:|..    ||..||.:|:|.|....||.|
 Worm   286 GCIVMIKLFIPSGNRRIRFLTDLIVYLNILSTIIIMFRPILCFSMPRQYRNTAKKFFRVK 345

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MsR1	NP_001261324.1	7tmA_FMRFamide_R-like	28..420	CDD:410630	89/428 (21%)
		TM helix 1	28..53	CDD:410630	7/27 (26%)
		TM helix 2	59..84	CDD:410630	8/24 (33%)
		TM helix 3	105..135	CDD:410630	11/34 (32%)
		TM helix 4	147..167	CDD:410630	5/27 (19%)
		TM helix 5	269..294	CDD:410630	6/25 (24%)
		TM helix 6	345..375	CDD:410630	7/30 (23%)
		TM helix 7	388..413	CDD:410630	9/35 (26%)
srw-109	NP_503261.2	TM helix 1	26..48	CDD:410628	5/21 (24%)
		7TM_GPCR_Srw	27..345	CDD:402097	91/429 (21%)
		TM helix 2	57..79	CDD:410628	8/25 (32%)
		TM helix 3	102..124	CDD:410628	5/21 (24%)
		TM helix 4	149..165	CDD:410628	4/15 (27%)
		TM helix 5	212..235	CDD:410628	6/22 (27%)
		TM helix 6	268..291	CDD:410628	9/28 (32%)
		TM helix 7	306..331	CDD:410628	7/24 (29%)