Protein Alignment MsR1 and srw-97

DIOPT Version :10

• Sequence 1: NP_001261324.1
• Gene: MsR1 / 38298
• FlyBaseID: FBgn0035331
• Length: 556
• Species: Drosophila melanogaster
• Sequence 2: NP_494034.1
• Gene: srw-97 / 191118
• WormBaseID: WBGene00005844
• Length: 372
• Species: Caenorhabditis elegans
• Alignment Length: 464
• Identity: 96/464 - (20%)
• Similarity: 165/464 - (35%)
• Gaps: 145/464 - (31%)

  Fly     6 NETEPLYCGSGMDNFHTSYKNMHGYVSLV-------------VCILGTIANTLNIIVLTRREMR- 56
            |:||.:.....|...|.:...::..:.|:             :...|.:....::.:|||:.|.
 Worm     3 NDTEFVTTAEFMFPSHANKLELYRILLLLEQFARPSLWFQFYLSFFGILLTIFHLYILTRKAMMI 67

  Fly    57 SPTNAILTGLAVADLAVMLEYIPYTIHDYI---LTDSLPREE--KLSYSWACFIKFHSIFAQVLH 116
            |...||:.|:|:.|:..||..| .|::.|.   .||..|...  ...:||| ||.....    :.
 Worm    68 SSIIAIMIGIAICDVVAMLAAI-LTVNIYFDEEGTDCTPPVSLFNFQFSWA-FITIRDF----VR 126

  Fly   117 TISIWLTVTLAVWRYIAVGYP--------QKNR------VWCGMRTTIITITTAYVVCVLVVSPS 167
            ..|.||.|.:|:.||:.:.:.        .|.|      .||
 Worm   127 RASTWLAVAMALIRYVIIKFGATMKFDKCSKPRFGFLVIFWC----------------------- 168

  Fly   168 LYLITAITEYVDQLDMNGKVINSIPMTQYVIDYRNELLSARTAALNATPTSAPLNETVWLNASTL 232
             :|.:|....|                 |...|        ...|...|.. |.:....::.|..
 Worm   169 -FLFSAFFSLV-----------------YYFRY--------DFVLKKDPWQ-PKDHCTDVDHSLK 206

  Fly   233 LTSTTTAAPPTPSPVVRNVTVY-----RLYHSDLALHNASLQNATFLIYSVVIKLIPCIALTILS 292
            |.:.|       ..:....|||     ::|.               |:..::.|::|||.|.||:
 Worm   207 LDAFT-------QKLAYIFTVYGGILGKIYQ---------------LVNGILSKILPCILLPILT 249

  Fly   293 VRLILALLEAKRRRKKLTSKPATPGASNGTKSPANGKAADRPRKNSKTLEKEKQTDRTTRMLLAV 357
            :.|||.|                             :.|::.||||.|..|:..:::||.:::.:
 Worm   250 ILLILEL-----------------------------RKAEKNRKNSNTNAKKLTSEKTTGLVIFM 285

  Fly   358 LLLFLITEFPQGIMGLLNAVLGDVFYLQCYLRLSDLMDILALINSSINFILYCSMSKQFRTTFTL 422
            .:.|.:.|.|.||..:......|..||.....::.|::.:.:||:..:..:..|||.|:|.|...
 Worm   286 TISFFLLELPIGIGLVFQVAYTDFGYLYFATYVNHLVNSICIINALTHGAVMFSMSSQYRITVGA 350

  Fly   423 LFRPKFLDK 431
            :.:.|..|:
 Worm   351 MLKVKASDR 359

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MsR1	NP_001261324.1	7tmA_FMRFamide_R-like	28..420	CDD:410630	88/429 (21%)
		TM helix 1	28..53	CDD:410630	4/37 (11%)
		TM helix 2	59..84	CDD:410630	9/24 (38%)
		TM helix 3	105..135	CDD:410630	8/29 (28%)
		TM helix 4	147..167	CDD:410630	0/19 (0%)
		TM helix 5	269..294	CDD:410630	8/24 (33%)
		TM helix 6	345..375	CDD:410630	7/29 (24%)
		TM helix 7	388..413	CDD:410630	4/24 (17%)
srw-97	NP_494034.1	7TM_GPCR_Srw	41..355	CDD:402097	88/420 (21%)
		TM helix 2	70..93	CDD:410628	9/23 (39%)
		TM helix 3	116..138	CDD:410628	8/26 (31%)
		TM helix 4	163..179	CDD:410628	5/56 (9%)
		TM helix 5	213..250	CDD:410628	12/51 (24%)
		TM helix 6	279..301	CDD:410628	6/21 (29%)
		TM helix 7	316..341	CDD:410628	4/24 (17%)