Protein Alignment MsR1 and srw-66

DIOPT Version :10

• Sequence 1: NP_001261324.1
• Gene: MsR1 / 38298
• FlyBaseID: FBgn0035331
• Length: 556
• Species: Drosophila melanogaster
• Sequence 2: NP_493936.2
• Gene: srw-66 / 190359
• WormBaseID: WBGene00005813
• Length: 386
• Species: Caenorhabditis elegans
• Alignment Length: 423
• Identity: 90/423 - (21%)
• Similarity: 162/423 - (38%)
• Gaps: 127/423 - (30%)

  Fly    25 KNMHGYVSLVVCILGTIANTLNIIVLTRREM-RSPTNAILTGLAVADLAVMLEYIPYTIHDYILT 88
            ||.:.:::.|...:    |.:::.:|||:.| .:..|.|:.|:.:.||..|    .|.|:|.|..
 Worm    36 KNAYNWLACVAVFI----NCIHLSILTRKSMGLNSINIIMIGICICDLVNM----SYAIYDIIFL 92

  Fly    89 DSLPREE---KLSYSWACFIKFHSIFAQVLHTISIWLTVTLAVWRYIAVGYPQKNRVWCGMRTTI 150
            ...|.::   .|||:......:...|..:...::.:..|.:.:.|:..:.:        .:....
 Worm    93 IVHPNDKCTPPLSYAMELLDYWLLSFQDITRRMTSFFGVLMTIVRFFIIKF--------ALNRKF 149

  Fly   151 ITITTA-YVVCVLVVSPSLYLITAIT-------EYVDQLD-MNGKVINSIPMTQYVIDYRNELLS 206
            .||:.| :.:|.:.:  ...|.:.||       |:|:... :..|..:..|....|.:|.:.:..
 Worm   150 DTISKARFAICSIAI--GFVLSSGITLFFWLRYEFVEVKPWIPPKKCSQFPPNYTVSEYMSTMAK 212

  Fly   207 ARTAALNATPTSAPLNETVWLNASTLLTSTTTAAPPTPSPVVRNVTVYRLYHSDLALHNASLQNA 271
            |.:.| :.||               |||
 Worm   213 AYSKA-DQTP---------------LLT------------------------------------- 224

  Fly   272 TFLIYSVVIKLIPCIALTILSVRLILALLEAKRRRKKLTSKPATPGASNGTKSPANGKAADRPRK 336
            .|.|...:.|:||.:...|.:..||..|..|...|:|.::       |.|::
 Worm   225 VFTILDGLSKIIPAVIYPIFTFLLIQQLRAAIALRRKTST-------SMGSR------------- 269

  Fly   337 NSKTLEKEKQTDRTTRMLLAVLLLFLITEFPQGIMGLL------NAVLGDVFYLQCYLRLSDLMD 395
                ||..| :|:||:|::.:.:.|.|:|.|.||..:|      .:|..|:.|        ||||
 Worm   270 ----LESTK-SDQTTKMVILMTVTFTISEGPIGICYILEGTLPKRSVFRDINY--------DLMD 321

  Fly   396 ---ILALINSSINFILYCSMSKQFR-TTFTLLF 424
               |...||:|::|::...:..|:| :...|||
 Worm   322 AFTIFVAINASVHFLICLGVHSQYRKSAKELLF 354

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MsR1	NP_001261324.1	7tmA_FMRFamide_R-like	28..420	CDD:410630	85/414 (21%)
		TM helix 1	28..53	CDD:410630	4/24 (17%)
		TM helix 2	59..84	CDD:410630	8/24 (33%)
		TM helix 3	105..135	CDD:410630	3/29 (10%)
		TM helix 4	147..167	CDD:410630	4/20 (20%)
		TM helix 5	269..294	CDD:410630	6/24 (25%)
		TM helix 6	345..375	CDD:410630	12/35 (34%)
		TM helix 7	388..413	CDD:410630	9/27 (33%)
srw-66	NP_493936.2	7TM_GPCR_Srw	41..355	CDD:402097	88/418 (21%)
		TM helix 2	68..92	CDD:410628	10/27 (37%)
		TM helix 3	113..135	CDD:410628	2/21 (10%)
		TM helix 4	160..176	CDD:410628	4/17 (24%)
		TM helix 5	224..246	CDD:410628	7/58 (12%)
		TM helix 6	279..301	CDD:410628	8/21 (38%)
		TM helix 7	317..342	CDD:410628	10/32 (31%)