Protein Alignment MsR1 and srw-99

DIOPT Version :10

• Sequence 1: NP_001261324.1
• Gene: MsR1 / 38298
• FlyBaseID: FBgn0035331
• Length: 556
• Species: Drosophila melanogaster
• Sequence 2: NP_503487.1
• Gene: srw-99 / 189965
• WormBaseID: WBGene00005846
• Length: 356
• Species: Caenorhabditis elegans
• Alignment Length: 419
• Identity: 97/419 - (23%)
• Similarity: 162/419 - (38%)
• Gaps: 121/419 - (28%)

  Fly    26 NMHGYVSLVVCILGTIANTLNIIVLTRREMR-SPTNAILTGLAVADLAVMLEYIPYTIHDYILTD 89
            |...|.:..:|....|.|.|::|||||:.|| :.||.||.|:|.:|:..|    ..|::.:....
 Worm    19 NYAHYANFSLCCFALIINLLHLIVLTRKSMRTTSTNVILIGIAFSDICAM----SATVYKHFEMV 79

  Fly    90 SLPREEKLSYS--WACFIKFHSIFAQVLH--TISIWLTVTLAVWRYIAV---------GYPQKNR 141
            .:...|.|:.:  |..::.. :::|...|  ..|.||.|.||..||:.:         ..|:
 Worm    80 DVENPECLTSNKLWKIYLNM-NVWALQYHFRRCSSWLGVLLASVRYVILKSLTDRSKFAKPK--- 140

  Fly   142 VWCGMRTTIITITTAYVVCVLVVSPSLYLITAITEYVDQLDMNGKVINSIPMTQYVIDYRNELLS 206
              .|.:..|:      |.|   ||.:|.|                          |...|.::|.
 Worm   141 --VGWKLFIV------VQC---VSATLSL--------------------------VYQLRFQVLE 168

  Fly   207 ARTAALNATPTSAPLNETVWLNASTLLTSTTTAAPPTPSPVVRNVTVYRLYHSDLALHNASLQNA 271
            .||..|       |::...:.:.:.....|.:..|...:   .|..|.||:
 Worm   169 DRTIPL-------PISCAEFQDINNASKYTLSLIPLFQN---NNQLVLRLF-------------- 209

  Fly   272 TFLIYSVVIKLIPCIALTILSVRLILALLEAKRRRKKLTSKPATPGASNGTKSPANGKAADRPRK 336
             :|:..:|.:.:||.|..||:    ..||...|:.|||                      |:...
 Worm   210 -YLVNGLVTRDLPCGAFPILT----FFLLRELRKTKKL----------------------DKVSH 247

  Fly   337 NSKTLEKEKQTDRTTRMLLAVLLLFLITEFPQGIMGLLNAVLGDVFYL---QCYLRLSDLM---D 395
            .|.|:::.:...:||:.::.:...:.|.|.|.||:.|:.     ||:.   :.||...||:   .
 Worm   248 RSNTIDRSEARHKTTKCIVFMTNAYFIAEAPMGIISLVK-----VFFNTDDRVYLISVDLVIYFT 307

  Fly   396 ILALINSSINFILYCSMSKQFRTTFTLLF 424
            :|..|||..:.::...||.|:|.|...:|
 Worm   308 LLLTINSICHSVICFMMSTQYRKTIWKMF 336

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MsR1	NP_001261324.1	7tmA_FMRFamide_R-like	28..420	CDD:410630	94/411 (23%)
		TM helix 1	28..53	CDD:410630	9/24 (38%)
		TM helix 2	59..84	CDD:410630	9/24 (38%)
		TM helix 3	105..135	CDD:410630	10/40 (25%)
		TM helix 4	147..167	CDD:410630	5/19 (26%)
		TM helix 5	269..294	CDD:410630	7/24 (29%)
		TM helix 6	345..375	CDD:410630	8/29 (28%)
		TM helix 7	388..413	CDD:410630	7/27 (26%)
srw-99	NP_503487.1	7TM_GPCR_Srw	23..339	CDD:402097	96/415 (23%)
		TM helix 1	23..46	CDD:410630	9/22 (41%)
		TM helix 2	53..78	CDD:410630	9/28 (32%)
		TM helix 3	98..128	CDD:410630	10/30 (33%)
		TM helix 4	140..160	CDD:410630	8/59 (14%)
		TM helix 5	206..231	CDD:410630	9/43 (21%)
		TM helix 6	258..286	CDD:410630	8/27 (30%)
		TM helix 7	299..325	CDD:410630	6/25 (24%)