Protein Alignment MsR1 and srw-54

DIOPT Version :10

• Sequence 1: NP_001261324.1
• Gene: MsR1 / 38298
• FlyBaseID: FBgn0035331
• Length: 556
• Species: Drosophila melanogaster
• Sequence 2: NP_507202.1
• Gene: srw-54 / 189573
• WormBaseID: WBGene00005801
• Length: 351
• Species: Caenorhabditis elegans
• Alignment Length: 405
• Identity: 84/405 - (20%)
• Similarity: 146/405 - (36%)
• Gaps: 130/405 - (32%)

  Fly    30 YVSLVVCILGTIANTLNIIVLTRREMRSPT-NAILTGLAVADLAVMLEYIPYTIHDYILTDSLPR 93
            |.:..:.::|.|||..::|||.|:.||:.| |..:.|:|:.:...|:.|:...|..|     ..:
 Worm    39 YFNFSISVVGVIANIFHLIVLGRKSMRALTVNTFMMGIAICEFVRMMCYVIMRIPKY-----YRK 98

  Fly    94 EEKL----------SYSWACFIKFHSIFAQVLHTISIWLTVTLAVWRYIAVGYPQKNRVWCGMRT 148
            .:|.          ||...|.:...||....:....|.:.|.:||.|.:::.||..:::
 Worm    99 YQKFKFGRFCVPPDSYLTICIVNNSSILFNSIQDPLISIAVAMAVLRTVSLKYPMSSKI------ 157

  Fly   149 TIITITTAYVVCVLVVSPSLYLITAITEYVDQLDMNGKVINSIPMTQYVIDYRNELLSARTAALN 213
                               |.:|..||               ||.  :.:|:..
 Worm   158 -------------------LLIIRGIT---------------IPF--WALDFSQ----------- 175

  Fly   214 ATPTSAPLNETVWLNASTLLTSTTTAAPPTPSP-VVRNVTVYRLYHSDLALHNASLQNATF--LI 275
                                |..|..:.|...| ..::....|.|.|.    ..||||..|  ||
 Worm   176 --------------------TQVTVESDPWRLPDDCKHFAEGRFYFST----TTSLQNQGFVLLI 216

  Fly   276 YSVVIKLIPCIALTILSVRLILALLEAKRRRKKLTSKPATPGASNGTKSPANGKAADRPRKNSKT 340
            ..::.|||..:.|.|.:    |.|:...:.|.|::|..::  |||
 Worm   217 QGILFKLILSLVLPIAT----LILIHDIKMRNKVSSVGSS--ASN-------------------- 255

  Fly   341 LEKEKQTDRTTRMLLAVLLLFLITEFPQGIMGLLN-AVLGDVFYLQCYLRLSDLMDILALINSSI 404
                   ||:|.:::.:.:.|:|...|||::.|:. ....|...:.....|::....:.|.|.:|
 Worm   256 -------DRSTNLVVFMTISFIIALAPQGVLYLIKFTYKNDEGVVSTIETLNNFHAFVPLANGTI 313

  Fly   405 NFILYCSMSKQFRTT 419
            :.|:...:|..:|.|
 Worm   314 HIIINFFISSMYRRT 328

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MsR1	NP_001261324.1	7tmA_FMRFamide_R-like	28..420	CDD:410630	84/405 (21%)
		TM helix 1	28..53	CDD:410630	8/22 (36%)
		TM helix 2	59..84	CDD:410630	7/25 (28%)
		TM helix 3	105..135	CDD:410630	7/29 (24%)
		TM helix 4	147..167	CDD:410630	0/19 (0%)
		TM helix 5	269..294	CDD:410630	10/26 (38%)
		TM helix 6	345..375	CDD:410630	9/29 (31%)
		TM helix 7	388..413	CDD:410630	5/24 (21%)
srw-54	NP_507202.1	7TM_GPCR_Srw	39..336	CDD:402097	84/405 (21%)
		TM helix 1	39..61	CDD:410628	8/21 (38%)
		TM helix 2	70..92	CDD:410628	5/21 (24%)
		TM helix 3	121..143	CDD:410628	4/21 (19%)
		TM helix 5	202..234	CDD:410628	13/39 (33%)
		TM helix 6	259..281	CDD:410628	6/21 (29%)
		TM helix 7	294..322	CDD:410628	5/27 (19%)