Protein Alignment MsR1 and srw-77

DIOPT Version :10

• Sequence 1: NP_001261324.1
• Gene: MsR1 / 38298
• FlyBaseID: FBgn0035331
• Length: 556
• Species: Drosophila melanogaster
• Sequence 2: NP_507211.1
• Gene: srw-77 / 189258
• WormBaseID: WBGene00005824
• Length: 349
• Species: Caenorhabditis elegans
• Alignment Length: 417
• Identity: 85/417 - (20%)
• Similarity: 147/417 - (35%)
• Gaps: 131/417 - (31%)

  Fly    31 VSLVVCILGTIANTLNIIVLTRREMR-SPTNAILTGLAVADLAVMLEYIPYTIHDYILTDSLPRE 94
            |..|:.|:|.|....::::|||:.|| |.||:|:||:|:.||.|:||.:...::.:.:.|: |..
 Worm    19 VQFVIAIVGFILTIPHLLILTRKSMRSSSTNSIMTGIAILDLVVLLEVVLEHVYYFWIYDN-PCI 82

  Fly    95 EKLSYSWACFIKFHSIFAQVLHTISIWLTVTLAVWRYIAVGYPQKNRVWCGMRTTIITITTAYVV 159
            ...:|::..|:.............|.|:.|.|.:.|.:...:....|: .|........|..:::
 Worm    83 NHSNYNFELFLWIGDFLKDTGERASFWMGVFLVLIRLLITKFKTAQRL-SGYFFGYAVFTLTFII 146

  Fly   160 CVLVVSPSLYLITAITEYVDQLDMNGKVINSIPMTQYVIDYRNELLSARTAALNATPTSAPLNET 224
            .||:   |.|.                             |....|.|
 Worm   147 NVLI---SYYF-----------------------------YSKFYLQA----------------- 162

  Fly   225 VWLNASTLLTSTTTAAPPTPS------PVVRNVTVYRLYHSDLALHNASLQNATFLIYSVV---I 280
             |:            .|..|.      |...:..:|.....|.|.:.|...|     ||::   .
 Worm   163 -WM------------VPWQPGKRCSEFPKGYSENLYVRTIQDQASYMAVFGN-----YSIIGGMS 209

  Fly   281 KLIPCIALTILSVRLILALLEAKRRRKKLTSKPATPGASNGTKSPANGKAADRPRKNSKTLEKEK 345
            |::..:...:|:|.||..:                      .||..:...|     |||...||:
 Worm   210 KILISVLYPVLAVFLIFDI----------------------RKSAKHASTA-----NSKKAAKER 247

  Fly   346 QTDRTTRMLLAVLLLFLITEFPQGIMGLLNAVLGDVFYLQCYLRLSD-------------LMDIL 397
            .  .|.||:|.:.:|:.||..|.||..          ::..|.::.|             .:..|
 Worm   248 Y--HTGRMILLMAVLYTITSAPGGISK----------FITLYCKVPDGSILMLLIGYGSIFLSAL 300

  Fly   398 ALINSSINFILYCSMSKQFRTTFTLLF 424
            ..:||:.:.::..|||..:|....::|
 Worm   301 FCLNSASHCLINFSMSTNYRKAAKMVF 327

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MsR1	NP_001261324.1	7tmA_FMRFamide_R-like	28..420	CDD:410630	84/411 (20%)
		TM helix 1	28..53	CDD:410630	7/21 (33%)
		TM helix 2	59..84	CDD:410630	11/24 (46%)
		TM helix 3	105..135	CDD:410630	5/29 (17%)
		TM helix 4	147..167	CDD:410630	3/19 (16%)
		TM helix 5	269..294	CDD:410630	5/27 (19%)
		TM helix 6	345..375	CDD:410630	10/29 (34%)
		TM helix 7	388..413	CDD:410630	5/37 (14%)
srw-77	NP_507211.1	TM helix 1	16..40	CDD:410628	6/20 (30%)
		7TM_GPCR_Srw	18..328	CDD:402097	85/417 (20%)
		TM helix 2	49..70	CDD:410628	10/20 (50%)
		TM helix 3	94..116	CDD:410628	4/21 (19%)
		TM helix 4	140..156	CDD:410628	5/47 (11%)
		TM helix 5	198..222	CDD:410628	5/28 (18%)
		TM helix 6	251..273	CDD:410628	9/31 (29%)
		TM helix 7	288..316	CDD:410628	4/27 (15%)