Protein Alignment MsR1 and srw-76

DIOPT Version :10

• Sequence 1: NP_001261324.1
• Gene: MsR1 / 38298
• FlyBaseID: FBgn0035331
• Length: 556
• Species: Drosophila melanogaster
• Sequence 2: NP_507209.2
• Gene: srw-76 / 189256
• WormBaseID: WBGene00005823
• Length: 342
• Species: Caenorhabditis elegans
• Alignment Length: 438
• Identity: 84/438 - (19%)
• Similarity: 154/438 - (35%)
• Gaps: 149/438 - (34%)

  Fly    31 VSLVVCILGTIANTLNIIVLTRREMR-SPTNAILTGLAVADLAVMLEYIP-----YTIHDYILTD 89
            :..:|.|:|.|....::.:|||:.|| |.||:|:||:|:.||.|:|:.|.     :..||.
 Worm    19 IQFLVSIVGFILTLPHLFILTRKSMRTSSTNSIMTGIAIIDLVVLLQVILERGLWFLTHDS---- 79

  Fly    90 SLPREEKLSYSWACFIKFHSIFAQVLHTI-----------SIWLTVTLAVWRYIAVGYPQKNRVW 143
                        .| |..||...::...|           |.|:.|.|.:.|.:....|:...
 Worm    80 ------------PC-INLHSFIFEMFFWIGDFLRDTGERASFWMGVFLVLVRLLITKIPESTE-- 129

  Fly   144 CGMRTTIITITTAYVVCVLVVSPSLYLITAITEYVDQLDMNGKVINSIPMTQYVIDYRNELLSAR 208
                 .:.:....|::.:|:::                      ::|:....|..:|.
 Worm   130 -----RLSSYAFGYLIFILMLT----------------------VHSLISYSYYREYH------- 160

  Fly   209 TAALNATPTSAPLNETVWLNASTLLTSTTTAAPP--TPSPVVRNVTVYRLYHSDLALHNASLQNA 271
                        |.::.||..     ...|..|.  .....:|||       .|...::|.:::.
 Worm   161 ------------LEDSTWLPG-----EECTEYPEGYIEKGYIRNV-------QDQDNYSAIIEDY 201

  Fly   272 TFLIYSVVIKLIPCIALTILSVRLILALLEAKRRRKKLTSKPATPGASNGTKSPANGKAADRPRK 336
            .|  ...:.|::..|...:|::.||..:    |:..::.|                   |....|
 Worm   202 KF--NDGMSKILISILYPVLAIFLIFDI----RKSARIAS-------------------AAHSEK 241

  Fly   337 NSKTLEKEKQTDRTTRMLLAVLLLFLITEFPQGIMGLLNAVLGDVFYLQCYLRLSDLMDI----- 396
            |:      |:...:.||:|.:.:.:.||..|.||        .|...:.|.:....:|.|
 Worm   242 NA------KERYHSGRMILLMTIFYTITSAPGGI--------SDFIQIYCQVPTHSIMTIIIAYG 292

  Fly   397 ------LALINSSINFILYCSMSKQFRTTFTLLF---RPKFLDKWLPV 435
                  |..:||:.:.::..|||..:|....::|   |.:.....||:
 Worm   293 SIFLSALFCLNSASHCLINFSMSTNYRKAAKMVFFANRKQMNTSVLPI 340

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MsR1	NP_001261324.1	7tmA_FMRFamide_R-like	28..420	CDD:410630	80/418 (19%)
		TM helix 1	28..53	CDD:410630	6/21 (29%)
		TM helix 2	59..84	CDD:410630	11/29 (38%)
		TM helix 3	105..135	CDD:410630	9/40 (23%)
		TM helix 4	147..167	CDD:410630	2/19 (11%)
		TM helix 5	269..294	CDD:410630	4/24 (17%)
		TM helix 6	345..375	CDD:410630	9/29 (31%)
		TM helix 7	388..413	CDD:410630	6/35 (17%)
srw-76	NP_507209.2	7TM_GPCR_Srw	18..327	CDD:402097	80/423 (19%)
		TM helix 1	19..40	CDD:410628	5/20 (25%)
		TM helix 2	49..71	CDD:410628	10/21 (48%)
		TM helix 3	94..116	CDD:410628	5/21 (24%)
		TM helix 4	139..155	CDD:410628	2/37 (5%)
		TM helix 5	197..221	CDD:410628	4/25 (16%)
		TM helix 6	251..272	CDD:410628	8/28 (29%)
		TM helix 7	289..315	CDD:410628	4/25 (16%)