Protein Alignment MsR1 and srw-33

DIOPT Version :10

• Sequence 1: NP_001261324.1
• Gene: MsR1 / 38298
• FlyBaseID: FBgn0035331
• Length: 556
• Species: Drosophila melanogaster
• Sequence 2: NP_506844.1
• Gene: srw-33 / 188958
• WormBaseID: WBGene00005780
• Length: 378
• Species: Caenorhabditis elegans
• Alignment Length: 449
• Identity: 98/449 - (21%)
• Similarity: 174/449 - (38%)
• Gaps: 129/449 - (28%)

  Fly     6 NETEPLYCG---------SGMDNFHTSYKNMHGYVSLVVCILGTIANTLNIIVLTRREMRSPT-N 60
            |.:..||.|         :.:|........:...:|.::.|:|.:....:||||:|:.||:.| |
 Worm     2 NSSNDLYPGFSDEDIKFWTEIDELLAVLSILFNMLSFLISIIGILPTIFHIIVLSRKSMRTLTIN 66

  Fly    61 AILTGLAVADLAVMLEYIP-----YTIHDYILTDSLPREEKLS---YSWACFIKFHSIFAQVLHT 117
            |.|.|:.:.|||.|:..|.     ||.|    ...|...|.:|   ||...|........:::..
 Worm    67 AFLLGIGICDLARMMFIIMVLGPLYTEH----FSHLEHPECMSPNYYSTILFALISGFTGKLVEY 127

  Fly   118 ISIWLTVTLAVWRYIAVGYPQKNRVWCGMRTTIITITTAYVVCVLVVSPSLYLITAITEYVDQLD 182
            :||||.|.:|:.|.:.:.||..:|:       ...|.:.|.:.|      |:|||...
 Worm   128 LSIWLAVAMAIIRSLVIKYPLNSRI-------SDLIESKYGIRV------LFLITLPI------- 172

  Fly   183 MNGKVINSIP-MTQYVIDYRNELLSARTAALNATPTSAPLNETVWLNASTLLTSTTTAAPPTPSP 246
                :|.||| ..:|.|.                    |.. ::|:             ||
 Worm   173 ----IILSIPKYFRYSIQ--------------------PFG-SLWV-------------PP---- 195

  Fly   247 VVRNVT-----VYRLYHSDLALHNASLQNATFL--IYSVVIKLIPCIALTILSVRLILALLEAKR 304
              :|.|     .:::.::.:..|... ::..||  :..|:..:||.|.|.|.::.||..|..:::
 Worm   196 --QNCTDFPKNYFQIQYTYVETHIFE-KSTDFLTGMEGVLYVIIPSILLPISTLILIFQLRISRK 257

  Fly   305 RRKKLTSKPATPGASNGTKSPANGKAADRPRKNSKTLEKEKQTDRTTRMLLAVLLLFLITEFPQG 369
            :.:.|.....:.|                              ||||:::..:.:.|.|:..|.|
 Worm   258 KSEALRHTSNSGG------------------------------DRTTKLVTFMTISFTISTAPFG 292

  Fly   370 IMGLLNAVLGDVFYLQ----CYLRLSDLMDILALINSSINFILYCSMSKQFRTTFTLLF 424
            |:.|:..::.:....:    ...|::.|..::..||.:|:|.|...:|.|:|.....:|
 Worm   293 ILHLVKVIVSEAIGSEGMNLIVDRIASLFPLIITINGAIHFFLCYFLSSQYRDAVREMF 351

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MsR1	NP_001261324.1	7tmA_FMRFamide_R-like	28..420	CDD:410630	92/412 (22%)
		TM helix 1	28..53	CDD:410630	7/24 (29%)
		TM helix 2	59..84	CDD:410630	12/30 (40%)
		TM helix 3	105..135	CDD:410630	7/29 (24%)
		TM helix 4	147..167	CDD:410630	3/19 (16%)
		TM helix 5	269..294	CDD:410630	8/26 (31%)
		TM helix 6	345..375	CDD:410630	10/29 (34%)
		TM helix 7	388..413	CDD:410630	7/24 (29%)
srw-33	NP_506844.1	TM helix 1	32..58	CDD:410630	7/25 (28%)
		7TM_GPCR_Srw	36..354	CDD:402097	93/415 (22%)
		TM helix 2	65..90	CDD:410630	9/24 (38%)
		TM helix 3	110..145	CDD:410630	9/34 (26%)
		TM helix 4	159..179	CDD:410630	9/36 (25%)
		TM helix 5	222..247	CDD:410630	8/24 (33%)
		TM helix 6	268..298	CDD:410630	11/59 (19%)
		TM helix 7	311..340	CDD:410630	7/28 (25%)