Protein Alignment MsR1 and dmsr-15

DIOPT Version :9

• Sequence 1: NP_001261324.1
• Gene: MsR1 / 38298
• FlyBaseID: FBgn0035331
• Length: 556
• Species: Drosophila melanogaster
• Sequence 2: NP_001343647.1
• Gene: dmsr-15 / 188523
• WormBaseID: WBGene00020525
• Length: 385
• Species: Caenorhabditis elegans
• Alignment Length: 433
• Identity: 87/433 - (20%)
• Similarity: 162/433 - (37%)
• Gaps: 121/433 - (27%)

  Fly    19 NFHTSYKNMHGYVSLVVCILGTIANTLNIIVLTRREMRSPTNAI-LTGLAVADLAVMLEYIPYTI 82
            :|..:|..:|.|..:...:|....|...|:||:::|:|  |:.| ||.:.:|    :..:...|:
 Worm    62 SFFEAYNPLHIYFLVFFTVLDFFCNISFIVVLSQKELR--TSGINLTMIMIA----LCNFSSVTL 120

  Fly    83 HDYILTDSLPREEKLSYSWACFIKFHSIFAQVLHTISIWLTVTLAVWRYIAVGYPQKNRVWCGMR 147
            :.:.....|..||  :|..|.:....:.....:..::.:|.|.:...|.:|: |...:: |.| |
 Worm   121 NLFDKMLKLLSEE--TYLRALYNYLENFLNLYVPVMADYLVVQMTFCRVMAL-YSNSDK-WKG-R 180

  Fly   148 TTIITITTAYVVCVLVVSPSLYLITAITEYVDQLDMNGKVINSIPMTQYVIDYRNELLSARTAAL 212
            ...:||:....:.:.::|.::..||.|     :..:.||...:|| .:|
 Worm   181 KVAVTISAVLWIFIGMLSSAVLEITEI-----EKTLTGKYAVTIP-DEY---------------- 223

  Fly   213 NATPTSAPLNETVWLNASTLLTSTTTAAPPTPSPVVRNVTVYRLYHSDLALHNASLQNATFLIYS 277
                                              :.....|:|:               :.|.|.
 Worm   224 ----------------------------------IENGCIVFRM---------------SLLFYG 239

  Fly   278 VVIKLIPCIALTILSVRLILALLEAKRRRKKLTSKPATPGASNGTKSPANGKAADRPRKNSKTLE 342
            ::..::|.:.|.|..:.::..|...|..|||...|.::.|..|
 Worm   240 ILFDIVPLLLLFIFFLLILCKLNSFKAHRKKTMGKSSSSGIEN---------------------- 282

  Fly   343 KEKQTDRTTRMLLAVLLLFLITEFPQGIMGLLNAVLGDVFYLQCYLRLSDLMDILALINSSINFI 407
                   ::|:|..||::|.:.:.|...:.:.:||....:|:.........::||...|:|.:||
 Worm   283 -------SSRLLQVVLIMFFLVKIPSAAVTIFSAVYMIDYYMFVKKWTFQFIEILLTFNASTSFI 340

  Fly   408 LYCSMSKQFRTTFTLLFRP---------KFLDKWLPVAQDEMA 441
            :||.||.|||..|..||.|         |.:...|.|...:||
 Worm   341 IYCIMSSQFREIFVRLFVPESVKQRMQSKIMKNSLVVTTRKMA 383

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MsR1	NP_001261324.1	7tm_4	30..427	CDD:304433	79/406 (19%)
dmsr-15	NP_001343647.1	7tm_GPCRs	69..353	CDD:391938	76/394 (19%)
		TM helix 1	70..96	CDD:341315	7/25 (28%)
		TM helix 2	103..128	CDD:341315	5/28 (18%)
		TM helix 3	141..171	CDD:341315	4/30 (13%)
		TM helix 4	181..201	CDD:341315	3/19 (16%)
		TM helix 5	231..256	CDD:341315	6/39 (15%)
		TM helix 6	283..308	CDD:341315	6/24 (25%)
		TM helix 7	325..346	CDD:341315	8/20 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_2BWNV
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	3	2.770