Protein Alignment MsR1 and srw-79

DIOPT Version :10

• Sequence 1: NP_001261324.1
• Gene: MsR1 / 38298
• FlyBaseID: FBgn0035331
• Length: 556
• Species: Drosophila melanogaster
• Sequence 2: NP_001364795.1
• Gene: srw-79 / 188412
• WormBaseID: WBGene00005826
• Length: 349
• Species: Caenorhabditis elegans
• Alignment Length: 478
• Identity: 96/478 - (20%)
• Similarity: 163/478 - (34%)
• Gaps: 151/478 - (31%)

  Fly    16 GMDNFHTSYKNMHGYVSLVVCI------LGTIANTLNIIVLTRREMR-SPTNAILTGLAVADLAV 73
            |:|  :..|:|....||.:..:      .|.|.|..:|.:|||..|| |.||:::.|:|:.|:..
 Worm     4 GLD--YPVYENFKNIVSEIDVVQNYASTAGVIMNIPHIFILTRSSMRTSSTNSLMIGIAICDILY 66

  Fly    74 MLEYIPYTIHDYILTDSLPREEKLSYSWACFIKFHSIFAQVLHTISIWLTVTLAVWRYIAV---G 135
            :.......|.:...:|.|..... ||::............::...|.||...||:.|||.:   |
 Worm    67 LSILAELWIRNAYFSDFLCINVG-SYAYIVSAWILECLRDLIEKASFWLGFMLAMTRYIIMKSSG 130

  Fly   136 YPQKNRVWCGMRTTIITITTAYVVCVLVVSPSLYLITAITEYVDQLDMNGKVINSIPMTQYVIDY 200
            ...|                      |....|.||||.|.          .||::.....|...|
 Worm   131 RADK----------------------LARPSSGYLITFII----------SVISAALSGWYYGRY 163

  Fly   201 RNELLSARTAALNATPTSAPLNETVWLNASTLLTSTTTAAPPTPSPVVRNVTVYRLYHSDLALHN 265
            ..|                 .::.:|:........         .|.|:.:. |.|...|.|:|:
 Worm   164 YLE-----------------KDQNLWIMWDECAGY---------RPKVKGIR-YFLVMDDAAIHS 201

  Fly   266 ASLQNATFLIYSVVIKLIPCIALTILSVRLILALLEAKRRRKKLTSKPATPGASNGTKSPANGKA 330
            .|......:..:::..|.|.|.        :|.::|.:|..|..
 Worm   202 RSHTIINAISRTLISFLYPIIG--------VLLMVEIRRSAKFA--------------------- 237

  Fly   331 ADRPRKNSKTLEKEKQ-TDR--TTRMLLAVLLLFLITEFPQGIMGLLNAVLGDVFYLQCYLRLS- 391
                   :|.|:.||. |:|  .:||:|.:.:::.:...|.|.:..:|  :.::.....:||||
 Worm   238 -------AKKLKSEKSATERYHASRMILVMTVMYFLASAPIGALDFIN--VSEIVTESSFLRLSL 293

  Fly   392 ----DLMDILALINSSINFILYCSMSKQFRTTFTLLFRPKFLDKWLPVAQDEMAAARAERSAVAP 452
                .||..:..:||:.:.|:..|||..:|.|..:        .|:
 Worm   294 DHSAYLMSAIFCLNSASHCIINLSMSSAYRNTIKM--------SWM------------------- 331

  Fly   453 VLEKGRQQPQVVMASTTTNITQV 475
                  :.|:.|...|.|.|..:
 Worm   332 ------RSPKSVKIFTVTRIKSI 348

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MsR1	NP_001261324.1	7tmA_FMRFamide_R-like	28..420	CDD:410630	85/409 (21%)
		TM helix 1	28..53	CDD:410630	8/30 (27%)
		TM helix 2	59..84	CDD:410630	6/24 (25%)
		TM helix 3	105..135	CDD:410630	8/32 (25%)
		TM helix 4	147..167	CDD:410630	1/19 (5%)
		TM helix 5	269..294	CDD:410630	3/24 (13%)
		TM helix 6	345..375	CDD:410630	8/32 (25%)
		TM helix 7	388..413	CDD:410630	10/29 (34%)
srw-79	NP_001364795.1	7TM_GPCR_Srw	23..328	CDD:402097	84/402 (21%)
		TM helix 2	53..75	CDD:410628	4/21 (19%)
		TM helix 3	98..120	CDD:410628	4/21 (19%)
		TM helix 4	143..159	CDD:410628	6/25 (24%)
		TM helix 5	193..224	CDD:410628	7/38 (18%)
		TM helix 6	254..279	CDD:410628	6/26 (23%)
		TM helix 7	294..319	CDD:410628	6/24 (25%)