Protein Alignment MsR1 and srw-53

DIOPT Version :10

• Sequence 1: NP_001261324.1
• Gene: MsR1 / 38298
• FlyBaseID: FBgn0035331
• Length: 556
• Species: Drosophila melanogaster
• Sequence 2: NP_506994.1
• Gene: srw-53 / 188147
• WormBaseID: WBGene00005800
• Length: 341
• Species: Caenorhabditis elegans
• Alignment Length: 427
• Identity: 90/427 - (21%)
• Similarity: 169/427 - (39%)
• Gaps: 134/427 - (31%)

  Fly    22 TSYKNMHGYVSLVVCILGTIANTLNIIVLTRREMRSPT-NAILTGLAVADL----AVMLEYIPYT 81
            |.|:.:  |:..::.|:|..||.:::::|.|:.:|..| ...|.|:::.||    :.::|.:.:.
 Worm    20 THYQQL--YLEPILSIIGFFANIVHLLILIRKPLRIFTIYLFLMGISICDLCRLTSCIIESLRFY 82

  Fly    82 IHDY---ILTDSL--PREEKLSYSWACFIKFHSIFAQVLHTISIWLTVTLAVWRYIAVGYPQKNR 141
            ...|   ||.:..  ||...||:    .:.:....:::...:|:||.||:|:.|::||.||...|
 Worm    83 YDSYQLSILAEKCIPPRSYLLSF----ILLYSDALSKISQKLSVWLGVTMAMLRFLAVKYPMNRR 143

  Fly   142 VWCGMRTTIITITTAYVVCVLVVSPSLYLITAITEYVDQLDMNGKVINSIPMTQY-VIDYRNELL 205
            |    :|.|.:...|.||.::.:....:.|                   |...|| :|:|.
 Worm   144 V----QTLINSNYGARVVLLICLLQLPFWI-------------------IDFLQYEIIEYE---- 181

  Fly   206 SARTAALNATPTSAPLNETVWLNASTLLTSTTTAAPPTPSPVVRNVTVYRLYHSDLALHNASLQN 270
                               :|..|             |..|...|.:...:|..:..:    :.|
 Worm   182 -------------------LWTIA-------------TDCPNYYNNSTQVVYFQNFRM----IVN 210

  Fly   271 ATF-LIYSVVIKLIPCIALTILSVRLILALLEAKRRRKKLTSKPATPGASNGTKSPANGKAADRP 334
            ||. .|..:::..||.|.|.:.:..||..|    :|.||:|...::.|.::..||
 Worm   211 ATVRTIQGLLVTAIPSIMLVVATGMLIYQL----KRIKKVTVLRSSHGNNSHEKS---------- 261

  Fly   335 RKNSKTLEKEKQTDRTTRMLLAVLLLFLITEFPQGIMGLLNAVLGDVFYLQCYL----------- 388
                            |::::.|.:.|:|:..|.|           |:||..|.
 Worm   262 ----------------TKLVITVTISFIISTVPTG-----------VWYLIEYKAFNYGTIVLIV 299

  Fly   389 -RLSDLMDILALINSSINFILYCSMSKQFRTTFTLLF 424
             .:|...::.|:.|.:::|:|...:..|:|.::..||
 Worm   300 DEISAFCELFAIANGTVHFLLCLFLCSQYRKSYKELF 336

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MsR1	NP_001261324.1	7tmA_FMRFamide_R-like	28..420	CDD:410630	86/415 (21%)
		TM helix 1	28..53	CDD:410630	6/24 (25%)
		TM helix 2	59..84	CDD:410630	6/29 (21%)
		TM helix 3	105..135	CDD:410630	8/29 (28%)
		TM helix 4	147..167	CDD:410630	5/19 (26%)
		TM helix 5	269..294	CDD:410630	8/25 (32%)
		TM helix 6	345..375	CDD:410630	6/29 (21%)
		TM helix 7	388..413	CDD:410630	5/36 (14%)
srw-53	NP_506994.1	7TM_GPCR_Srw	26..339	CDD:402097	88/419 (21%)
		TM helix 1	26..49	CDD:410630	6/22 (27%)
		TM helix 2	56..81	CDD:410630	5/24 (21%)
		TM helix 3	107..137	CDD:410630	8/29 (28%)
		TM helix 4	151..171	CDD:410630	4/38 (11%)
		TM helix 5	210..235	CDD:410630	8/24 (33%)
		TM helix 6	262..286	CDD:410630	9/34 (26%)
		TM helix 7	300..325	CDD:410630	5/24 (21%)