Protein Alignment MsR1 and srw-134

DIOPT Version :10

• Sequence 1: NP_001261324.1
• Gene: MsR1 / 38298
• FlyBaseID: FBgn0035331
• Length: 556
• Species: Drosophila melanogaster
• Sequence 2: NP_001309503.1
• Gene: srw-134 / 188103
• WormBaseID: WBGene00005881
• Length: 348
• Species: Caenorhabditis elegans
• Alignment Length: 422
• Identity: 103/422 - (24%)
• Similarity: 159/422 - (37%)
• Gaps: 133/422 - (31%)

  Fly    22 TSYKNMHGYVSLVVCILGTIANTLNIIVLTRREMR-SPTNAILTGLAVADLAVMLEYIPYTIHDY 85
            |||:    |::.|||.|   .|.::|:||||:.|| |..|..:|.:|:           |.|..:
 Worm    38 TSYE----YIASVVCFL---INIVHILVLTRKSMRTSCINITMTAVAI-----------YDIFSF 84

  Fly    86 ILTDSLPREEKLSYSWACF--IKFHSIFAQVL--------HTISIWLTVTLAVWRYIAVGYPQKN 140
            ..|..:...|.:|....||  :.:|.:...:|        ...|.||..::||.|.:.:..|...
 Worm    85 FSTFEVTAIEIISRYSKCFNTMSYHLVSVDLLLYLVNQYARRCSTWLLFSVAVIRTLVLRNPMNP 149

  Fly   141 RVWCGMRTTIITITTAYVVCVLVVSPSLYLITAITEYVDQLDMNGKVINSIPMTQYVIDYRNELL 205
            :.     |.:...:||..|        ::.::||.           :|.||
 Worm   150 KY-----TELSKPSTALRV--------IFGVSAIC-----------IIFSI-------------- 176

  Fly   206 SARTAALNATPTSAPLNETVWLNASTLLTSTTTAAPPTPSPV-VRNVTVYRLYHSDLALHNAS-- 267
                                    ||:..:........||.. ...|.:|....|||.|.|..
 Worm   177 ------------------------STVFENDVGVVGKQPSKCSSHGVLMYAFTISDLFLLNDGLL 217

  Fly   268 LQNATFLIYSVVIKLIPCIALTILSVRLILALLEAKRRRKKLTSKPATPGASNGTKSPANGKAAD 332
            |:.:||.. ::|..:||||...|::|.|:      |..||                       .|
 Worm   218 LKVSTFTA-AIVSHIIPCIIFPIITVLLV------KELRK-----------------------TD 252

  Fly   333 RPRKNSKTLEKEKQTDRTTRMLLAVLLLFLITEFPQGIMGLLNAVLGDVFYLQ-----CYLRLSD 392
            ..||||.:.:|...:.:||:::....:||||.|||.|:...:.....||..||     |..
 Worm   253 ERRKNSTSSKKITDSRKTTKLVFYNTILFLIAEFPLGVSMAITWFFVDVPGLQLICNHCLF---- 313

  Fly   393 LMDILALINSSINFILYCSMSKQFRTTFTLLF 424
            |..::..||:..:||:...||.|:|.|...||
 Worm   314 LFSMILTINTCSHFIISMLMSSQYRKTAMNLF 345

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MsR1	NP_001261324.1	7tmA_FMRFamide_R-like	28..420	CDD:410630	97/410 (24%)
		TM helix 1	28..53	CDD:410630	10/24 (42%)
		TM helix 2	59..84	CDD:410630	5/24 (21%)
		TM helix 3	105..135	CDD:410630	8/37 (22%)
		TM helix 4	147..167	CDD:410630	4/19 (21%)
		TM helix 5	269..294	CDD:410630	8/24 (33%)
		TM helix 6	345..375	CDD:410630	10/29 (34%)
		TM helix 7	388..413	CDD:410630	5/24 (21%)
srw-134	NP_001309503.1	7TM_GPCR_Srw	40..347	CDD:402097	101/420 (24%)
		TM helix 1	40..62	CDD:410630	11/28 (39%)
		TM helix 2	69..94	CDD:410630	6/35 (17%)
		TM helix 3	112..144	CDD:410630	7/31 (23%)
		TM helix 4	158..178	CDD:410630	8/76 (11%)
		TM helix 5	218..243	CDD:410630	9/25 (36%)
		TM helix 6	268..295	CDD:410630	10/26 (38%)
		TM helix 7	309..334	CDD:410630	6/28 (21%)