Protein Alignment MsR1 and srw-2

DIOPT Version :10

• Sequence 1: NP_001261324.1
• Gene: MsR1 / 38298
• FlyBaseID: FBgn0035331
• Length: 556
• Species: Drosophila melanogaster
• Sequence 2: NP_503766.3
• Gene: srw-2 / 188012
• WormBaseID: WBGene00005749
• Length: 373
• Species: Caenorhabditis elegans
• Alignment Length: 407
• Identity: 78/407 - (19%)
• Similarity: 147/407 - (36%)
• Gaps: 124/407 - (30%)

  Fly    30 YVSLVVCILGTIANTLNIIVLTRREMRS-PTNAILTGLAVAD-LAVMLEYIPYTIHDYILTDSLP 92
            ||..::.......|.:::.||||:|:|: ....|:..:.:.| ::.:|.:|.::  .:.:.::|.
 Worm    42 YVIAILQFFAVAINLIHLSVLTRKELRAISIYRIMIVICILDIISEILSFISFS--PFWIRETLE 104

  Fly    93 REE---KLSYSWACFIKFHSIFAQVLHTISIWLTVTLAVWRYIAVGYPQKNRVWCGMRTTIITIT 154
            .:|   .::|..|...::......:....|.||.:.:|:.|.:|:.||..:
 Worm   105 GQECYVTVTYRDALIDQYGVPVLDMTQRGSSWLNLFMALLRVLAITYPMSS-------------- 155

  Fly   155 TAYVVCVLVVSPSLYLITAITEYVDQLDMNGKVINSI------PMTQYVIDYRNELLSARTAALN 213
               .:...|:.|...||:.|        .||  |.||      .:||..:|:..:
 Worm   156 ---AIEKPVIVPVFVLISLI--------FNG--ICSICVTWNFEVTQQYMDFSCD---------- 197

  Fly   214 ATPTSAPLNETVWLNASTLLTSTTTAAPPTPSPVVRNVTVYRLYHSDLALHNASLQNATFLIYSV 278
                                 .|....|...|..:|.|.|.:          ..|.:....||.
 Worm   198 ---------------------GTQNLLPANASRYIRTVPVGK----------KELHSTLVFIYG- 230

  Fly   279 VIKLIPCIALTILSVRLILALLEAKRRRKKLTSKPATPGASNGTKSPANGKAADRPRKNSKTLEK 343
            :||.:|.:...||:|.||:.|..|.:|||.:                               |:.
 Worm   231 IIKALPSLVEPILAVILIMELKRASQRRKTM-------------------------------LKS 264

  Fly   344 EKQTDRTTRMLLAVLLLFLITEFPQGI----MGLL--NAVLGDVFYLQCYLRLSDLMDILALINS 402
            :.:.:.||:::|.:.:...:.|.|.|.    .|..  :.::....||     :....:|..:.||
 Worm   265 DGKGENTTKLILFMTISSFLLEVPNGFSHFAFGFFTTSPLIKTASYL-----IMVFAEIFPVTNS 324

  Fly   403 SINFILYCSMSKQFRTT 419
            |.:..:...||..:|.|
 Worm   325 STHLFVCFFMSTLYRET 341

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MsR1	NP_001261324.1	7tmA_FMRFamide_R-like	28..420	CDD:410630	78/407 (19%)
		TM helix 1	28..53	CDD:410630	6/22 (27%)
		TM helix 2	59..84	CDD:410630	4/25 (16%)
		TM helix 3	105..135	CDD:410630	6/29 (21%)
		TM helix 4	147..167	CDD:410630	1/19 (5%)
		TM helix 5	269..294	CDD:410630	7/24 (29%)
		TM helix 6	345..375	CDD:410630	7/35 (20%)
		TM helix 7	388..413	CDD:410630	4/24 (17%)
srw-2	NP_503766.3	7TM_GPCR_Srw	39..348	CDD:402097	78/407 (19%)
		TM helix 1	42..64	CDD:410630	5/21 (24%)
		TM helix 2	73..95	CDD:410630	4/21 (19%)
		TM helix 3	121..143	CDD:410630	3/21 (14%)
		TM helix 4	162..176	CDD:410630	6/23 (26%)
		TM helix 5	212..245	CDD:410630	11/43 (26%)
		TM helix 6	272..294	CDD:410630	5/21 (24%)
		TM helix 7	309..335	CDD:410630	6/30 (20%)