Protein Alignment MsR1 and srw-136

DIOPT Version :10

• Sequence 1: NP_001261324.1
• Gene: MsR1 / 38298
• FlyBaseID: FBgn0035331
• Length: 556
• Species: Drosophila melanogaster
• Sequence 2: NP_503821.2
• Gene: srw-136 / 187331
• WormBaseID: WBGene00005883
• Length: 378
• Species: Caenorhabditis elegans
• Alignment Length: 409
• Identity: 82/409 - (20%)
• Similarity: 160/409 - (39%)
• Gaps: 119/409 - (29%)

  Fly    30 YVSLVVCILGTIANTLNIIVLTRREMRSPT-NAILTGLAVADLAVMLEYIPYTIHDYILTDSLPR 93
            |:| |:|||   .|.|:.::||::.|||.: |.|:..:|:.|:...|......|..:|...|
 Worm    42 YLS-VICIL---INILHFVILTKKSMRSSSINLIMAAVAIFDILTFLFQFKQIISHFIHASS--- 99

  Fly    94 EEKLSYSWACFIKFHSIFAQVLHTISIWLTVTLAVWRYIAVGYPQKNRVWCGMRTTIITITTAYV 158
                    .|..:|           |.|:|: :....::...:.::...|       :.::.|::
 Worm   100 --------PCLGRF-----------SYWITL-IDKSGFVIKDFSRRCSTW-------LFLSIAFI 137

  Fly   159 VCVLVVSPSLYLITAITEYVDQLDMNGKVINSIPMTQYVIDYRNELLSARTAALNATPTSAPLNE 223
            ..::|.:|              :::..|.:::.|...|.| :...|||..::|:.
 Worm   138 RTLIVRNP--------------MNLKYKQLSNQPTAFYTI-FGVFLLSLPSSAIQ---------- 177

  Fly   224 TVWLNASTLLTSTTTAAPPTPSPVVRNVTVYRLYHSDLALHNASLQNATFLIYSVVIKLIPCIAL 288
             ::.|....:...|...|........:|..|      ....||.|.....::.:::..:|||...
 Worm   178 -IFENNIIEIWQKTECQPQGELTYFIDVAEY------FMRENAVLVKVAIIMDALISNIIPCFLF 235

  Fly   289 TILSVRLILALLEAKRRRKKLTSKPATPGASNGTKSPANGKAADRPRKNSKTLEKEKQTDRTTRM 353
            .|::..|:..|.:.::.|||||                         |||.:...:.|  :||::
 Worm   236 PIVTFLLVKELFKTEKSRKKLT-------------------------KNSSSNHNDSQ--KTTKL 273

  Fly   354 LLAVLLLFLITEFPQGI--------MG-----LLNAVLGDVFYLQCYLRLSDLMDILALINSSIN 405
            :....::|.:.|||.|:        ||     ::.:..|::|            .:|...|:|.:
 Worm   274 VFYNTIIFFVAEFPLGVNTSITWFFMGAPGIMMIMSHFGNIF------------SLLLSANTSTH 326

  Fly   406 FILYCSMSKQFRTTFTLLF 424
            .:|...||.|:|.|..::|
 Worm   327 LVLCLLMSSQYRKTAKMVF 345

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MsR1	NP_001261324.1	7tmA_FMRFamide_R-like	28..420	CDD:410630	80/403 (20%)
		TM helix 1	28..53	CDD:410630	10/22 (45%)
		TM helix 2	59..84	CDD:410630	6/25 (24%)
		TM helix 3	105..135	CDD:410630	4/29 (14%)
		TM helix 4	147..167	CDD:410630	2/19 (11%)
		TM helix 5	269..294	CDD:410630	4/24 (17%)
		TM helix 6	345..375	CDD:410630	10/42 (24%)
		TM helix 7	388..413	CDD:410630	4/24 (17%)
srw-136	NP_503821.2	TM helix 1	36..61	CDD:410630	10/22 (45%)
		7TM_GPCR_Srw	38..348	CDD:402097	82/409 (20%)
		TM helix 2	68..93	CDD:410630	6/24 (25%)
		TM helix 3	113..143	CDD:410630	2/36 (6%)
		TM helix 4	157..177	CDD:410630	7/20 (35%)
		TM helix 5	216..241	CDD:410630	4/24 (17%)
		TM helix 6	266..295	CDD:410630	8/30 (27%)
		TM helix 7	309..334	CDD:410630	6/36 (17%)