Protein Alignment MsR1 and srw-115

DIOPT Version :10

• Sequence 1: NP_001261324.1
• Gene: MsR1 / 38298
• FlyBaseID: FBgn0035331
• Length: 556
• Species: Drosophila melanogaster
• Sequence 2: NP_503815.2
• Gene: srw-115 / 187325
• WormBaseID: WBGene00005862
• Length: 367
• Species: Caenorhabditis elegans
• Alignment Length: 408
• Identity: 84/408 - (20%)
• Similarity: 146/408 - (35%)
• Gaps: 129/408 - (31%)

  Fly    35 VCILGTIANTLNIIVLTRREMR-SPTNAILTGLAVADLAVMLEYIPYTI--HDYILTDSLPREEK 96
            |.|...:.|.::..:|||:.|| |..|.::..:|:.|:...|:.|...:  :.||..|..|
 Worm    45 VSIASILINLIHFFILTRKPMRTSSINILMAAIALFDILASLQQIELLLDRYSYIFFDCYP---- 105

  Fly    97 LSYSWACFIKFHSIFAQVL----HTISIWLTVTLAVWRYIAVGYPQ--KNRVWCGMRTTIITI-- 153
             :|::.  ::...:...|:    ...|.||.|.:|..|.:.|..|.  |....|..:.:.|.|
 Worm   106 -TYTYG--LELTKVLLDVVRDYSRRCSTWLIVFIAFIRTLIVRNPMSTKFEALCQPKASAIIIAG 167

  Fly   154 --TTAYVVCVLVVSPSLYLITAITEYVDQLDMNGKVINSIPMTQYVIDYRNELLSARTAALNATP 216
              .|::.|.||          ...||                 |::     |:....:.|.....
 Worm   168 ICATSFPVSVL----------KFLEY-----------------QFI-----EIEGLESCAKGPHH 200

  Fly   217 TSAPLNETVWLNASTLLTSTTTAAPPTPSPVVRNVTVYRLYHSDLALHNASLQNATFLIYSVVIK 281
            ..|         .|.|.|:                            ::..|....:|..|.|..
 Worm   201 IFA---------VSDLFTA----------------------------NDGFLAKYFYLFNSFVSD 228

  Fly   282 LIPCIALTILSVRLILALLEAKRRRKKLTSKPATPGASNGTKSPANGKAADRPRKNSKTLEKEKQ 346
            ::|||.|.|:::.|::.|..|.::|..|.|                               ..|.
 Worm   229 IVPCILLPIVTLLLVMDLWRAAKKRTNLIS-------------------------------VSKN 262

  Fly   347 TDRTTRMLLAVLLLFLITEFPQGI-MG---LLNAVLGDVFYLQCYL-RLSDLMDILALINSSINF 406
            .:..|.::..|.::|.|.|||.|: ||   :.|.|||    ||..: |.:.:..:|..:|:..:.
 Worm   263 HNSRTGLVFCVTIMFFIVEFPYGLSMGFVWMYNDVLG----LQHMMSRFAFMFAMLITLNTCTHL 323

  Fly   407 ILYCSMSKQFRTTFTLLF 424
            .:...:|..:|:|...:|
 Worm   324 FVCLIISSHYRSTAIYVF 341

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MsR1	NP_001261324.1	7tmA_FMRFamide_R-like	28..420	CDD:410630	82/402 (20%)
		TM helix 1	28..53	CDD:410630	5/17 (29%)
		TM helix 2	59..84	CDD:410630	5/26 (19%)
		TM helix 3	105..135	CDD:410630	7/33 (21%)
		TM helix 4	147..167	CDD:410630	6/23 (26%)
		TM helix 5	269..294	CDD:410630	8/24 (33%)
		TM helix 6	345..375	CDD:410630	11/33 (33%)
		TM helix 7	388..413	CDD:410630	3/25 (12%)
srw-115	NP_503815.2	TM helix 1	41..63	CDD:410630	5/17 (29%)
		7TM_GPCR_Srw	45..344	CDD:402097	84/408 (21%)
		TM helix 2	70..95	CDD:410630	5/24 (21%)
		TM helix 3	115..145	CDD:410630	7/29 (24%)
		TM helix 4	159..179	CDD:410630	6/29 (21%)
		TM helix 5	216..241	CDD:410630	8/24 (33%)
		TM helix 6	267..291	CDD:410630	10/23 (43%)
		TM helix 7	305..330	CDD:410630	3/24 (13%)