Protein Alignment MsR1 and srw-143

DIOPT Version :10

• Sequence 1: NP_001261324.1
• Gene: MsR1 / 38298
• FlyBaseID: FBgn0035331
• Length: 556
• Species: Drosophila melanogaster
• Sequence 2: NP_503798.3
• Gene: srw-143 / 186788
• WormBaseID: WBGene00005890
• Length: 368
• Species: Caenorhabditis elegans
• Alignment Length: 413
• Identity: 79/413 - (19%)
• Similarity: 144/413 - (34%)
• Gaps: 134/413 - (32%)

  Fly    26 NMHGYVSLVVCILGTIANTLNIIVLTRREMRSPT-NAILTGLAVADLAVML-----EYIPYTIHD 84
            |...|:|    |.....|..:.::|.|:.:||.: |.|:..:::.|:..||     .|.|..  :
 Worm    38 NYEHYLS----IASIFINIFHFLILIRKPLRSSSINIIMAFISIFDICSMLFRMKQSYGPSI--E 96

  Fly    85 YILTDSLPRE-------EKLSYSWACFIKFHSIFAQVLHTISIWLTVTLAVWRYIAVGYPQKNRV 142
            ||....:..:       ||:    ...:|.||      ...|.||..::|:.|.:.:..|...:.
 Worm    97 YIFDPCMQSKWYFNVYLEKI----LLVVKDHS------QRSSTWLLFSIALIRTLVIRNPMNPKY 151

  Fly   143 WCGMRTTIITITTAYVVCVLVVSPSLYLITAITEYVDQLDMNGKVINSIPMTQYVIDYRNELLSA 207
                              ..:..|...|.|.|            .||.|
 Worm   152 ------------------ERLAHPPTSLFTMI------------CINLI---------------- 170

  Fly   208 RTAALNATPTSAPLNETVWLNASTLLTSTTTAAPPTPSPVVRNVTVYRLYHSDLAL----HNASL 268
                      ..|::...:..:.  :||....:...|..|:       .|:.|::.    ::..:
 Worm   171 ----------FGPISIATFFGSD--ITSQNHTSSCDPDGVL-------FYYLDISASYKQNDGMI 216

  Fly   269 QNATFLIYSVVIKLIPCIALTILSVRLILALLEAKRRRKKLTSKPATPGASNGTKSPANGKAADR 333
            .....||.|||..:|||....|::|.|:..|.:|:..||:|.|.
 Worm   217 LKIYTLINSVVSTIIPCFIFPIVTVFLVKELWKAEANRKRLFSS--------------------- 260

  Fly   334 PRKNSKTLEKEKQTDRTTRMLLAVLLLFLITEFPQGI-MG---LLNAVLGDVFYLQCYLRLSDLM 394
                    :|...:.:.|:::|.:..:|.|.:||.|| :|   ..:...|.:..|.   .:|.:.
 Worm   261 --------KKVNDSSKNTQLVLFLTCVFFIAQFPIGISIGASYFFSETPGFMIILH---EISYIF 314

  Fly   395 DILALINSSINFILYCSMSKQFR 417
            .::.:.|:..:|.:...||.|:|
 Worm   315 SVILVANTFSHFFICIFMSSQYR 337

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MsR1	NP_001261324.1	7tmA_FMRFamide_R-like	28..420	CDD:410630	78/411 (19%)
		TM helix 1	28..53	CDD:410630	5/24 (21%)
		TM helix 2	59..84	CDD:410630	7/30 (23%)
		TM helix 3	105..135	CDD:410630	8/29 (28%)
		TM helix 4	147..167	CDD:410630	0/19 (0%)
		TM helix 5	269..294	CDD:410630	9/24 (38%)
		TM helix 6	345..375	CDD:410630	9/33 (27%)
		TM helix 7	388..413	CDD:410630	3/24 (13%)
srw-143	NP_503798.3	7TM_GPCR_Srw	38..347	CDD:402097	79/413 (19%)
		TM helix 2	68..96	CDD:410630	7/29 (24%)
		TM helix 3	114..144	CDD:410630	10/39 (26%)
		TM helix 4	158..178	CDD:410630	7/57 (12%)
		TM helix 5	217..242	CDD:410630	9/24 (38%)
		TM helix 6	264..294	CDD:410630	9/29 (31%)
		TM helix 7	307..333	CDD:410630	4/28 (14%)