Protein Alignment MsR1 and srw-8

DIOPT Version :10

• Sequence 1: NP_001261324.1
• Gene: MsR1 / 38298
• FlyBaseID: FBgn0035331
• Length: 556
• Species: Drosophila melanogaster
• Sequence 2: NP_503828.3
• Gene: srw-8 / 186615
• WormBaseID: WBGene00005755
• Length: 366
• Species: Caenorhabditis elegans
• Alignment Length: 439
• Identity: 86/439 - (19%)
• Similarity: 146/439 - (33%)
• Gaps: 158/439 - (35%)

  Fly    18 DNFHTSYKNMHGYVSLV------VCILGTIANTLNIIVLTRREMRSPTN---AILTGLAVADLAV 73
            |.|...|...|.|..:.      :|..|.:.|.:::::|||:|:|  ||   .::.|:.:.:|..
 Worm    26 DIFDYDYDIKHDYFDVARRVYTGLCTFGFLINLVHMVILTRKELR--TNLVYIVMIGICICELTQ 88

  Fly    74 MLEYIPYTIHDYILTDSLP-REEKLSYSWACFIKFHSIFAQVLHTISIWLT--------VTLAVW 129
            ...    ||..|.:|..:. |.|.:     |.:.:..:...||.|...:|:        :.|.|:
 Worm    89 SFT----TILSYFMTLGIVYRIENV-----CGLAYFHVMIDVLATTFQYLSRRCASILGLFLVVF 144

  Fly   130 RYIAVGYPQKNRVWCGMRTTIITITTAYVVCVLVVSPSLYLITAITEYVDQLDMNGKVINSIPMT 194
            |..::.:|..:.:...||..|        .|:||::.                       :|..:
 Worm   145 RTCSIIFPMSSAIDFVMRPKI--------GCLLVLTV-----------------------TIMSS 178

  Fly   195 QYVIDY--RNELLSARTAALNATPTSAPLNETVWLNASTLLTSTTTAAPPTPSPVVRNVTVYRLY 257
            .|...|  |.:::..|...|:...|                                    |.||
 Worm   179 AYSFLYFSRAKIVKERECYLHERST------------------------------------YVLY 207

  Fly   258 HSDLALHNASLQNATFLIYSVVIKLIPCIALTILSVRLILALLEAKRRRKKLTSKPATPGASNGT 322
                 .|..|.:...|.:....|.::.|....|::..||..|.:||:||
 Worm   208 -----THENSNKEMQFQLMDGYIAMVVCFLYIIVAGTLIFQLQKAKQRR---------------- 251

  Fly   323 KSPANGKAADRPRKNSKTLEKEKQTDRTTRMLLAVLLLFLITEFPQGIMGLLNAVLGDVFYLQCY 387
                            |.|:.||.|..:..:||.....|    |.:.|.|:.       ::|..|
 Worm   252 ----------------KNLKAEKSTSTSGLILLMATTAF----FSETIYGVF-------YFLDYY 289

  Fly   388 LRLSDLMD------------ILALINSSINFILYCSMSKQFRTTFTLLF 424
            :....:.|            ||.|::|..:......||.|:|.|...||
 Worm   290 VYYDKVFDNSMFQYLDSFVLILMLVSSFTHCFTCFLMSSQYRQTAKNLF 338

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MsR1	NP_001261324.1	7tmA_FMRFamide_R-like	28..420	CDD:410630	80/423 (19%)
		TM helix 1	28..53	CDD:410630	7/30 (23%)
		TM helix 2	59..84	CDD:410630	6/27 (22%)
		TM helix 3	105..135	CDD:410630	7/37 (19%)
		TM helix 4	147..167	CDD:410630	5/19 (26%)
		TM helix 5	269..294	CDD:410630	4/24 (17%)
		TM helix 6	345..375	CDD:410630	8/29 (28%)
		TM helix 7	388..413	CDD:410630	5/36 (14%)
srw-8	NP_503828.3	TM helix 1	45..66	CDD:410628	4/20 (20%)
		7TM_GPCR_Srw	49..341	CDD:402097	81/416 (19%)
		TM helix 2	75..100	CDD:410628	5/28 (18%)
		TM helix 3	121..143	CDD:410628	5/21 (24%)
		TM helix 4	168..184	CDD:410628	4/38 (11%)
		TM helix 5	219..238	CDD:410628	3/18 (17%)
		TM helix 6	265..285	CDD:410628	6/30 (20%)
		TM helix 7	302..327	CDD:410628	4/24 (17%)