Protein Alignment MsR1 and srw-51

DIOPT Version :10

• Sequence 1: NP_001261324.1
• Gene: MsR1 / 38298
• FlyBaseID: FBgn0035331
• Length: 556
• Species: Drosophila melanogaster
• Sequence 2: NP_507344.1
• Gene: srw-51 / 185526
• WormBaseID: WBGene00005798
• Length: 352
• Species: Caenorhabditis elegans
• Alignment Length: 431
• Identity: 92/431 - (21%)
• Similarity: 170/431 - (39%)
• Gaps: 140/431 - (32%)

  Fly    17 MDNFHTSYKNMHGYVSLVVCILGTIANTLNIIVLTRREMRSPT-NAILTGLAVADLAVMLEYIPY 80
            :|:|.....:...||..||.|:|.|.|..:.:||.|:.||..| |..:.|:|:.|.:.|:.::..
 Worm    10 IDDFLVQIYSYLNYVIFVVSIIGIILNVFHFLVLFRKSMRQLTINIFMIGIAICDFSQMISFVVV 74

  Fly    81 TIHDY--------ILTDSLPREEKLSYSWACFIKFHSIF---AQVLHTISIWLTVTLAVWRYIAV 134
            ....:        |..:..|.:..:.|      |.:.||   :.|...:::||.|:||:.|...:
 Worm    75 MTSQFYINYKTTQISPECYPPQSYIEY------KINHIFTFISNVSPKLAVWLGVSLAILRASVI 133

  Fly   135 GYPQ----KNRVWC--GMRTTIITITTAYVVCVLVVSPSLYLITAITEYVDQLDMNGKVINSIPM 193
            .:|.    :|.::.  |:| .::||...| .|
 Worm   134 RHPTNSSIQNYIYSKHGIR-ILLTICLPY-AC--------------------------------- 163

  Fly   194 TQYVIDYRNELLSARTAALNATPTSAPLNETVWLNASTLLTSTTTAAPP----TPSPVVRNVTVY 254
             .::.||              |..|..::|| |            ..||    |..|     ..|
 Worm   164 -YFIYDY--------------TAHSTTISET-W------------ELPPECANTSEP-----DTY 195

  Fly   255 RLYHSDLALHNASLQNATFLIYSVVIKLIPCIALTILSVRLILALLEAKRRRKKLTSKPATPGAS 319
            .||:::   ::.|....:..|..::.||||.|.|.:.:   |:.|.|.|:.||..|
 Worm   196 TLYYTE---YDESSFRISLFIDGILFKLIPSILLPLFT---IVLLYEMKKTRKVAT--------- 245

  Fly   320 NGTKSPANGKAADRPRKNSKTLEKEKQTDRTTRMLLAVLLLFLITEFPQGIMGLLNAVLGDVFYL 384
                              |::.:.....||:|:::..|.:.||::..|.||:.::.::     :|
 Worm   246 ------------------SRSFQNSNSKDRSTKLVTFVTITFLLSTVPLGILYIIKSI-----FL 287

  Fly   385 QCYL------RLSDLMDILALINSSINFILYCSMSKQFRTT 419
            |..:      :|..:..::::||.:::|::...||.|:|.|
 Worm   288 QSLVISNFANKLQSIFVLISIINGTLHFLICFFMSSQYRNT 328

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MsR1	NP_001261324.1	7tmA_FMRFamide_R-like	28..420	CDD:410630	90/420 (21%)
		TM helix 1	28..53	CDD:410630	10/24 (42%)
		TM helix 2	59..84	CDD:410630	6/25 (24%)
		TM helix 3	105..135	CDD:410630	10/32 (31%)
		TM helix 4	147..167	CDD:410630	5/19 (26%)
		TM helix 5	269..294	CDD:410630	7/24 (29%)
		TM helix 6	345..375	CDD:410630	9/29 (31%)
		TM helix 7	388..413	CDD:410630	4/30 (13%)
srw-51	NP_507344.1	7TM_GPCR_Srw	23..336	CDD:402097	90/418 (22%)
		TM helix 1	23..46	CDD:410630	10/22 (45%)
		TM helix 2	53..78	CDD:410630	5/24 (21%)
		TM helix 3	104..134	CDD:410630	9/29 (31%)
		TM helix 4	148..168	CDD:410630	6/55 (11%)
		TM helix 5	207..232	CDD:410630	7/27 (26%)
		TM helix 6	256..283	CDD:410630	9/26 (35%)
		TM helix 7	297..322	CDD:410630	4/24 (17%)