Protein Alignment MsR1 and srw-4

DIOPT Version :10

• Sequence 1: NP_001261324.1
• Gene: MsR1 / 38298
• FlyBaseID: FBgn0035331
• Length: 556
• Species: Drosophila melanogaster
• Sequence 2: NP_503785.3
• Gene: srw-4 / 185414
• WormBaseID: WBGene00005751
• Length: 367
• Species: Caenorhabditis elegans
• Alignment Length: 436
• Identity: 85/436 - (19%)
• Similarity: 157/436 - (36%)
• Gaps: 150/436 - (34%)

  Fly    20 FHTSYKNMHGYVSLVVCILGTIANTLNIIVLTRREMRSPTNAI---LTGLAVADL----AVMLEY 77
            |..:.|.:: :|..::...|...|.::..:|:|:.:|  ||::   :.|:...|:    ...|.:
 Worm    24 FDEAEKKLN-FVLAILQFFGFGINLVHFSILSRKHLR--TNSVYRLMIGICSCDIISHTLTFLAF 85

  Fly    78 IPYTIHDY-------ILTDSLPREEKLSYSWACFIKFHSIFAQVLHTISIWLTVTLAVWRYIAVG 135
            .|:.|.:.       .||        ::|..|..:.:..|...:....|.||.|.:|::|.::|.
 Worm    86 SPFWIREVRKKNQECFLT--------MTYRDAVLLLYPVIVLDITQRSSSWLAVLMALYRTLSVK 142

  Fly   136 YPQKNR----------VWCGMRTTIITITTAYVVCVLVVSPSLYLITAITEYVD----QLDMNGK 186
            ||...:          :|.             ::.||||:.:..|:......:|    ..|.:|
 Worm   143 YPMSTKMHKVSNPKWALWT-------------IIGVLVVNTAWTLVVFGRHKIDGRNIDYDCDG- 193

  Fly   187 VINSIPMTQYVIDYRNELLSARTAALNATPTSAPLNETVWLNASTLLTSTTTAAPPTPSPVVRNV 251
              |.:.::|...
 Worm   194 --NEVHLSQLRF----------------------------------------------------- 203

  Fly   252 TVYRLYHSDLALHNASLQNATFLIYSV--VIKLIPCIALTILSVRLILALLEAKRRRKKLTSKPA 314
                     :.|.:.||::...:|.|:  :||.:|.:...||:|.||:.|.:|.:|||.:
 Worm   204 ---------MVLVDTSLEHLHSIITSIYGIIKALPSLIDPILTVLLIIELRKASKRRKNI----- 254

  Fly   315 TPGASNGTKSPANGKAADRPRKNSKTLEKEKQTDRTTRMLLAVLLLFLITEFPQGIMGL-LNAVL 378
                         ||            |...::|.||:::|.|.:.|.|.|.|.|...: ..|..
 Worm   255 -------------GK------------EDCGKSDNTTKLVLFVTISFFILEVPNGFAHVTAGAFH 294

  Fly   379 GDVFYLQCYLRLSDLMDILALINSSINFILYCSMSKQFRTTFTLLF 424
            |:...|.....:....:||.:.|||.:..:..:||.|:|.|...:|
 Worm   295 GNPGILTISYMIQVFAEILPVFNSSSHIFICLAMSSQYRETSCEIF 340

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MsR1	NP_001261324.1	7tmA_FMRFamide_R-like	28..420	CDD:410630	81/422 (19%)
		TM helix 1	28..53	CDD:410630	4/24 (17%)
		TM helix 2	59..84	CDD:410630	7/31 (23%)
		TM helix 3	105..135	CDD:410630	7/29 (24%)
		TM helix 4	147..167	CDD:410630	4/19 (21%)
		TM helix 5	269..294	CDD:410630	7/26 (27%)
		TM helix 6	345..375	CDD:410630	10/30 (33%)
		TM helix 7	388..413	CDD:410630	5/24 (21%)
srw-4	NP_503785.3	TM helix 1	33..56	CDD:410630	4/22 (18%)
		7TM_GPCR_Srw	37..341	CDD:402097	82/422 (19%)
		TM helix 2	63..88	CDD:410630	3/24 (13%)
		TM helix 3	112..142	CDD:410630	7/29 (24%)
		TM helix 4	156..176	CDD:410630	6/32 (19%)
		TM helix 5	212..239	CDD:410630	7/26 (27%)
		TM helix 6	261..290	CDD:410630	10/28 (36%)
		TM helix 7	303..329	CDD:410630	5/25 (20%)