Protein Alignment MsR1 and srw-57

DIOPT Version :10

• Sequence 1: NP_001261324.1
• Gene: MsR1 / 38298
• FlyBaseID: FBgn0035331
• Length: 556
• Species: Drosophila melanogaster
• Sequence 2: NP_506997.2
• Gene: srw-57 / 185365
• WormBaseID: WBGene00005804
• Length: 356
• Species: Caenorhabditis elegans
• Alignment Length: 451
• Identity: 95/451 - (21%)
• Similarity: 168/451 - (37%)
• Gaps: 128/451 - (28%)

  Fly     1 MASGNNETEPLYCGSGMDNFHTSYKNM----------HGYVSLVVCILGTIANTLNIIVLTRREM 55
            |.:.:||.| .|..:..::| ..:.|:          ..::..:|.::|.:.|..::|||:|:.|
 Worm     1 MNASSNEME-YYDDTDYEDF-IFWNNIMQTIIPIFEHQSHLDFLVAVIGVLVNIFHLIVLSRKSM 63

  Fly    56 RSPT-NAILTGLAVADLAVMLEYIPYTIHDY---ILTDSLPREEKLSYSW-ACFIKFHSI-FAQV 114
            |..| |..|.|:|:.|...::..:...:.:|   ..|..:|.:.....|| :.|:..||| ..::
 Worm    64 RLYTINLFLIGIAICDFLRLIFNVLVALSNYYHKYQTSIMPEDCTPPKSWLSFFVSVHSITIPRI 128

  Fly   115 LHTISIWLTVTLAVWRYIAVGYPQKNRVWCGMRTTIITITTAYVVCVLVVSPSLYLITAITEYVD 179
            ...:::...|.:||.|.|.:.|| .||....::.:...|....:||:..: |..:.....||
 Worm   129 FQKLAVCFGVAMAVLRVIILKYP-LNRRGQNLKRSSSGICILLIVCIPHI-PFWFFDLQWTE--- 188

  Fly   180 QLDMNGKVINSIPMTQYVIDYRNELLSARTAALNATPTSAPLNETVWLNASTLLTSTTTAAPPTP 244
             :..||                                       :|                .|
 Worm   189 -IQENG---------------------------------------IW----------------KP 197

  Fly   245 SPVVRNVTVYRLYHSDLALHNASLQNATFL-IYSVVIKLIPCIALTILSVRLILALLEAKRRRKK 308
            .|...|...:.| |.:.::......:.|.| |..|:..:||.:.|.|::..||...    :..||
 Worm   198 PPGCENFNDHNL-HIEYSVKPGEYSSETLLRIEGVLFTVIPSLILPIVTGTLIYFF----KTLKK 257

  Fly   309 LTSKPATPGASNGTKSPANGKAADRPRKNSKTLEKEKQTDRTTRMLLAVLLLFLITEFPQGIMGL 373
            .||.                      |.|.       ...|:|.|:..|.:.|:|..||     |
 Worm   258 STSS----------------------RNND-------HNARSTIMVTLVAVTFVIATFP-----L 288

  Fly   374 LNAVLGDVFYLQCYLRLSDLM-------DILALINSSINFILYCSMSKQFRTTFTLLFRPK 427
            |...|.|  :|....||:..:       :.::|||.:::|:|...:|.|::.|...:|..|
 Worm   289 LLTYLVD--FLSLGYRLAFFIILFGAFCEFVSLINGTLHFLLCAFISTQYQKTVREMFGRK 347

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MsR1	NP_001261324.1	7tmA_FMRFamide_R-like	28..420	CDD:410630	85/405 (21%)
		TM helix 1	28..53	CDD:410630	6/24 (25%)
		TM helix 2	59..84	CDD:410630	6/25 (24%)
		TM helix 3	105..135	CDD:410630	8/30 (27%)
		TM helix 4	147..167	CDD:410630	3/19 (16%)
		TM helix 5	269..294	CDD:410630	8/25 (32%)
		TM helix 6	345..375	CDD:410630	9/29 (31%)
		TM helix 7	388..413	CDD:410630	7/31 (23%)
srw-57	NP_506997.2	7TM_GPCR_Srw	38..347	CDD:402097	87/410 (21%)
		TM helix 2	68..93	CDD:410630	5/24 (21%)
		TM helix 3	119..149	CDD:410630	8/29 (28%)
		TM helix 4	160..179	CDD:410630	3/19 (16%)
		TM helix 5	222..247	CDD:410630	8/24 (33%)
		TM helix 6	265..295	CDD:410630	11/41 (27%)
		TM helix 7	308..333	CDD:410630	5/24 (21%)