Protein Alignment MsR1 and frpr-4

DIOPT Version :10

• Sequence 1: NP_001261324.1
• Gene: MsR1 / 38298
• FlyBaseID: FBgn0035331
• Length: 556
• Species: Drosophila melanogaster
• Sequence 2: NP_001309544.1
• Gene: frpr-4 / 183763
• WormBaseID: WBGene00016909
• Length: 362
• Species: Caenorhabditis elegans
• Alignment Length: 417
• Identity: 82/417 - (19%)
• Similarity: 161/417 - (38%)
• Gaps: 120/417 - (28%)

  Fly    17 MD--NFHTSYKNMHGYVSLVVCILGTIANTLNIIVLTRREMRSPTNAILTGLAVADLAVMLEYIP 79
            ||  :||    .:..:|.|...::|.:.|.|::...:|:..:|....:|..|:|:|:.:::..:|
 Worm     2 MDSMDFH----RIMAFVYLPTILIGLLGNLLSLYAYSRKNRKSMVGFLLYSLSVSDIFLLVFALP 62

  Fly    80 YTIHDY--ILTDSLPREEKLSYSWACFIKFHSIFAQVLHTISIWLTVTLAVWRYIAVGYPQKNRV 142
            .....|  |.||     |:.|:..|...|:......:..|.|:::.|.:.:.|:|||..|.:.::
 Worm    63 LFSIMYLPIWTD-----EQRSFVVAYTAKYVYPLCMMAKTCSLYIMVLITIERWIAVCRPLEVQI 122

  Fly   143 WCGMRTTIITITTAYVVCVLVVSPSLYLITAITEYVDQLDMNGKVINSIPMTQYVIDYRNELLSA 207
            ||...|                  |.|.|.||..:       ..|:|.....::.|:|.:.|...
 Worm   123 WCRYTT------------------SSYSIAAIITF-------AVVLNFARFFEFEIEYIDGLAFF 162

  Fly   208 RTAALNATPTSAPLNETVWLNASTLLTSTTTAAPPTPSPVVRNVTVYRLYHSDLALHNASLQNAT 272
            |...|:        :|..|.                          |.:::
 Worm   163 RRDLLD--------SEKHWW--------------------------YFMFY-------------- 179

  Fly   273 FLIYSVVIK-LIPCIALTILSVRLILALLEAKRRRKKLTSKPATPGASNGTKSPANGKAADRPRK 336
            |:|.|::.. |:|.:.:.:.::.:|..|...|:.|..:
 Worm   180 FIIISIIFDYLVPFVIMFVANMLIISELRRTKKERSLM--------------------------- 217

  Fly   337 NSKTLEKEKQTDRTTRMLLAVLLLFLITEFPQGIMGLLNAVLGDVFYLQ-CYLR-LSDLMDILAL 399
               |::::|: ..||.|||.:.:.|....|....:.|..:.:|....:| .||. |.::.:.|.:
 Worm   218 ---TIQQQKE-QNTTVMLLVITIFFGFCHFFSMALKLAESFVGKFLTIQNIYLEMLGEIFNYLII 278

  Fly   400 INSSINFILYCSMSKQFRTTFTLLFRP 426
            |:::..|.:|...|::||.....:::|
 Worm   279 IHTASTFFIYYMFSEKFRQIIKGIWKP 305

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MsR1	NP_001261324.1	7tmA_FMRFamide_R-like	28..420	CDD:410630	77/396 (19%)
		TM helix 1	28..53	CDD:410630	5/24 (21%)
		TM helix 2	59..84	CDD:410630	5/24 (21%)
		TM helix 3	105..135	CDD:410630	7/29 (24%)
		TM helix 4	147..167	CDD:410630	1/19 (5%)
		TM helix 5	269..294	CDD:410630	5/25 (20%)
		TM helix 6	345..375	CDD:410630	9/29 (31%)
		TM helix 7	388..413	CDD:410630	6/25 (24%)
frpr-4	NP_001309544.1	7tmA_FMRFamide_R-like	33..299	CDD:410630	72/374 (19%)
		TM helix 2	42..67	CDD:410630	5/24 (21%)
		TM helix 3	85..115	CDD:410630	7/29 (24%)
		TM helix 4	127..147	CDD:410630	8/44 (18%)
		TM helix 5	177..202	CDD:410630	5/38 (13%)
		TM helix 6	222..252	CDD:410630	9/30 (30%)
		TM helix 7	265..292	CDD:410630	7/26 (27%)