Protein Alignment MsR1 and srw-117

DIOPT Version :10

• Sequence 1: NP_001261324.1
• Gene: MsR1 / 38298
• FlyBaseID: FBgn0035331
• Length: 556
• Species: Drosophila melanogaster
• Sequence 2: NP_503812.1
• Gene: srw-117 / 183444
• WormBaseID: WBGene00005864
• Length: 372
• Species: Caenorhabditis elegans
• Alignment Length: 451
• Identity: 80/451 - (17%)
• Similarity: 154/451 - (34%)
• Gaps: 157/451 - (34%)

  Fly     2 ASGNNETEPLYCGSGMDNFHTSYKNMHGYVSLVVCILGTIANTLNIIVLTRREMR-SPTNAILTG 65
            |...|.|....|....:....|| :...| |..:.:...:.|.:::.:|||:.|| |..|.::..
 Worm    14 AGFQNSTAKSLCNFEKNFIPFSY-SFQSY-SSEISVSSILINIVHVFILTRKPMRTSSINILMAA 76

  Fly    66 LAVADLAVMLEYIPYTIHDYILTDSLPREEKLSYSWACFIKFHSIFAQVLHTISIWLTVTLAVWR 130
            :|:.|:....:.|.                      ..|.:..|||.:...|.:..:.:|.|::.
 Worm    77 VALFDIFTNFQQIE----------------------IIFERNTSIFFECFPTDTYGVILTRAIFD 119

  Fly   131 YIAVGYPQKNRVWCGMRTTIITITTAYVVCVLVVSPSLYLITAITEYVDQLDMNGKVINSIPMTQ 195
             |...|.::...|       ..::.|::..::|
 Worm   120 -IVNDYSRRCSTW-------FIVSIAFMRTLMV-------------------------------- 144

  Fly   196 YVIDYRNELLSARTAALNATPTSAPLNETVWLNASTLLTSTTTAAPPTPSPVVRNVTVYRLYHSD 260
                 ||.|.|...:..|.             |||.::.|...|| ..|      :::::.:.:.
 Worm   145 -----RNPLHSTYQSLGNP-------------NASVIVISGVCAA-SLP------ISIFKFFETQ 184

  Fly   261 L-----ALHNASLQNATF--------------------LIYSVVIKLIPCIALTILSVRLILALL 300
            .     :|:..:||...:                    |..|.|..:|||:.|.|::|.|::.|.
 Worm   185 FFVVTESLYVCALQGTYYLAAMSHFFMKNNGFIAKYFSLFNSFVSDIIPCLLLPIVTVLLVMDLW 249

  Fly   301 EAKRRRKKLTSKPATPGASNGTKSPANGKAADRPRKNSKTLEKEKQTDRTTRMLLAVLLLFLITE 365
            :..::|..:.|      .||              :.|.::         .|.::..|.::|.:.|
 Worm   250 KTAKKRANIVS------VSN--------------KNNFRS---------KTGLVFCVTIMFFLVE 285

  Fly   366 FPQGIMGLLNAVLGDVFYL-------QCYLRLSDLMDILALINSSINFILYCSMSKQFRTT 419
            ||.|      :.||.|:..       |....:..:..:|..:|:..:|.:...:|.|:|.|
 Worm   286 FPYG------SSLGAVWMYKNAPGMQQILAHVGFIFSMLITLNTCTHFFICLLISSQYRKT 340

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MsR1	NP_001261324.1	7tmA_FMRFamide_R-like	28..420	CDD:410630	74/425 (17%)
		TM helix 1	28..53	CDD:410630	5/24 (21%)
		TM helix 2	59..84	CDD:410630	4/24 (17%)
		TM helix 3	105..135	CDD:410630	7/29 (24%)
		TM helix 4	147..167	CDD:410630	2/19 (11%)
		TM helix 5	269..294	CDD:410630	9/44 (20%)
		TM helix 6	345..375	CDD:410630	7/29 (24%)
		TM helix 7	388..413	CDD:410630	3/24 (13%)
srw-117	NP_503812.1	7TM_GPCR_Srw	53..348	CDD:402097	72/410 (18%)
		TM helix 2	70..95	CDD:410630	5/46 (11%)
		TM helix 3	113..145	CDD:410630	7/76 (9%)
		TM helix 4	159..179	CDD:410630	7/26 (27%)
		TM helix 5	218..243	CDD:410630	8/24 (33%)
		TM helix 6	270..296	CDD:410630	9/31 (29%)
		TM helix 7	309..334	CDD:410630	3/24 (13%)