Protein Alignment MsR1 and srw-124

DIOPT Version :10

• Sequence 1: NP_001261324.1
• Gene: MsR1 / 38298
• FlyBaseID: FBgn0035331
• Length: 556
• Species: Drosophila melanogaster
• Sequence 2: NP_503810.2
• Gene: srw-124 / 183440
• WormBaseID: WBGene00005871
• Length: 368
• Species: Caenorhabditis elegans
• Alignment Length: 449
• Identity: 85/449 - (18%)
• Similarity: 157/449 - (34%)
• Gaps: 141/449 - (31%)

  Fly     1 MASGNNETEPLYCG------SGMDNFHTSYKNMHGYVS---LVVCILGTIANTLNIIVLTRREMR 56
            |.|...:.|..|.|      ..:..|..|:.....|::   ..|.||..:.|.|::.:|||:.||
 Worm     2 MYSDCRDLERFYSGFRKSTAKSLCEFEKSFVTFSFYITGYVYEVSILSILINILHLFILTRKSMR 66

  Fly    57 -SPTNAILTGLAVADLAVMLEYIPYTI--HDYILTDSLPREEKLSYSWACFIKFHSIFAQVLHTI 118
             |..|.::..:|:.|:...|.:|...:  :.|::....|.:   :|..........:........
 Worm    67 TSSINILMAAVALFDIFASLVHIQLFLEQYSYLIFKCFPTD---TYGLVLTRTLLIVVKDFSRRC 128

  Fly   119 SIWLTVTLAVWRYIAVGYP-QKNRVWCGM-RTTIITITTAYVVCVLVVSPSLYLITAITEYVDQL 181
            |.||.|.:|:.|.:.:..| ....:..|. :.::|.|..   :|...:..|::....|
 Worm   129 STWLIVFIALIRTLIIRNPLSPKHILLGKPKASLIVIAG---ICAANLPISIFKFFEI------- 183

  Fly   182 DMNGKVINSIPMTQYVIDYRNELLSARTAALNATPTSAPLNETVWLNASTLLTSTTTAAPPTPSP 246
                         |:|.                                 :..|....||
 Worm   184 -------------QFVF---------------------------------VTISKHHCAP----- 197

  Fly   247 VVRNVTVYRLYHSDLALH-NASLQNATFLIYSVVIKLIPCIALTILSVRLILALLEAKRR-RKKL 309
               ..:.|.:..|:|.|. |..|........|.:..:||||.|.|::..|::.||:.::: |.::
 Worm   198 ---EGSYYFIASSELFLRDNGFLAKYFNFFNSFMSDMIPCILLPIVTCLLVMDLLKTRKKCRARI 259

  Fly   310 TSKPATPGASNGTKSPANGKAADRPRKNSKTLEKEKQTDRTTRMLLAVLLLFLITEFP------- 367
            ::|      :|.::    ||                     |.::..|.::|.|.|||
 Worm   260 SAK------NNNSR----GK---------------------TGLVFCVAIMFFIVEFPFGLSVGS 293

  Fly   368 -------QGIMGLLNAVLGDVFYLQCYLRLSDLMDILALINSSINFILYCSMSKQFRTT 419
                   .|:..:|| ..|.:|            .:|..:|:..:.|:...:|.|:|:|
 Worm   294 AWLFMSSPGVQNILN-FFGYMF------------TVLISVNACTHLIVCLIVSSQYRST 339

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MsR1	NP_001261324.1	7tmA_FMRFamide_R-like	28..420	CDD:410630	78/416 (19%)
		TM helix 1	28..53	CDD:410630	8/27 (30%)
		TM helix 2	59..84	CDD:410630	5/26 (19%)
		TM helix 3	105..135	CDD:410630	6/29 (21%)
		TM helix 4	147..167	CDD:410630	3/19 (16%)
		TM helix 5	269..294	CDD:410630	7/24 (29%)
		TM helix 6	345..375	CDD:410630	8/43 (19%)
		TM helix 7	388..413	CDD:410630	3/24 (13%)
srw-124	NP_503810.2	7TM_GPCR_Srw	41..347	CDD:402097	77/410 (19%)
		TM helix 2	70..97	CDD:410630	5/26 (19%)
		TM helix 3	115..145	CDD:410630	6/29 (21%)
		TM helix 4	159..179	CDD:410630	4/22 (18%)
		TM helix 5	218..243	CDD:410630	7/24 (29%)
		TM helix 6	264..295	CDD:410630	10/55 (18%)
		TM helix 7	308..333	CDD:410630	6/37 (16%)