Protein Alignment MsR1 and srw-127

DIOPT Version :10

• Sequence 1: NP_001261324.1
• Gene: MsR1 / 38298
• FlyBaseID: FBgn0035331
• Length: 556
• Species: Drosophila melanogaster
• Sequence 2: NP_504776.2
• Gene: srw-127 / 183173
• WormBaseID: WBGene00005874
• Length: 380
• Species: Caenorhabditis elegans
• Alignment Length: 419
• Identity: 89/419 - (21%)
• Similarity: 163/419 - (38%)
• Gaps: 142/419 - (33%)

  Fly    30 YVSLVVCILGTIANTLNIIVLTRREMRSPT-NAILTGLAVADLAVMLEYIPYTIHDYILTDSLPR 93
            |:|||..|:    |.|:|:||||:.:||.: |.|:..:|:.|:...|..:...|.|.:
 Worm    45 YISLVSIII----NILHIVVLTRKPLRSSSINVIMAAVAIFDVGAQLRPVQIAIVDIV------- 98

  Fly    94 EEKLSYSWACFIK---FHSIFAQV-LHTI-------SIWLTVTLAVWRYIAVGYPQKNRVWCGMR 147
                :..:.|.::   ::.:.::: |.||       |.||...:|:.|.:.|..|..:..   .|
 Worm    99 ----NLFYPCVLQLDSYNQLISEIALETIKDYSRRCSTWLCFLVALIRTLVVRNPMNSNY---ER 156

  Fly   148 TTIITITTAYVVCVLVVSPSLYLITAITEY----VDQLDMNGKVINSIPMTQYVIDYRNELLSAR 208
            .|..:....:::.|:|.| .|:.|..:..|    .::.|:....:.:     |..||....|.
 Worm   157 LTYSSTAIVFILIVVVFS-GLFNIYQLFSYKIAEEEKFDVCFDYVKA-----YFRDYTQLFLK-- 213

  Fly   209 TAALNATPTSAPLNETVWLNASTLLTSTTTAAPPTPSPVVRNVTVYRLYHSDLALHNASLQNATF 273
                               |.|.||                     :|::...||       |:|
 Worm   214 -------------------NNSRLL---------------------KLWNFVNAL-------ASF 231

  Fly   274 LIYSVVIKLIPCIALTILSVRLILALLEAKRRRKKLTSKPATPGASNGTKSPANGKAADRPRKNS 338
                    :||.:|..::::.||..||:|.:.|:|:||
 Worm   232 --------IIPSVAFPLVTIFLIRELLKADKMRRKMTS--------------------------- 261

  Fly   339 KTLEKEKQTDRTTRMLLAVLLLFLITEFPQGI-MGLLNAVLGDVFYLQCYLR-LSDLMDILALI- 400
             |..|.|::..||::::...::|.|..||.|: ||..        ||...:: ::.:.:.|..:
 Worm   262 -TSSKLKESRNTTKVVVYNTIIFSIVLFPIGVTMGFQ--------YLFIEIKGITRIFEYLGFVF 317

  Fly   401 ------NSSINFILYCSMSKQFRTTFTLL 423
                  |:..:||:...:|.|:..|..||
 Worm   318 SMFFSANTMSHFIICLLISSQYNDTAKLL 346

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MsR1	NP_001261324.1	7tmA_FMRFamide_R-like	28..420	CDD:410630	86/414 (21%)
		TM helix 1	28..53	CDD:410630	11/22 (50%)
		TM helix 2	59..84	CDD:410630	6/25 (24%)
		TM helix 3	105..135	CDD:410630	8/40 (20%)
		TM helix 4	147..167	CDD:410630	5/19 (26%)
		TM helix 5	269..294	CDD:410630	5/24 (21%)
		TM helix 6	345..375	CDD:410630	10/30 (33%)
		TM helix 7	388..413	CDD:410630	4/32 (13%)
srw-127	NP_504776.2	7TM_GPCR_Srw	42..350	CDD:402097	89/419 (21%)
		TM helix 2	71..96	CDD:410630	6/24 (25%)
		TM helix 3	117..147	CDD:410630	8/29 (28%)
		TM helix 4	161..181	CDD:410630	5/20 (25%)
		TM helix 5	219..244	CDD:410630	9/60 (15%)
		TM helix 6	267..297	CDD:410630	10/29 (34%)
		TM helix 7	311..336	CDD:410630	4/24 (17%)