Protein Alignment MsR1 and frpr-1

DIOPT Version :10

• Sequence 1: NP_001261324.1
• Gene: MsR1 / 38298
• FlyBaseID: FBgn0035331
• Length: 556
• Species: Drosophila melanogaster
• Sequence 2: NP_509368.3
• Gene: frpr-1 / 182105
• WormBaseID: WBGene00015323
• Length: 378
• Species: Caenorhabditis elegans
• Alignment Length: 458
• Identity: 94/458 - (20%)
• Similarity: 171/458 - (37%)
• Gaps: 155/458 - (33%)

  Fly    33 LVVCILGTIANTLNIIVLTRREMRSPTNAILTGLAVADLAVMLEYIPYTIHDYILTDSLPREEKL 97
            |:.| ||.|.|.|:....:||||.|..|..|..||.:|:.::|.    ....:.|.:...|.|
 Worm    56 LIGC-LGLIGNALSAFTYSRREMISSLNVYLFALACSDIVIILT----AFFLFFLENMRKRSE-- 113

  Fly    98 SYSWACFIKFHSIFAQVL-------HTISIWLTVTLAVWRYIAVGYPQK-NRVWCGMRTTIITIT 154
               ||.:  :.::.:.|:       .|:|:::||..|....:.|...:| ...:|.:.|:|:...
 Worm   114 ---WATY--YFAVLSPVMFPLGLTAQTMSVFITVASAFDCLVLVAASEKFKSKFCSVNTSILVGN 173

  Fly   155 ----TAYVVCVLVVSPSLYLITAITEYVDQLDMNGKVINSIPMTQ-YVIDYRNELLSARTAALNA 214
                ...:||:.:: ..::|:             |...||..|.: ||||..:.:.:  ||:.:.
 Worm   174 FNDFKNVIVCLKII-VKIFLL-------------GIFYNSPHMYEIYVIDCWSTMYN--TASKDV 222

  Fly   215 TPTSAPLNETVWLNASTLLTSTTTAAPPTPSPVVRNVTVYRLYHSDLALHNASLQNATFLIYSVV 279
            .||:...|                         |..|.:|.:|                 :|::|
 Worm   223 CPTALRSN-------------------------VDYVRIYYVY-----------------MYTIV 245

  Fly   280 IKLIPCIALTILSVRLILALLEAKRRRKKLTSKPATPGASNGTKSPANGKAADRPRKNSKTLEKE 344
            :.:.|.:.|.:::..:::::     ||               :.||           ||
 Worm   246 MAVGPVLLLIVINTAIVISM-----RR---------------SSSP-----------NS------ 273

  Fly   345 KQTDRTTRMLLAVL-----LLFLITEFPQGIMGLLNAVLGDVFYLQCYLRLSDLMDILALINSSI 404
             ::|..|.:|:..|     :|.|...|.:.:.|::|:.            |.||.:::.::|||.
 Worm   274 -ESDIITLVLVVCLFISCNVLPLTVNFLELLFGIINSY------------LIDLSNLMVVVNSSC 325

  Fly   405 NFILYCSMSKQFRTTFTLLFRPKFLDKWLPVAQDEMAAARAERSAVAPVLEKGRQQPQVVMASTT 469
            ||::|.:....||.|.....|                 |...|.|.|......|..|:|.:....
 Worm   326 NFLIYYTFGSNFRRTLRYYVR-----------------AALNRRAPAQNAANNRTPPRVKLCLPP 373

  Fly   470 TNI 472
            |.:
 Worm   374 TEV 376

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MsR1	NP_001261324.1	7tmA_FMRFamide_R-like	28..420	CDD:410630	84/404 (21%)
		TM helix 1	28..53	CDD:410630	7/19 (37%)
		TM helix 2	59..84	CDD:410630	6/24 (25%)
		TM helix 3	105..135	CDD:410630	6/36 (17%)
		TM helix 4	147..167	CDD:410630	4/23 (17%)
		TM helix 5	269..294	CDD:410630	4/24 (17%)
		TM helix 6	345..375	CDD:410630	8/34 (24%)
		TM helix 7	388..413	CDD:410630	9/24 (38%)
frpr-1	NP_509368.3	7tmA_FMRFamide_R-like	48..341	CDD:410630	84/404 (21%)
		TM helix 1	49..75	CDD:410630	7/19 (37%)
		TM helix 2	81..106	CDD:410630	6/28 (21%)
		TM helix 3	123..153	CDD:410630	6/29 (21%)
		TM helix 4	166..201	CDD:410630	8/48 (17%)
		TM helix 5	235..260	CDD:410630	6/41 (15%)
		TM helix 6	271..301	CDD:410630	10/47 (21%)
		TM helix 7	309..334	CDD:410630	9/36 (25%)